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Topic Review
Tea Tree Oil Induced Resistance
The essential tea tree oil (TTO) derived from Melaleuca alternifolia plant is widely used as a biopesticide to protect crops from several plant-pathogens. TTO was approved by the European Union (EU) and included in the positive list of the EU, in Annex I of Directive 91/414/EEC for registration of Plant Protection Products. TTO is classified as a low risk substance in Europe. This oil is in large use in cosmetics and in medicine.
  • 998
  • 23 Oct 2020
Topic Review
Tea EGCG and Coffee CGA
Tea and coffee are consumed worldwide and epidemiological and clinical studies have shown their health beneficial effects, including anti-cancer effects. Epigallocatechin gallate (EGCG) and chlorogenic acid (CGA) are the major components of green tea polyphenols and coffee polyphenols, respectively, and believed to be responsible for most of these effects. Although a large number of cell-based and animal experiments have provided convincing evidence to support the anti-cancer effects of green tea, coffee, EGCG, and CGA, human studies are still controversial and some studies have suggested even an increased risk for certain types of cancers such as esophageal and gynecological cancers with green tea consumption and bladder and lung cancers with coffee consumption. 
  • 2.8K
  • 20 Oct 2020
Topic Review
Tea and Its Active Constituents in Cosmetics
Tea plant itself and its extracts together with their centuries-old tradition of use play an important role on the cosmetics market. In general, cosmetics products containing tea extracts rich in polyphenols have a positive effect on the skin appearance and ameliorate skin damage, erythema and lipid peroxidation following UV exposure.
  • 1.3K
  • 29 Mar 2022
Topic Review
TDP-43 Role in Chromatin Remodeling and Transcription
TDP-43 gained momentum in the neurodegeneration field when it was first discovered that almost all amyotrophic lateral sclerosis (ALS) cases and as many as half of frontotemporal dementia (FTD) cases present pathological ubiquitinated inclusions of TDP-43. Its involvement in chromatin silencing and nuclear/cytoplasmic shuttling constitute convergent key findings from several biological screens, and several crucial epigenetic factors appear to be able to modify TDP-43-induced degeneration. TDP-43 activity at the chromatin level and its implication in the regulation of DNA transcription and stability -such as DNA repair and regulation of retrotransposons activity- are further supported by a continuously growing amount of studies.
  • 668
  • 19 Sep 2023
Topic Review
TCTP, Cell Biology and Disease
Translationally controlled tumour protein (TCTP) is multifunctional protein expressed in essentially all eukaryotic organisms. It is a cytoprotective protein that is involved in many basic biological processes, such as cellular stress responses, growth and development. Dysregulation of TCTP occurs in various disease processes, and recently the participation of TCTP in several cancer-promoting pathways has been unveiled. Understanding the core biological functions of TCTP, the mechanisms underlying its cellular regulation and its participation in disease processes is essential for the design of effective anti-cancer strategies that may involve targeting of TCTP.  To provide a current overview of the knowledge in this area, we published a review article in Cells, which represents a detailed compilation of the recent progress in this field . Here, we give a brief overview on the core findings that are reported in this article.
  • 629
  • 27 Oct 2020
Topic Review
TCOF1 Gene
Treacle ribosome biogenesis factor 1: The TCOF1 gene provides instructions for making a protein called treacle.
  • 468
  • 24 Dec 2020
Topic Review
TCN2 Gene
Transcobalamin 2: The TCN2 gene provides instructions for making a protein called transcobalamin (formerly known as transcobalamin II).
  • 458
  • 24 Dec 2020
Topic Review
TCIRG1 Gene
TCIRG1 Gene: T cell immune regulator 1, ATPase H+ transporting V0 subunit a3. The TCIRG1 gene provides instructions for making one part, the a3 subunit, of a large protein complex known as a vacuolar H+-ATPase (V-ATPase).
  • 460
  • 24 Dec 2020
Topic Review
TCHH Gene
Trichohyalin: The TCHH gene provides instructions for making a protein called trichohyalin. This protein is primarily found in hair follicles, which are specialized structures in the skin where hair growth occurs.
  • 789
  • 24 Dec 2020
Topic Review
TCF4 Gene
Transcription factor 4: The TCF4 gene provides instructions for making a protein that attaches (binds) to specific regions of DNA and helps control the activity of many other genes.
  • 391
  • 24 Dec 2020
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