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Topic Review
UBA1 Gene
Ubiquitin like modifier activating enzyme 1.
  • 379
  • 23 Dec 2020
Topic Review
UAV-Based Applications for Plant Disease Detection and Monitoring
Remote sensing technology is vital for precision agriculture, aiding in early issue detection, resource management, and environmentally friendly practices. Recent advances in remote sensing technology and data processing have propelled unmanned aerial vehicles (UAVs) into valuable tools for obtaining detailed data on plant diseases with high spatial, temporal, and spectral resolution. Given the growing body of scholarly research centered on UAV-based disease detection, a comprehensive review and analysis becomes imperative to provide a panoramic view of evolving methodologies in plant disease monitoring and to strategically evaluate the potential and limitations of such strategies.
  • 375
  • 27 Oct 2023
Topic Review
UASs Application in Viticultural Scenarios
New technologies for management, monitoring, and control of spatio-temporal crop variability in precision viticulture scenarios are numerous. Remote sensing relies on sensors able to provide useful data for the improvement of management efficiency and the optimization of inputs. unmanned aerial systems (UASs) are the newest and most versatile tools, characterized by high precision and accuracy, flexibility, and low operating costs. 
  • 522
  • 15 Mar 2021
Topic Review
Tyrp1 Mutant Variants and OCA3
Oculocutaneous albinism type 3 (OCA3) is an autosomal recessive disorder caused by mutations in the TYRP1 gene. Tyrosinase-related protein 1 (Tyrp1) is involved in eumelanin synthesis, catalyzing the oxidation of 5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA) to 5,6-indolequinone-2-carboxylic acid (IQCA).
  • 530
  • 29 Oct 2021
Topic Review
Tyrosyl-DNA Phosphodiesterase 1
Tyrosyl-DNA phosphodiesterase 1 (TDP1) is an important repair enzyme that removes various covalent adducts from the 3′ end of DNA. Particularly, covalent complexes of topoisomerase 1 (TOP1) with DNA stabilized by DNA damage or by various chemical agents are an examples of such adducts. 
  • 432
  • 27 Mar 2023
Topic Review
Tyrosinemia
Tyrosinemia is a genetic disorder characterized by disruptions in the multistep process that breaks down the amino acid tyrosine, a building block of most proteins. If untreated, tyrosine and its byproducts build up in tissues and organs, which can lead to serious health problems.    
  • 428
  • 23 Dec 2020
Topic Review
Tyrosine Kinase Syk
Platelet-rich thrombi formed in vivo in mice have been shown to be composed of a core and shell region. Different pathways regulate the formation and stability of these two regions and understanding them may result in new ways to treat arterial thrombosis. The distinguishing feature between these two regions is the absence of fibrin in the shell, which indicates that in-vitro flow-based assays over thrombogenic surfaces, in the absence of coagulation, can be used to resemble this region.  Glycoprotein VI (GPVI) is a platelet immunoglobulin receptor which is known as a receptor for collagen and has been shown to contribute to the stability of platelet aggregates on collagen at high shear. In recent years GPVI has also been shown to be a receptor for fibrin and fibrinogen. Since the activation of GPVI by fibrinogen is also dependent on integrin αIIbβ3, with the interplay of the two receptors driving platelet adhesion and activation, blocking signalling pathways common to both receptors may have a greater antithrombotic effect than blocking GPVI alone. Therefore in this study, we have investigated the contribution of Syk tyrosine kinase, which plays a critical role in signalling by integrin αIIbβ3 and GPVI, in the stability of platelet aggregates formed on collagen or atherosclerotic plaque homogenate at arterial shear (1000 s-1). The results show that Syk regulates thrombus stability in the absence of fibrin. The fact that inhibitors of Syk are currently used for the treatment of patients with refractory immune thrombocytopenia (ITP) without increasing the risk of bleeding, indicate that Syk inhibitors may represent a new class of antiplatelet agent with reduced bleeding risk compared to current drugs.
  • 485
  • 17 Jan 2022
Topic Review
Tyrosine Hydroxylase Phosphorylation
Tyrosine hydroxylase (TH) is the rate-limiting enzyme of dopamine biosynthesis. The phosphorylation of TH is strictly regulated.
  • 835
  • 06 Nov 2020
Topic Review
Tyrosine Hydroxylase Deficiency
Tyrosine hydroxylase (TH) deficiency is a disorder that primarily affects movement, with symptoms that may range from mild to severe.  
  • 506
  • 23 Dec 2020
Topic Review
TYROBP Gene
TYRO protein tyrosine kinase binding protein.
  • 388
  • 23 Dec 2020
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