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Topic Review
Plant Metabolomics
Plant metabolomics plays important roles in both basic and applied studies regarding all aspects of plant development and stress responses. With the improvement of living standards, people need high quality and safe food supplies. Thus, understanding the pathways involved in the biosynthesis of nutritionally and healthily associated metabolites in plants and the responses to plant-derived biohazards in humans is of equal importance to meet people’s needs. For each, metabolomics has a vital role to play, which is discussed in detail in this study. In addition, the core elements of plant metabolomics are highlighted, researches on metabolomics-based crop improvement for nutrition and safety are summarized, metabolomics studies on plant natural products including traditional Chinese medicine (TCM) for health promotion are briefly presented. Challenges are discussed and future perspectives of metabolomics as one of the most important tools to promote human nutrition and health are proposed.
  • 1.0K
  • 11 May 2021
Topic Review
Sperm Sex-Sorting
The utilization of sex-sorted sperm for artificial insemination and in-vitro fertilization is considered a valuable tool for improving production efficiency and optimizing reproductive management in farm animals, subsequently ensuring sufficient food resource for the growing human population. 
  • 1.0K
  • 29 Apr 2021
Topic Review
RT-qPCR HEV RNA
Hepatitis E virus (HEV) is a non-enveloped single-stranded positive-sense RNA virus, belonging to the Hepeviridae family, resistant to environmental conditions, and transmitted by the consumption of contaminated water. This virus is responsible for both sporadic and epidemic outbreaks, leading to thousands of infections per year in several countries, and is thus considered an emerging disease in Europe and Asia. This study refers to a survey in Portugal during 2019, targeting the detection and eventual quantification of enteric viruses in samples from surface and drinking water. Samples positive for HEV RNA were recurrently found by reverse transcription quantitative PCR (RT-qPCR), in both types of matrix. Our results evidenced the existence of samples positive either for HEV RNA (77.8% in surface water and 66.7% in drinking water) or for infectious HEV (23.0% in surface water and 27.7% in drinking water). These results highlight the need for effective virological control of water for human consumption and activities.
  • 1.0K
  • 04 Feb 2022
Topic Review
Cadmium in Plants
Cd is a naturally occurring environmental toxicant, which is easily absorbed and accumulated by plants, and has strong teratogenic and mutagenic effects on organisms. Human exposure to Cd for a long time can easily cause diseases such as osteoporosis and kidney damage. It is also positively correlated with the outbreak of a variety of cancers, and is classified as a human carcinogen by the International Agency for Research on Cancer (Group I). A large amount of data shows that the intake of Cd in the human body is mainly from the diet. Therefore, it is very important to understand the influx and transport mechanism of Cd in plants.
  • 1.0K
  • 17 Feb 2022
Topic Review
Oldest People
This is a list of tables of the oldest people in the world in ordinal ranks. To avoid including false or unconfirmed claims of extreme old age, names here are restricted to those people whose ages have been validated by an international body that specifically deals in longevity research, such as the Gerontology Research Group (GRG) or Guinness World Records (GWR), and others who have otherwise been reliably sourced. According to this criterion, the longest human lifespan is that of Jeanne Calment of France (1875–1997), who lived to the age of 122 years, 164 days. She met Vincent van Gogh when she was 12 or 13. She received news media attention in 1985, after turning 110. Subsequent investigation found documentation for Calment's age, beyond any reasonable question, in the records of her native city, Arles, France. More evidence of Calment's lifespan has been produced than for any other supercentenarian, such that her case serves as an archetype in the methodology for verifying the ages of the world's oldest people. As women live longer than men on average, combined records for both sexes are predominated by women. The longest undisputed lifespan for a man is that of Jiroemon Kimura of Japan (1897–2013), who died at age 116 years, 54 days. Since the death of 117-year-old Chiyo Miyako of Japan on 22 July 2018, 115-year-old Kane Tanaka, also of Japan, born 2 January 1903, is the oldest living person in the world whose age has been documented. Since the death of 113-year-old Francisco Núñez Olivera of Spain on 29 January 2018, 113-year-old Masazō Nonaka of Japan, born 25 July 1905, is the world's oldest verified living man.
  • 1.0K
  • 30 Nov 2022
Topic Review
GOLPH3, a PI(4)P Binding Protein
Golgi phosphoprotein 3 (GOLPH3), a Phosphatidylinositol 4-Phosphate [PI(4)P] effector at the Golgi, is required for several intracellular functions, including Golgi ribbon structure maintenance, Golgi glycosylation and vesicle trafficking. It is amplified in several solid tumor types and its overexpression correlates with poor prognosis. GOLPH3 influences tumorigenesis through (i) regulation of Golgi-to-plasma membrane trafficking; (ii) turnover and glycosylation of cancer-relevant glycoproteins; (iii) influence on DNA damage response and maintenance of genomic stability.
  • 1.0K
  • 27 Oct 2020
Biography
Guillaume Amontons
Guillaume Amontons (31 August 1663 – 11 October 1705) was a French scientific instrument inventor and physicist. He was one of the pioneers in studying the problem of friction, that is the resistance to motion where bodies are in contact. Guillaume was born in Paris, France. His father was a lawyer from Normandy who had moved to the French capital. While still young, Guillaume lost his hear
  • 1.0K
  • 01 Dec 2022
Topic Review
Nanoparticles in Plants Abiotic Stress Management
Abiotic stress in plants is one of the main obstacles to global agricultural production and food security. Therefore, there is a need for the development of novel approaches to overcome these problems and achieve sustainability. Nanotechnology has emerged as one such novel approach to improve crop production, through the utilization of nanoscale products, such as nanofertilizer, nanofungicides, nanoherbicides and nanopesticides. Their ability to cross cellular barriers makes nanoparticles suitable for their application in agriculture. Since they are easily soluble, smaller, and effective for uptake by plants, nanoparticles are widely used as a modern agricultural tool. The implementation of nanoparticles has been found to be effective in improving the qualitative and quantitative aspects of crop production under various biotic and abiotic stress conditions.
  • 1.0K
  • 27 Feb 2023
Topic Review Peer Reviewed
The Apicomplexan Parasite Toxoplasma gondii
Toxoplasma gondii  is a ubiquitous zoonotic parasite with an obligatory intracellular lifestyle. It relies on a specialized set of cytoskeletal and secretory organelles for host cell invasion. When infecting its felid definitive host, T. gondii  undergoes sexual reproduction in the intestinal epithelium, producing oocysts that are excreted with the feces and sporulate in the environment. In other hosts and/or tissues, T. gondii  multiplies by asexual reproduction. Rapidly dividing tachyzoites expand through multiple tissues, particularly nervous and muscular tissues, and eventually convert to slowly dividing bradyzoites which produce tissue cysts, structures that evade the immune system and remain infective within the host. Infection normally occurs through ingestion of sporulated oocysts or tissue cysts. While T. gondii  is able to infect virtually all warm-blooded animals, most infections in humans are asymptomatic, with clinical disease occurring most often in immunocompromised hosts or fetuses carried by seronegative mothers that are infected during pregnancy.
  • 1.0K
  • 18 Apr 2022
Topic Review
Spermine
In recent years, research on spermine (Spm) has turned up a lot of new information about this essential polyamine, especially as it is able to counteract damage from abiotic stresses. Spm has been shown to protect plants from a variety of environmental insults, but whether it can prevent the adverse effects of drought has not yet been reported. Drought stress increases endogenous Spm in plants and exogenous application of Spm improves the plants’ ability to tolerate drought stress. Spm's role in enhancing antioxidant defense mechanisms, glyoxalase systems, methylglyoxal (MG) detoxification, and creating tolerance for drought-induced oxidative stress is well documented in plants. However, the influences of enzyme activity and osmoregulation on Spm biosynthesis and metabolism are variable. Spm interacts with other molecules like nitric oxide (NO) and phytohormones such as abscisic acid, salicylic acid, brassinosteroids, and ethylene, to coordinate the reactions necessary for developing drought tolerance. This review focuses on the role of Spm in plants under severe drought stress. We have proposed models to explain how Spm interacts with existing defense mechanisms in plants to improve drought tolerance.
  • 1.0K
  • 23 Feb 2021
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