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Topic Review
SLC25A24 Gene
solute carrier family 25 member 24
  • 770
  • 24 Dec 2020
Topic Review
Erythrokeratodermia Variabilis et Progressiva
Erythrokeratodermia variabilis et progressiva (EKVP) is a skin disorder that is present at birth or becomes apparent in infancy. Although its signs and symptoms vary, the condition is characterized by two major features.
  • 770
  • 25 Dec 2020
Topic Review
MYOC Gene
myocilin
  • 769
  • 23 Dec 2020
Topic Review
Isolated HyperCKemia
Isolated hyperCKemia is a condition characterized by elevated levels of an enzyme called creatine kinase in the blood.
  • 769
  • 23 Dec 2020
Topic Review
SUMF1 Gene
Sulfatase modifying factor 1: The SUMF1 gene provides instructions for making an enzyme called formylglycine-generating enzyme (FGE). 
  • 769
  • 24 Dec 2020
Topic Review
ASPM Gene
abnormal spindle microtubule assembly
  • 769
  • 24 Dec 2020
Topic Review
Paget Disease of Bone
Paget disease of bone is a disorder that causes bones to grow larger and weaker than normal. Affected bones may be misshapen and easily broken (fractured).
  • 769
  • 24 Dec 2020
Topic Review
Maturity-Onset Diabetes of the Young
Maturity-onset diabetes of the young (MODY) is a group of several conditions characterized by abnormally high blood sugar levels. These forms of diabetes typically begin before age 30, although they can occur later in life. In MODY, elevated blood sugar arises from reduced production of insulin, which is a hormone produced in the pancreas that helps regulate blood sugar levels. Specifically, insulin controls how much glucose (a type of sugar) is passed from the blood into cells, where it is used as an energy source.
  • 768
  • 23 Dec 2020
Topic Review
DKC1 Gene
Dyskerin Pseudouridine Synthase 1: The DKC1 gene provides instructions for making a protein called dyskerin. 
  • 768
  • 24 Dec 2020
Topic Review
NOTCH1 Gene
notch 1
  • 768
  • 24 Dec 2020
Topic Review
ADAMTSL4 Gene
ADAMTS like 4
  • 768
  • 05 Apr 2021
Topic Review
TPP1 Gene
Tripeptidyl peptidase 1: The TPP1 gene provides instructions for making an enzyme called tripeptidyl peptidase 1.
  • 768
  • 25 Dec 2020
Topic Review
SAA1 Gene
serum amyloid A1
  • 768
  • 24 Dec 2020
Topic Review
ATL1 Gene
atlastin GTPase 1. The ATL1 gene provides instructions for producing a protein called atlastin-1. 
  • 767
  • 24 Dec 2020
Topic Review
EMD Gene
Emerin: The EMD gene provides instructions for making a protein called emerin. 
  • 767
  • 24 Dec 2020
Topic Review
NR0B1 Gene
nuclear receptor subfamily 0 group B member 1
  • 767
  • 24 Dec 2020
Topic Review
ORC4 Gene
origin recognition complex subunit 4
  • 767
  • 24 Dec 2020
Topic Review
Epigenetic/non-epigenetic mechanisms of HIV control
The persistence of latent HIV provirus pools in different resting CD4+ cell subsets remains the greatest obstacle in the current efforts to treat and cure HIV infection. Recent efforts to purge out latently infected memory CD4+ T-cells using latency-reversing agents have failed in clinical trials. This review discusses the epigenetic and non-epigenetic mechanisms of HIV latency control, major limitations of the current approaches of using latency-reversing agents to reactivate HIV latency in resting CD4+ T-cells, and potential solutions to these limitations.
  • 767
  • 16 Apr 2021
Topic Review
GRN Gene
Granulin precursor
  • 766
  • 22 Dec 2020
Topic Review
GM1 Gangliosidosis
GM1 gangliosidosis is an inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord.
  • 766
  • 23 Dec 2020
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