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Topic Review
Biography
Topic Review
GPR in Wood Structures
Ground penetrating radar (GPR) is a nondestructive inspection tool based upon the electromagnetic (EM) theory that radio wave propagation is governed by the EM properties of a dielectric material. GPR has many characteristics that make it attractive as an inspection tool for wood: it is faster than many acoustic and stress wave techniques; it does not require the use of a couplant; while it can also detect the presence of moisture. Moisture detection is of prime concern, and several researchers have labored to measure internal moisture using GPR.
938
27 May 2021
Topic Review
Management of Pike in Alaska
Northern pike are an invasive species in southcentral Alaska and have caused the decline and extirpation of salmonids and other native fish populations across the region. Northern pike control actions are tailored to the unique conditions of waters prioritized for their management, and all efforts support the goal of preventing further spread of this invasive aquatic apex predator to vulnerable waters.
938
26 Aug 2021
Topic Review
Drought Stress in Grain Legumes
Grain legumes are important sources of proteins, essential micronutrients and vitamins and for human nutrition. Climate change, including drought, is a severe threat to grain legume production throughout the world. The yield loss of grain legumes varies from species to species, even variety to variety within a species, depending upon the severity of drought stress and several other factors, such as phenology, soil textures and agro-climatic conditions. Closure of stomata leads to an increase in leaf temperature by reducing the transpiration rate, and, so, the legume plant faces another stress under drought stress. The biosynthesis of reactive oxygen species (ROS) is the most detrimental effect of drought stress. Legumes can adapt to the drought stress by changing their morphology, physiology and molecular mechanism. Improved root system architecture (RSA), reduced number and size of leaves, stress-induced phytohormone, stomatal closure, antioxidant defense system, solute accumulation (e.g., proline) and altered gene expression play a crucial role in drought tolerance.
938
30 Nov 2021
Topic Review
Autophagy-ER Stress Axis in High Fat/Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease that can progress from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH), and even further to liver cirrhosis or liver cancer. Overconsumption of high fat and/or carbohydrate are among the most common lifestyle factors that drive the development and progression of NAFLD. This review evaluates recent reports on the involvement of autophagy and endoplasmic reticulum (ER) stress in the pathogenesis of NAFLD. Here, we reveal a mechanism of an intrinsically linked axis of impaired autophagy and unresolved ER stress that mediates the development and progression of NAFLD resulting from the overconsumption of high fat and/or carbohydrate.
937
05 Nov 2020
Topic Review
Whisking in Animals
Whisking is a behaviour in which the facial whiskers (vibrissae) of an animal are repetitively and rapidly swept back and forth. This behaviour occurs particularly during locomotion and exploration. The whisking movements occur in bouts of variable duration, and at rates between 3 and 25 whisks/second. Movements of the whiskers are closely co-ordinated with those of the head and body, allowing the animal to locate interesting stimuli through whisker contact, then investigate them further using both the macrovibrissae and an array of shorter, non-actuated microvibrissae on the chin and lips. Whisking has been reported in a wide range of mammals, including two species of marsupial. Whisking contributes both to exploratory movements, which function to acquire sensory inputs, and to palpation movements, which are used in the discrimination of objects and in the control of spatial navigation.
939
03 Nov 2022
Topic Review
The Association between Biofilm Formation and Antimicrobial Resistance
Biofilm has garnered a lot of interest due to concerns in various sectors such as public health, medicine, and the pharmaceutical industry. Biofilm-producing bacteria show a remarkable drug resistance capability, leading to an increase in morbidity and mortality.
937
22 Jul 2022
Biography
Thomas Townsend Brown
Thomas Townsend Brown (March 18, 1905 – October 27, 1985)[1] was an United States inventor whose research into odd electrical effects led him to believe he had discovered a connection between strong electric fields and gravity, a type of antigravity effect. Instead of being an antigravity force, what Brown observed has generally been attributed to electrohydrodynamics, the movement of charged
937
19 Dec 2022
Topic Review
2009 Flu Pandemic Vaccine
The 2009 flu pandemic vaccines were influenza vaccines developed to protect against the pandemic H1N1/09 virus. These vaccines either contained inactivated (killed) influenza virus, or weakened live virus that could not cause influenza. The killed vaccine was injected, while the live vaccine was given as a nasal spray. Both these types of vaccine were produced by growing the virus in chicken eggs. Around three billion doses were produced, with delivery in November 2009.Cite error: Closing missing for tag providing a strong protective immune response and having similar safety profile to the usual seasonal influenza vaccine. However, about 30% of people already had some immunity to the virus, with the vaccine conferring greatest benefit on young people, since many older people are already immune through exposure to similar viruses in the past. The vaccine also provided some cross-protection against the 1918 flu pandemic strain. Early results (pre-25 December 2009) from an observational cohort of 248,000 individuals in Scotland showed the vaccine to be effective at preventing H1N1 influenza (95.0% effectiveness [95% confidence intervals 76.0–100.0%]) and influenza-related hospital admissions (64.7% [95% confidence intervals 12.0–85.8%]). Developing, testing, and manufacturing sufficient quantities of a vaccine is a process that takes many months. According to Keiji Fukuda of the World Health Organization, "There's much greater vaccine capacity than there was a few years ago, but there is not enough vaccine capacity to instantly make vaccines for the entire world's population for influenza." The nasal mist version of the vaccine started shipping on 1 October 2009.
937
17 Oct 2022
Topic Review
Cardiolipin
Cardiolipin (IUPAC name 1,3-bis(sn-3’-phosphatidyl)-sn-glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition. It can also be found in the membranes of most bacteria. The name "cardiolipin" is derived from the fact that it was first found in animal hearts. It was first isolated from beef heart in the early 1940s. In mammalian cells, but also in plant cells, cardiolipin (CL) is found almost exclusively in the inner mitochondrial membrane, where it is essential for the optimal function of numerous enzymes that are involved in mitochondrial energy metabolism.
938
28 Sep 2022
Topic Review
Age-Related Hearing Loss
Age-related hearing impairment, also referred to as presbycusis, is the most common sensory impairment seen in the elderly. As our cochlea, the peripheral organ of hearing, ages, we tend to experience a decline in hearing and are at greater risk of cochlear sensory-neural cell degeneration and exacerbated age-related hearing impairments (e.g., gradual hearing loss, deterioration in speech comprehension, difficulty in the localization sound sources, and ringing sensations in the ears). Here, we outline recent research into major causal factors of age-related hearing loss including both extrinsic (e.g. noise and ototoxic medication), and intrinsic factors (e.g. genetic predisposition, epigenetic factors and aging).
937
23 Oct 2020
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