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Topic Review
Biography
Topic Review
Carrageenan
Carrageenan (CGN) is a sulfated galactose copolymer composed of alternating units of D-galactose and 3,6-anhydro-galactose joined by α-1,3 and β-1,4-glycosidic linkages.
889
23 Sep 2020
Topic Review
Fish as Nutraceuticals
Fish is considered as an affordable source of protein, serving a worldwide population as well as a source of nutraceutical. Bioactive components present in our diet play a major therapeutic role against human diseases.
888
21 Jan 2022
Topic Review
Tubulin Post-Translational Modifications
Microtubules (MTs) are dynamic structures that are part of the cell cytoskeleton. They play important roles in various cellular functions, such as intracellular organization and transport, cell division, and cell migration. MTs are made up of α/β-tubulin heterodimers that display diversity due to the existence of different tubilin isotypes and post-translational modifications (PTMs). One specific PTM, tubulin-acetylation, occurs inside the MT lumen and has been pointed out as a hallmark of stable old MTs. However, the question if it is a cause or a consequence of long-lived MTs has never been clarified. The view on tubulin acetylation is that this modification alters the mechanical properties of MTs allowing MTs to bend and to resist age-related lattice damage caused by multiple interactions with different factors during their existence. However, how this ability of MTs to survive structural damage is translated into specific cellular functions is still controversial, and it is far from being elucidated. This PTM is also associated with cellular responses to stress and various human pathologies.The regulation of enzymes involved in tubulin acetylation and deacetylation is important for maintaining proper cell physiology.
887
17 Apr 2023
Topic Review
Floral Scents in Roses
Floral scents possess high ornamental and economic values to rose production in the floricultural industry. The floral scent is one of the most important traits in plants, which is essential to the fertilization of angiosperm plants by attracting and guiding pollinators. Molecular bases of floral scent production have been studied in the rose as well as their genetic inheritance. Some significant achievements have been acquired, such as the comprehensive rose genome and the finding of a novel geraniol synthase in plants.
887
05 Aug 2022
Topic Review
Avian Influenza Virus in Bangladesh
Highly pathogenic H5N1 and low pathogenic H9N2 avian influenza viruses are circulating in Bangladesh since 2007 causing serious economic losses to the country. Multiple virus introductions of different clades of HPAIV H5N1, reassorted genotypes, and on-going diversification of LPAIV H9N2 create a highly volatile virological environment which potentially implicates increased virulence, adaptation to new host species, and subsequent zoonotic transmission.
888
22 Jul 2020
Topic Review
Hepcidin-Ferroportin Interaction Controls Systemic Iron-Homeostasis
Despite its abundance in the environment, iron is poorly bioavailable and subject to strict conservation and internal recycling by most organisms. In vertebrates, the stability of iron concentration in plasma and extracellular fluid, and the total body iron content are maintained by the interaction of the iron-regulatory peptide hormone hepcidin with its receptor and cellular iron exporter ferroportin (SLC40a1). Ferroportin exports iron from duodenal enterocytes that absorb dietary iron, from iron-recycling macrophages in the spleen and the liver, and from iron-storing hepatocytes. Hepcidin blocks iron export through ferroportin, causing hypoferremia. During iron deficiency or after hemorrhage, hepcidin decreases to allow iron delivery to plasma through ferroportin, thus promoting compensatory erythropoiesis. As a host defense mediator, hepcidin increases in response to infection and inflammation, blocking iron delivery through ferroportin to blood plasma, thus limiting iron availability to invading microbes. Genetic diseases that decrease hepcidin synthesis or disrupt hepcidin binding to ferroportin cause the iron overload disorder hereditary hemochromatosis.
887
22 Jun 2021
Topic Review
Meat Quality Perception in Argentina
In Argentina, color and intramuscular fat are the main attributes of raw beef quality; however, it is necessary to clarify how consumers use them, in order to establish different marketing strategies. Consumer preferences are affected by multiple factors. Thus, the objective of the present study was to identify the Argentinian consumer’s choice behavior regarding beef color and fat content. An online survey was carried out in Argentina. It inquired about socio-demographic characteristics, purchase and consumption habits and beliefs, showing pictures related to color, marbling and the amount of fat. Choice behavior was evaluated by asking why consumers chose a particular picture out of the ones shown. Several Kruskal–Wallis tests evaluated the different hypotheses. Three different decision trees using the CHAID analysis method were created. Multifactorial analysis was carried out for clustering consumers. Regarding consumer beliefs, 90% of the respondents agreed with the sentence, “The two main characteristics defining beef quality at purchase time are meat color and marbling”. Socio-demographic characteristics affected purchase habits and beliefs; they also affected perceptions about meat color and marbling. It was possible to build three consumer groups for future marketing strategies: “hedonic” focused on a pleasing sensory experience, “appearance” prioritized the visual aspects, and the “health-conscious” consumers were interested in their healthy nutrition.
887
28 Sep 2021
Topic Review
Fish Protein-Based Gel Products
Texture is an important parameter in determining the quality characteristics and consumer acceptability of seafood and fish protein-based products. The quality of protein gel used in food development depends on its functional and nutritional properties. The number of commercial gel products is growing with the use of different additives, such as monosaccharides, oligosaccharides, polysaccharides and protein-based hydrolysates. The addition of such additives has improved the gelling properties of surimi gel in different ways: (a) by preventing the protein oxidation, denaturation and aggregation; (b) by improving the intermolecular binding interactions; (c) by enhancing the amino acids cross-linking and (d) reducing the amount of free water molecules during processing and preservation.
886
17 Mar 2022
Biography
Walter H. Schottky
Walter Hans Schottky (23 July 1886 – 4 March 1976) was a German physicist who played a major early role in developing the theory of electron and ion emission phenomena,[1] invented the screen-grid vacuum tube in 1915 while working at Siemens,[2] co-invented the ribbon microphone and ribbon loudspeaker along with Dr. Erwin Gerlach in 1924[3] and later made many significant contributions in the
886
21 Nov 2022
Topic Review
5-Hydroxytryptamine and Gut
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is reported to modulate the development and neurogenesis of the enteric nervous system, gut motility, secretion, inflammation, sensation, and epithelial development. Approximately 95% of 5-HT in the body is synthesized and secreted by enterochromaffin (EC) cells, the most common type of neuroendocrine cells in the gastrointestinal (GI) tract, through sensing signals from the intestinal lumen and the circulatory system. Gut microbiota, nutrients, and hormones are the main factors that play a vital role in regulating 5-HT secretion by EC cells. Apart from being an important neurotransmitter and a paracrine signaling molecule in the gut, gut-derived 5-HT was also shown to exert other biological functions (in autism and depression) far beyond the gut. Moreover, studies conducted on the regulation of 5-HT in the immune system demonstrated that 5-HT exerts anti-inflammatory and proinflammatory effects on the gut by binding to different receptors under intestinal inflammatory conditions. Understanding the regulatory mechanisms through which 5-HT participates in cell metabolism and physiology can provide potential therapeutic strategies for treating intestinal diseases. Herein, we review recent evidence to recapitulate the mechanisms of synthesis, secretion, regulation, and biofunction of 5-HT to improve the nutrition and health of humans.
886
17 Aug 2021
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