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Topic Review
The Oral Bacteriome and COVID-19
Metagenomic analysis of the oral bacteriome of patients suffering from COVID-19 have revealed the abundance of cariogenic (tooth decay) and periodontopathic (periodontitis) bacteria. This indicates that changes in the diversity of the oral bacteriome can lead to COVID-19 complications. 
  • 290
  • 17 May 2023
Topic Review
suPAR in Autoimmune Rheumatic Diseases
The soluble urokinase plasminogen activator receptor (suPAR) is the bioactive form of urokinase plasminogen activator receptor (uPAR), a membrane-bound glycoprotein, and it is primarily expressed on the surface of immunologically active cells. Mirroring local inflammation and immune activation, suPAR has gained interest as a potential prognostic biomarker in several inflammatory diseases. Mirroring immune system activation, suPAR has been associated with many autoimmune rheumatic diseases.
  • 302
  • 17 May 2023
Topic Review
Biology of Ixodiphagus spp. and Geographic Distribution
Species within the genus Ixodiphagus (Hymenoptera: Encyrtidae) are natural parasitoid wasps of ticks (Acari: Ixodida), which were first described more than a century ago, in Haemaphysalis leporispalustris from Texas, United States (USA).
  • 497
  • 17 May 2023
Topic Review
Grazing on Animal Productivity and the Environment
Grazing lands provide ecosystem services including regulation and storage of water flows, nutrient cycling, and C sequestration. Livestock grazing is the most important factor shaping and stabilizing pasture biodiversity. Some opportunities for pasture feeding are the health-promoting and nutritional qualities of milk and milk products, especially milk from pasture-fed cows. The beneficial effects of pasture feeding on animal health and welfare are not insignificant. Available organizational innovations can help better manage livestock grazing and, above all, better understand the impact of the grazing process on the environment and climate change.
  • 373
  • 17 May 2023
Topic Review
Hepatitis-B-Virus-Induced Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) remains a global health challenge, causing 600,000 deaths each year. Infectious factors, including hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis D virus (HDV), have long been considered the major risk factors for the development and progression of HCC. These pathogens induce hepatocyte transformation through a variety of mechanisms, including insertional mutations caused by viral gene integration, epigenetic changes, and the induction of long-term immune dysfunction.
  • 336
  • 17 May 2023
Topic Review
Applications of Bioprinting on Pathological Liver Models
Significant progress has been made in liver tissue engineering through the use of 3D bioprinting technology. This technology offers the ability to create personalized biological structures with precise geometric design capabilities. The complex and multifaceted nature of liver diseases underscores the need for advanced technologies to accurately mimic the physiological and mechanical characteristics, as well as organ-level functions, of liver tissue in vitro. Bioprinting stands out as a superior option over traditional two-dimensional cell culture models and animal models due to its stronger biomimetic advantages.
  • 307
  • 17 May 2023
Topic Review
Harnessing the Power of AI for Modern Agriculture
Agriculture is a critical component of our global economy and food security. Fortunately, AI has the potential to revolutionize modern agriculture and help us meet the challenges of feeding a growing population while minimizing the environmental impact of farming. How AI can be used to optimize crop yields, improve resource efficiency, enhance pest and disease management, and support sustainable farming practices were described here.
  • 498
  • 17 May 2023
Topic Review
Physicochemistry of Deep Eutectic Solvents
Deep eutectic solvents (DESs), considered as one of the greenest families of solvents, are used in many fields, such as organic synthesis, (bio)catalysis, electrochemistry, and (bio)medicine.
  • 512
  • 17 May 2023
Topic Review
Epstein–Barr Virus and Lymphomagenesis
The clinical significance of Epstein–Barr virus (EBV) cannot be understated. Not only does it infect approximately 90% of the world’s population, but it is also associated with numerous pathologies. Diseases linked to this virus include hematologic malignancies such as diffuse large B-cell lymphoma, Hodgkin lymphoma, Burkitt lymphoma, primary CNS lymphoma, and NK/T-cell lymphoma, epithelial malignancies such as nasopharyngeal carcinoma and gastric cancer, autoimmune diseases such as multiple sclerosis, Graves’ disease, and lupus. While treatment for these disease states is ever evolving, much work remains to more fully elucidate the relationship between EBV, its associated disease states, and their treatments.
  • 238
  • 17 May 2023
Topic Review
Allelochemicals from Microalgae
Allelochemicals are toxic secondary metabolites produced by plants, microalgae, bacteria, and fungi that influence other organisms. The bioactivity of allelochemicals and their toxic or beneficial effects have been the focus of research in medicine and agriculture, and for their anticancer and antimicrobial properties. Microalgae are the source of a remarkable diversity of biologically active compounds, which can be involved in allelopathic interactions. The main chemical classes of microalgal allelochemicals are alkaloids, fatty acids and derivatives, polyketides, peptides, phenolics, and terpenoids. In the environment, these molecules are secreted by microalgae for communication, defence, and adaptation purposes.
  • 415
  • 17 May 2023
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