Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Vitamin C and Kidney Injury
Vitamin C is an important micronutrient and antioxidant for the human body.  In animal experiments, it can protect the kidneys from injury caused by nephrotoxic drugs.  A major feature of COVID-19 and similar viral infection is the cytokine storm, which causes a rise of multiple cytokines in the blood. Those cytokines result in the oxidative stress in cells, which leads to damage to organs and tissues, including the kidneys.  Here, we reviewed the current literature on kidney damage in COVID-19 patients and analyzed the possible etiology and mechanisms.  In addition, we summarized the potential use of vitamin C in preventing kidney damage in experimental animal models and the underlying mechanisms.  Vitamin C appears to protect and facilitate recovery of kidneys from injuries derived from excessive of oxidative stress, a feature of cytokines storm in people with COVID-19.  Finally, we would like to argue that vitamin C may be protective of the renal functions in COVID-19 patients with pre-existing kidney diseases. 
  • 1.1K
  • 26 Jul 2021
Topic Review
Oxidative Stress in Obesity
Adipose tissue (AT) storage capacity is central in the maintenance of whole-body homeostasis, especially in obesity states. However, sustained nutrients overflow may dysregulate this function resulting in adipocytes hypertrophy, AT hypoxia, inflammation and oxidative stress. Other factors such as systemic inflammation and lifestyle behaviours may also contribute to the disruption of AT redox equilibrium and exacerbate obesity-associated oxidative stress. 
  • 1.1K
  • 18 Jun 2021
Topic Review
Trachodon Mummy
The Trachodon mummy is a fossilized natural mummy of Edmontosaurus annectens (originally known as Trachodon annectens), a duckbilled dinosaur. One of the finest dinosaur specimens so far discovered, it was the first including a skeleton encased in skin impressions from large parts of the body. This specimen has considerably influenced the scientific conception of duckbilled dinosaurs. Skin impressions found in between the fingers have been interpreted as evidence for an aquatic lifestyle; this hypothesis is now rejected. The mummy was found by fossil hunter Charles Hazelius Sternberg and his three sons near Lusk, Wyoming, United States in 1908. Although Sternberg was working under contract to the British Museum of Natural History, Henry Fairfield Osborn of the American Museum of Natural History managed to secure the mummy.
  • 1.1K
  • 27 Oct 2022
Biography
Faheem Hussain
Faheem Hussain (31 July 1942 – 29 September 2009), was a Pakistani theoretical physicist and a professor of physics at the Lahore University of Management Sciences (LUMS). A research scientist in the field of superstring theory at the National Center for Physics,[1] Hussain made contributions to the fields of superstring and string theory. He was the first Pakistani physicist to publish a rese
  • 1.1K
  • 27 Dec 2022
Topic Review
TPC1 in plants
TPC1 in plants is localized in the vacuolar membrane. Its activity is strictly regulated by several factors emphasizing its complex structure and function. The physiological role of TPC1 is under debate. The TPC1 hyperactive version fou2 (carring D454N mutation) is characterized by an overproduction of jasmonate acid (JA), however the tpc1-2 knockout mutant has no pronounced phenotype. The intriguing concept of Ca2+-induced Ca2+ release was assigned to Vicia faba TPC1 in 1994 by Ward and Schroeder, however it has still not been confirmed for the model plant Arabidopsis thaliana.
  • 1.1K
  • 27 Oct 2020
Topic Review
Biopesticide Global Market, Categories and Regulation
Biopesticides are formulations derived from naturally occurring compounds that manage pests through non-toxic and environmentally favorable means. Being living organisms (natural enemies) or products, biopesticides represent less of a risk to the environment and to human health. Biopesticides, classified into three broad classes, are increasingly used in pest control, and include semiochemicals, plant-incorporated protectants (PIPs), and compounds derived from plants and microorganisms.
  • 1.1K
  • 07 Mar 2023
Topic Review
Sustainable Exploitation of Posidonia oceanica Sea Balls (Egagropili)
Posidonia oceanica (L.) Delile is the main seagrass plant in the Mediterranean basin that forms huge underwater meadows. Its leaves, when decomposed, are transported to the coasts, where they create huge banquettes that protect the beaches from sea erosion. Its roots and rhizome fragments, instead, aggregate into fibrous sea balls, called egagropili, that are shaped and accumulated by the waves along the shoreline. Their presence on the beach is generally disliked by tourists, and, thus, local communities commonly treat them as waste to remove and discard. Posidonia oceanica egagropili might represent a vegetable lignocellulose biomass to be valorized as a renewable substrate to produce added value molecules in biotechnological processes, as bio-absorbents in environmental decontamination, to prepare new bioplastics and biocomposites, or as insulating and reinforcement materials for construction and building.
  • 1.1K
  • 23 Apr 2023
Topic Review
P(3HB-co-3HV)
Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (P(3HB-co-3HV)) is the most studied short-chain-length polyhydroxyalkanoates (PHA) with high application importance in various fields owing to its biodegradability, biocompatibility, renewability and thermoplastic properties. PHA are biopolyesters with plastic-like properties accumulated by microorganisms as a reserved energy source in the form of granules under carbon-excess and nitrogen-limited conditions. P(3HB-co-3HV) can be produced through microbial fermentation and has great potential as an alternative for non-biodegradable synthetic plastics.
  • 1.1K
  • 24 Feb 2022
Topic Review
Histone Acetyltransferase GCN5
Transcription of protein-encoding genes starts with forming a pre-initiation complex comprised of RNA polymerase II and several general transcription factors. To activate gene expression, transcription factors must overcome the repressive chromatin structure, which is accomplished with multiprotein complexes. Histone Acetyl Transferases (HAT) catalyze acetylation of specific lysine residues in histone N-tails, which are involved in transcriptional regulation and other nuclear processes. HATs are parts of large multiprotein complexes, like the SAGA complex, where their activity is enhanced, and their substrate specificity is altered. The whole complex is recruited to target sequences on the genome with other components involved in protein-protein interactions. A prototypical HAT which acts as a transcriptional adaptor is known as General Control Nonrepressed protein 5 (GCN5), first identified in Saccharomyces cerevisiae. GCN5 was defined biochemically as the first transcription-linked HAT with specificity for histone H3 lysine 14 (H3K14). However, GCN5 could also acetylate additional histone lysine residues, such as H3K9, H3K18, H3K23, H3K27, H3K36, other histones such as H4 and H2B and non-histone nuclear proteins.  In Arabidopsis, GCN5 is required for many developmental processes such as leaf development, apical dominance, root meristem activity, inflorescence, floral meristem function and flower fertility. 
  • 1.1K
  • 10 Feb 2021
Topic Review
Poly ADP-ribosylation in DNA Damage Response and Repair
Poly ADP-ribosylation (PARylation) is a post-translational modification process. Following the discovery of PARP-1, numerous studies have demonstrated the role of PARylation in the DNA damage and repair responses for cellular stress and DNA damage.
  • 1.1K
  • 08 Oct 2022
  • Page
  • of
  • 1815
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
ScholarVision Creations
Feedback