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All Topic Review Biography
Topic Review
Prevention and Treatment of Oral Complications
Phase I, before initiation of cancer treatment (review of medical record and oral history, planning of preventive strategies and dental treatments); phase II, from initiation of chemo-radiotherapy to 30–45 days post-therapy (maintenance of oral hygiene, reinforcement of parent/patient education in oral care, prevention and treatment of complications derived from cancer treatment); phase III, from 1 year to lifetime (periodic check-ups, maintenance, and reinforcement of oral hygiene, dental treatments, symptomatic care of the effects of long-term cancer treatment). The use of standardised protocols can avoid or minimise oral cancer complications and the side effects of cancer therapies. 
  • 373
  • 29 Apr 2022
Topic Review
Antifungals in Preventing Oropharyngeal Candidiasis among HIV-Infected Adults
Oropharyngeal candidiasis (OPC) is attributed to the overgrowth of the commensal fungi, Candida spp., in the mouth and throat. Among HIV-infected adults, there is an increased risk of developing OPC due to the loss of cell-mediated immunity. Fluconazole can be considered as an effective agent with a better safety profile for the prevention of OPC in HIV-infected adults.
  • 372
  • 22 Jun 2022
Topic Review
Matrix Metalloproteinases and Temporomandibular Joint Disorder
Temporomandibular disorders (TMD) are progressive degenerative disorders that affect the components of the temporomandibular joint (TMJ), characterized by pain and limitations in function. Matrix metalloproteinases (MMP) are enzymes involved in physiological breakdown of tissue that can have a pathological effect from an increase in activity during inflammation.
  • 374
  • 06 May 2023
Topic Review
Systemic Diseases and Biological Dental Implant Complications
The relationship between periodontitis and such systemic disorders as diabetes, cardiovascular disease and obesity has been extensively investigated. There is less scientific evidence available, however, regarding the influence of systemic diseases on the risk of late failure of dental implant rehabilitation due to peri-implantitis. Most of the literature concludes for no association between diabetes, cardiovascular disease, hypertension or osteoporosis and the risk of peri-implantitis. On the other hand, almost all the studies that investigated obesity as a risk factor for implant rehabilitation found a positive association between the two.
  • 369
  • 12 Jan 2023
Topic Review
Effects of Irrigating Solutions on Dentin
Irrigating solutions play an important role in the eradication of intracanal microbes and debris dissolution during endodontic treatment. Different combinations of solutions and protocols have been advocated, with sodium hypochlorite (NaOCl), ethylenediamine tetra acetic acid (EDTA), and chlorhexidine (CHX) remaining the most widely used ones by many clinicians. Although these solutions provide efficient inorganic dissolution and antimicrobial capacity, their use has also been reported to cause undesired effects on root dentin composition and mechanical and biomechanical properties, such as microhardness, surface roughness, bond strength, and matrix metalloproteinase (MMP) activity.
  • 369
  • 19 Dec 2022
Topic Review
Desquamative Gingivitis
Desquamative gingivitis is a clinical condition with a chronic course, not specific to a particular disease, characterized by intense erythema, scaling, vesicles, and/or blisters that may involve both the marginal free gingiva (MG) and the neighboring adherent gingiva (AG). 
  • 367
  • 07 Oct 2023
Topic Review
Artificial Intelligence-Assisted Discrimination of Oral Cancerous Lesions
Early detection of oral cancer is important to increase the survival rate and reduce morbidity. For the past few years, the early detection of oral cancer using artificial intelligence (AI) technology based on autofluorescence imaging, photographic imaging, and optical coherence tomography imaging has been an important research area. 
  • 365
  • 01 Aug 2022
Topic Review
Non-Coding RNA Transcriptome
Non-coding RNAs (ncRNAs) represent a research hotspot by playing a key role in epigenetic and transcriptional regulation of diverse biological functions. Due to their involvement in DNA translational control, their regulation of mRNA and protein expression levels and their ability to reprogram cellular signaling pathways in oral inflammatory diseases, ncRNA could be used to diagnose and predict disease and to improve patient-tailored treatments, as integral part of precision medicine for oral inflammatory diseases. 
  • 359
  • 09 Aug 2022
Topic Review
CAD/CAM Denture Base Materials
The data about bond strength between digitally produced denture base resins and artificial teeth are scarce. No statistical differences between heat-polymerized and CAD/CAM (milled) denture base materials when attached with different types of artificial teeth, while one study showed higher values of CAD/CAM (milled) denture base materials. Bonding agents ensure bonding strength at least similar to the conventional methods. In order to improve the quality of future studies, it would be advantageous to use a larger number of specimens with standardized dimensions and a blinded testing machine operator to decrease the risk of bias.
  • 359
  • 23 Mar 2023
Topic Review
Diet, Nutrition, and Oral Health in Older Adults
Diet, nutrition, and oral health are closely linked. Malnutrition is a challenging health concern in older adults that is associated with physical decline affecting their daily activities and quality of life.
  • 354
  • 07 Oct 2023
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