Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Vitamin D-dependent Rickets
Vitamin D-dependent rickets is a disorder of bone development that leads to softening and weakening of the bones (rickets).
  • 1.0K
  • 23 Dec 2020
Topic Review
Hepatitis B Virus Infection Understanding
Chronic hepatitis B virus (HBV) infection affects 292 million people worldwide and is associated with a broad range of clinical manifestations including cirrhosis, liver failure, and hepatocellular carcinoma (HCC). Despite the availability of an effective vaccine HBV still causes nearly 900,000 deaths every year. Current treatment options keep HBV under control, but they do not offer a cure as they cannot completely clear HBV from infected hepatocytes. The recent development of reliable cell culture systems allowed for a better understanding of the host and viral mechanisms affecting HBV replication and persistence. Recent advances into the understanding of HBV biology, new potential diagnostic markers of hepatitis B infection, as well as novel antivirals targeting different steps in the HBV replication cycle are summarized in this review article.
  • 1.0K
  • 29 Sep 2020
Topic Review
Probiotics in cosmetics
Probiotics, defined as “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host,” are becoming increasingly popular and marketable. The cosmetic industry has harnessed this potential by producing products claiming to contain probiotics. However, not all products marketed as such comply with the requirements for this claim.  
  • 1.0K
  • 10 Mar 2021
Topic Review
Glycosylation
Post-translational modifications are one way that biomineral-associated cells control the function and fate of proteins. Of the ten different types of post-translational modifications, one of the most interesting and complex is glycosylation, or the covalent attachment of carbohydrates to amino acid sidechains Asn, Ser, and Thr of proteins. There are several biomineral-associated glycoproteins that have been characterized, and a subset of these have been the subject of intensive in vitro experimentation.  These studies indicate that glycosylation does not alter the inherent function of the biomineralization protein; rather, it either accentuates or attenuates protein functionality. In essence, glycosylation gives the cell the “last word” as to what degree a biomineralization protein will participate in the biomineralization process.
  • 1.0K
  • 25 Sep 2020
Topic Review
Mycobacterium avium Complex
Slow-growing mycobacteria, Mycobacterium avium, and rapid-growing mycobacteria, Mycobacterium abscessus, are important emerging human pathogens causing disease in vulnerable populations such as severelyimmunocompromised patients, patients with chronic lung diseases, and others with underlying health conditions. Their incidence is increasing worldwide in industrialized countries and they cause substantial yet underacknowledged burden of disease. An overview of the general characteristics, vulnerable populations most at risk, pathogenesis, treatment, and prevention for infections caused by Mycobacterium avium, in the context of MAC, and M. abscessus are presented in this review.
  • 1.0K
  • 14 Aug 2020
Topic Review
Soybean Isoflavones
Soybeans are rich in proteins and lipids and have become a staple part of the human diet. Besides their nutritional excellence, they have also been shown to contain various functional components, including isoflavones, and have consequently received increasing attention as a functional food item. Isoflavones are structurally similar to 17-β-estradiol and bind to estrogen receptors (ERα and ERβ). The estrogenic activity of isoflavones ranges from a hundredth to a thousandth of that of estrogen itself. Isoflavones play a role in regulating the effects of estrogen in the human body, depending on the situation. Thus, when estrogen is insufficient, isoflavones perform the functions of estrogen, and when estrogen is excessive, isoflavones block the estrogen receptors to which estrogen binds, thus acting as an estrogen antagonist. In particular, estrogen antagonistic activity is important in the breast, endometrium, and prostate, and such antagonistic activity suppresses cancer occurrence. 
  • 1.0K
  • 06 Jul 2021
Topic Review Peer Reviewed
Otovestibular Symptoms of COVID-19 and Its Vaccines/Treatments
The rapidly developing literature regarding COVID-19 and its treatments has documented an impressive breadth of pathology across multiple organ systems. In this entry, researchers highlight the audiologic and vestibular manifestations that have been reported in association with COVID-19, its vaccines, and some of its treatments.
  • 1.0K
  • 08 Jul 2022
Topic Review
Transposable Elements
Transposable elements (TEs) are mobile DNA sequences that can jump from one genomic locus to another and that have colonized the genomes of all living organisms. While TE mobilization is an important source of genomic innovations that greatly contribute to the host species evolution, it is also a major threat to genome integrity that can lead to pathologies.
  • 1.0K
  • 26 May 2022
Topic Review
Non-Amyloidbeta-Tau Biomarkers
Core biomarkers amyloid beta (Aβ) and Tau have been considered as key neuropathological hallmarks of Alzheimer's disease. However, they did not sufficiently reflect clinical severity and therapeutic response, proving the difficulty of the Aβ- and Tau-targeting therapies in clinical trials. Along with these core biomarkers, non-Amyloidbeta-Tau pathophysiological biomarkers (Neurodegeneration-related biomarkers, biomarkers for neuroinflammation and phagocytosis of an innate immune system, lipid metabolism biomarkers) could serve as advanced reporters for early diagnosing AD, predicting AD progression, and monitoring the treatment response.
  • 1.0K
  • 18 Nov 2020
Topic Review
Endophytic Bacterial in Rice Plant
Endophytic bacterial communities are beneficial communities for host plants that exist inside the surfaces of plant tissues, and their application improves plant growth. They benefit directly from the host plant by enhancing the nutrient amount of the plant’s intake and influencing the phytohormones, which are responsible for growth promotion and stress. Endophytic bacteria play an important role in plant-growth promotion (PGP) by regulating the indirect mechanism targeting pest and pathogens through hydrolytic enzymes, antibiotics, biocontrol potential, and nutrient restriction for pathogens. 
  • 1.0K
  • 15 Oct 2021
  • Page
  • of
  • 1814
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Video Production Service
Feedback