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Topic Review
Stellate Ganglia and Cardiac Sympathetic Overactivation
Heart failure (HF) is a major public health problem worldwide, especially coronary heart disease (myocardial infarction)-induced HF with reduced ejection fraction (HFrEF), which accounts for over 50% of all HF cases. An estimated 6 million American adults have HF. As a major feature of HF, cardiac sympathetic overactivation triggers arrhythmias and sudden cardiac death, which accounts for nearly 50–60% of mortality in HF patients. Regulation of cardiac sympathetic activation is highly integrated by the regulatory circuitry at multiple levels, including afferent, central, and efferent components of the sympathetic nervous system. Much evidence has confirmed the afferent and central neural mechanisms causing sympathoexcitation in HF. The stellate ganglion is a peripheral sympathetic ganglion formed by the fusion of the 7th cervical and 1st thoracic sympathetic ganglion. As the efferent component of the sympathetic nervous system, cardiac postganglionic sympathetic neurons located in stellate ganglia provide local neural coordination independent of higher brain centers. 
  • 661
  • 21 Nov 2022
Biography
Stefan Ślopek
Stefan Ślopek (December 1, 1914 in Skawa near Kraków – 22 August 1995, Wrocław[1] was a Polish scientist specializing in clinical microbiology and immunology. He is the great grandson of Józef Juraszek Ślopek. He is buried in the Grabiszyński Cemetery in Wrocław. After he had completed his secondary education in Tarnopol, he started his medical studies at the Faculty of Medicine in
  • 407
  • 27 Dec 2022
Topic Review
Steelhead Trout
Steelhead Trout is a name given to the anadromous form of the coastal rainbow trout (Oncorhynchus. m. irideus) or redband trout (O. m. gairdneri). The steelhead are native to freshwater and ocean environments across North America, but have been introduced to every other continent except Antarctica. Steelhead use aquatic obstructions like vegetation, boulders, and fallen trees as protection. Steelhead migrate to spawn during the summer months and the winter months.
  • 587
  • 14 Oct 2022
Topic Review
STEC-HUS Therapeutic Strategies
Shiga toxin-producing Escherichia coli (STEC)-associated hemolytic uremic syndrome (STEC-HUS) is a clinical syndrome involving hemolytic anemia (with fragmented red blood cells), low levels of platelets in the blood (thrombocytopenia), and acute kidney injury (AKI). It is the major infectious cause of AKI in children. In severe cases, neurological complications and even death may occur. Treating STEC-HUS is challenging, as patients often already have organ injuries when they seek medical treatment.
  • 298
  • 13 Mar 2023
Topic Review
Steatohepatitis, Mitochondria, and Inflammasome
Alcoholic (ASH) and nonalcoholic steatohepatitis (NASH) are advanced stages of fatty liver disease and two of the most prevalent forms of chronic liver disease. ASH and NASH are associated with significant risk of further progression to cirrhosis and hepatocellular carcinoma (HCC), the most common type of liver cancer, and a major cause of cancer-related mortality. Mitochondrial damage and activation of inflammasome complexes have a role in inducing and sustaining liver damage.
  • 313
  • 25 May 2022
Topic Review
Steatocystoma Multiplex
Steatocystoma multiplex is a skin disorder characterized by the development of multiple noncancerous (benign) cysts known as steatocystomas.
  • 630
  • 23 Dec 2020
Topic Review
Steam Explosion Technology in Modification of Food Fiber
Steam explosion is a widely used hydrothermal pretreatment method, also known as autohydrolysis, which has become a popular pretreatment method due to its lower energy consumption and lower chemical usage. Steam explosion (SE) technology is a new type of physicochemical modification technology of food raw materials. SE is a method that presses high-pressure and high-temperature steam into cell walls and plant tissues, applying the thermochemical action of high-temperature cooking coupled with the physical tearing action of instantaneous blasting.
  • 525
  • 07 Dec 2022
Topic Review
Stazione Zoologica
The Stazione Zoologica Anton Dohrn is a research institute in Naples, Italy, devoted to basic research in biology. Research is largely interdisciplinary involving the fields of evolution, biochemistry, molecular biology, neurobiology, cell biology, biological oceanography, marine botany, molecular plant biology, benthic ecology, and ecophysiology. Founded in 1872 as a private concern by Anton Dohrn, in 1982 the Stazione Zoologica came under the supervision and control of the Ministero dell'Università e della Ricerca Scientifica e Tecnologica (Ministry of Universities and Scientific and Technological Research) as a National Institute.
  • 868
  • 26 Oct 2022
Topic Review
Status of Cardiovascular Inflammatory Diseases
The diagnosis of myocardial injury inflammatory lesions is a difficult and challenging task, and despite various imaging modalities, myocardial injury inflammatory lesions are still a diagnosis of exclusion. Currently, endomyocardial biopsy (EMB) combined with genomics and immunohistochemistry can be used to evaluate myocardial inflammatory lesions in clinical practice. However, due to its invasiveness, sampling variability, limited spatial information, and low clinical implementation, it is difficult to apply in clinical practice and has great limitations. For inflammatory lesions of myocardium injury, clinical treatment strategies are supportive treatment or treatment of the primary underlying diseases, which are focused on delaying the disease process, are unable to reverse and repair the myocardial injury, and have limited effects on reducing morbidity and mortality. Therefore, it is of clinical urgency to actively seek effective treatment methods for myocardial injury and inflammation.
  • 298
  • 24 Apr 2022
Topic Review
Status and Needs of Shark Conservation
The expanding shark fin market has resulted in intensive global shark fishing. With 90% of teleost fish stocks over-exploited, sharks have become the most lucrative target. As predators, they have high ecological value, are sensitive to fishing pressure, and are in decline, but the secretive nature of the fin trade and difficulties obtaining relevant data, obscure their true status. In consumer countries, shark fin is a luxury item and rich consumers pay high prices with little interest in sustainability or legal trade. Thus, market demand will continue to fuel the hunt for sharks and those accessible to fishing fleets are increasingly endangered. Current legal protections are not working, as exemplified by the case of the shortfin mako shark. Claims that sharks can be sustainably fished under these circumstances are misguided. To avert a catastrophic collapse across the planet’s aquatic ecosystems, sharks and their habitats must be given effective protection. 
  • 493
  • 21 Sep 2022
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