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Topic Review
Ginseng against Respiratory Tract Infections
Ginseng has been reported to inhibit bacterial pathways, thereby killing bacteria indirectly. It has also been shown to protect the host from bacterial invasion.
  • 1.1K
  • 30 Sep 2021
Topic Review
Animal and Plant Protein Oxidation
Protein oxidation, a phenomenon that was not well recognized previously but now better under-stood, is a complex chemical process occurring ubiquitously in food systems and can be induced by processing treatments as well. While early research concentrated on muscle protein oxidation, later investigations included plant, milk, and egg proteins. The process of protein oxidation involves both radicals and nonradicals, and amino acid side chain groups are usually the site of initial oxidant attack which generates protein carbonyls, disulfide, dityrosine, and protein radicals. The ensuing alteration of protein conformational structures and formation of protein polymers and aggregates can result in significant changes in solubility and functionality, such as gelation, emulsification, foaming, and water-holding. Oxidant dose-dependent effects have been widely reported, i.e., mild-to-moderate oxidation may enhance the functionality while strong oxidation leads to insolubilization and functionality losses. Therefore, controlling the extent of protein oxidation in both animal and plant protein foods through oxidative and antioxidative strategies has been of wide interest in model system as well in in situ studies.
  • 1.1K
  • 13 Jan 2021
Topic Review
African Swine Fever Virus
African swine fever virus (ASFV) is the causative agent of the epidemic of African swine fever (ASF), with virulent strains having a mortality rate of up to 100% and presenting devastating impacts on animal farming. ASFV is the only known arbovirus in the Nucleoplasmic Large DNA Virus (NCLDV) family. It has an icosahedral structure and envelope with a diameter of 200nm. The length of the genome varies between 170 and 190 kbp, encoding 151 to 167 open reading frames (ORF), which are closely spaced along two strands of viral DNA and separated by short intergenic regions.
  • 1.1K
  • 09 Mar 2022
Topic Review
Marek’s Disease Outbreak in Asia
Marek’s disease is an infectious disease in poultry that usually appears in neural and visceral tumors. This disease is caused by Gallid alphaherpesvirus 2 infection in lymphocytes, and its meq gene is commonly used in virulent studies for coding the key protein functional in oncogenic transformation of the lymphocytes. Although vaccines have been introduced in many countries to control its spread and are proven to be efficient, recent records show a decline of such efficiency due to viral evolution. 
  • 1.1K
  • 11 Mar 2022
Biography
Avi Loeb
Abraham "Avi" Loeb (Hebrew: אברהם (אבי) לייב‎; born February 26, 1962) is an Israeli-United States theoretical physicist who works on astrophysics and cosmology. Loeb is the Frank B. Baird Jr. Professor of Science at Harvard University. He had been the longest serving Chair of Harvard's Department of Astronomy (2011–2020), Founding Director of Harvard's Black Hole Initiative (sin
  • 1.1K
  • 17 Nov 2022
Topic Review
Health-Promoting Effects of Mango Fruit
Mango (Mangifera indica L.), known as the king of fruits, has an attractive taste and fragrance and high nutritional value. Mango is commercially important in India, where ~55% of the global crop is produced. The fruit has three main parts: pulp, peel, and kernel. The pulp is the most-consumed part, while the peel and kernel are usually discarded. Mango pulp is a source of a variety of reducing sugars, amino acids, aromatic compounds, and functional compounds, such as pectin, vitamins, anthocyanins, and polyphenols. 
  • 1.1K
  • 19 May 2021
Topic Review
IL-10 in Neurodegenerative Diseases
IL-10, an immunosuppressive cytokine, is considered an important anti-inflammatory modulator of glial activation, preventing inflammation-mediated neuronal degeneration under pathological conditions. In this narrative review, we summarize recent insights about the role of IL-10 in the neurodegeneration associated with neuroinflammation, in diseases such as Multiple Sclerosis, Traumatic Brain Injury, Amyotrophic lateral sclerosis, Alzheimer's Disease, and Parkinson's Disease, focusing on the contribution of this cytokine not only in terms of protective action, but also as possibly responsible for clinical worsening. The knowledge of this double face of the same coin, regarding the biological role of the IL-10, could aid the development of targeted therapies useful for limiting neurodegenerative processes.
  • 1.1K
  • 17 Jul 2020
Topic Review
AI&ML for Medical Sector
This work represents a comprehensive analysis of the potential AI, ML, and IoT technologies for defending against the COVID-19 pandemic. The existing and potential applications of AI, ML, and IoT, along with a detailed analysis of the enabling tools and techniques are outlined. A critical discussion on the risks and limitations of the aforementioned technologies are also included.
  • 1.1K
  • 21 Jan 2021
Topic Review
CLIP
CLIP (cross-linking immunoprecipitation) is a method used in molecular biology that combines UV cross-linking with immunoprecipitation in order to analyse protein interactions with RNA or to precisely locate RNA modifications (e.g. m6A). CLIP-based techniques can be used to map RNA binding protein binding sites or RNA modification sites of interest on a genome-wide scale, thereby increasing the understanding of post-transcriptional regulatory networks.
  • 1.1K
  • 21 Oct 2022
Topic Review
Amaryllidaceae Alkaloids
Alkaloids are an important group of specialized nitrogen metabolites with a wide range of biochemical and pharmacological effects. Since the first publication on lycorine in 1877, more than 650 alkaloids have been extracted from Amaryllidaceae bulbous plants and clustered together as the Amaryllidaceae alkaloids (AAs) family. 
  • 1.1K
  • 31 May 2021
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