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Topic Review
Use of Propolis in Sustainable Agriculture
Propolis, also known as “bee glue”, is a resinous substance collected by honeybees from various plant sources. For centuries, propolis has been valued for its medicinal properties, primarily in human health applications.  The effectiveness of propolis in controlling common pests and diseases that affect crops, suppressing postharvest illnesses of fruits and vegetables, stimulating plant defenses and increasing stress resistance, is reviewed herein.
  • 275
  • 08 Dec 2023
Topic Review
Vomeronasal System in Mammals
The vomeronasal system (VNS) or accessory olfactory system is specialized in detecting chemical signals, primarily pheromones, kairomones, and molecules from the major histocompatibility complex.
  • 573
  • 08 Dec 2023
Topic Review
Molecular Basis of Cardiometabolic Calpain Isozymes and Calpastatin
Calpain is defined as a member of the superfamily of cysteine proteases possessing the CysPC motif within the gene. Calpain-1 and -2, which are categorized as conventional isozymes, execute limited proteolysis in a calcium-dependent fashion. Accordingly, the calpain system participates in physiological and pathological phenomena, including cell migration, apoptosis, and synaptic plasticity.
  • 187
  • 07 Dec 2023
Topic Review
Maillard Conjugation using Alternative Processing Technologies
Conjugation of the proteins with carbohydrates, occurring in the early stages of the Maillard reactions, received increased attention because of the high potential to ensure the improvement of the biological activity and functional properties of the proteins of different origins.
  • 164
  • 07 Dec 2023
Topic Review
Oxidative Stress in Cirrhosis and Portal Hypertension
Oxidative stress is an imbalance between the production of reactive oxygen species (ROS) and the antioxidant system reducing its capability to detoxify ROS or repair the resulting damage, i.e., ROS overwhelms antioxidants. Oxidative stress is a key pathogenic factor in chronic liver injury of various etiologies, such as alcoholic liver disease.
  • 306
  • 07 Dec 2023
Topic Review
Extended-Spectrum β-Lactamases
The rise of antimicrobial resistance, particularly from extended-spectrum β-lactamase producing Enterobacteriaceae (ESBL-E), poses a significant global health challenge as it frequently causes the failure of empirical antibiotic therapy, leading to morbidity and mortality. The E. coli- and K. pneumoniae-derived CTX-M genotype is one of the major types of ESBL. Mobile genetic elements (MGEs) are involved in spreading ESBL genes among the bacterial population. Due to the rapidly evolving nature of ESBL-E, there is a lack of specific standard examination methods. Carbapenem has been considered the drug of first choice against ESBL-E. 
  • 1.2K
  • 07 Dec 2023
Topic Review
Genomics
A genome is an organism’s comprehensive collection of nucleic acids (DNA or RNA), which contains all of its genes. Genomic science or genomics is the study of the genome’s structure, function, evolution, mapping and modifications. 
  • 379
  • 07 Dec 2023
Topic Review
Role of Leukocytes in Prostate Cancer
Prostate cancer (PCa) remains a significant global health concern, being a major cause of cancer morbidity and mortality worldwide. Furthermore, profound understanding of the disease is needed. Prostate inflammation caused by external or genetic factors is a central player in prostate carcinogenesis.
  • 140
  • 07 Dec 2023
Topic Review
Sheep Meat Processed Products
A concise review of the origin and type of the most important sheep and goat processed meat products produced in different countries and world regions is made. The manuscript also summarizes the most recent studies on sheep and goat processed meats on the physicochemical characterizations, sensory quality, microbiological quality and safety. Some conclusions and future trends in production, processing and commercial potentiality for sheep and goat processed meat products are discussed.
  • 3.6K
  • 06 Dec 2023
Topic Review
Honey Therapy in Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) are considered a major problem for public health, leading to high rates of lower-limb amputations. Moreover, due to the high prevalence rate of predisposing factors, the incidence rate of DFU is still rising. Although DFUs are complex in nature, foot ulceration usually precedes diabetic foot amputations. These impaired chronic wounds usually promote a microbial biofilm, commonly characterized by the presence of multidrug-resistant microorganisms, hampering the efficacy of conventional antibiotic treatments. Honey has been shown to be an effective antibacterial component, including against multidrug-resistant bacteria. Honey’s physical–chemical characteristics, such as the presence of hydrogen peroxide, its low pH levels, and its high sugar and phenolic contents, promote anti-inflammatory and antioxidative activities, improving wound healing.
  • 239
  • 06 Dec 2023
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