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Topic Review
Higher Blood Pressure & Neurodegeneration
High Blood Pressure (Hypertension) is a major risk factor for cerebral health. Midlife hypertension is associated with a two- to five-fold increased risk of stroke, and up to 50% greater risk of developing vascular dementia. Moreover, hypertension is also linked to the development of amyloid angiopathy, the progression of white matter lesions (WMLs), and neurodegeneration. This recent meta-analysis demonstrates that higher blood pressure, even within the normal range, is associated with a reduction in global and regional brain volumes.
  • 601
  • 06 Mar 2021
Topic Review
Non-Invasive Prenatal Testing
New technologies such as non-invasive prenatal testing (NIPT), capable of analyzing cell-free fetal DNA in the maternal bloodstream, have become increasingly widespread and available, which has in turn led to ethical and policy challenges that need addressing. NIPT is not yet a diagnostic tool, but can still provide information about fetal genetic characteristics (including sex) very early in pregnancy, and there is no denying that it offers valuable opportunities for pregnant women, particularly those at high risk of having a child with severe genetic disorders or seeking an alternative to invasive prenatal testing. Nonetheless, the ethical, legal and social implications (ELSI) include multiple aspects of informed decision-making, which can entail risks for the individual right to procreative autonomy, in addition to the potential threats posed by sex-selective termination of pregnancy (in light of the information about fetal sex within the first trimester), and the stigmatization and discrimination of disabled individuals. 
  • 599
  • 10 Feb 2021
Topic Review
Mitochondrial and Sperm Physiology
Besides ATP production, mitochondria are key organelles in several cellular functions, such as steroid hormone biosynthesis, calcium homoeostasis, intrinsic apoptotic pathway, and the generation of reactive oxygen species (ROS). Despite the loss of the majority of the cytoplasm occurring during spermiogenesis, mammalian sperm preserves a number of mitochondria that rearrange in a tubular structure at the level of the sperm flagellum midpiece. Although sperm mitochondria are destroyed inside the zygote, the integrity and the functionality of these organelles seem to be critical for fertilization and embryo development. 
  • 598
  • 01 Feb 2021
Topic Review
Sodium Intake and Heart Failure
Sodium is an essential mineral and nutrient used in dietary practices across the world and is important to maintain proper blood volume and blood pressure. A high sodium diet is associated with increased expression of β—myosin heavy chain, decreased expression of α/β—myosin heavy chain, increased myocyte enhancer factor 2/nuclear factor of activated T cell transcriptional activity, and increased salt-inducible kinase 1 expression, which leads to alteration in myocardial mechanical performance. A high sodium diet is also associated with alterations in various proteins responsible for calcium homeostasis and myocardial contractility. Excessive sodium intake is associated with the development of a variety of comorbidities including hypertension, chronic kidney disease, stroke, and cardiovascular diseases.
  • 596
  • 22 Dec 2020
Topic Review
Transition Care in Rheumatology
The transition from pediatric to adult health care is a challenging yet important process in rheumatology as most childhood-onset rheumatic diseases persist into adulthood. Numerous reports on unmet needs as well as evidence of negative impact from poor transition have led to increased efforts to improve transition care, including international guidelines and recommendations. In line with these recommendations, transition programs along with transition readiness assessment tools have been established. This entry focuses on how transition care in rheumatology has developed in recent years and highlights the gaps in current practices.
  • 588
  • 02 Mar 2021
Topic Review
Self-Management of Chronic Disease in Children
Self-management of chronic illness leads to improved health outcomes. The acquisition of self-management skills in pediatrics is a process supported by the family, health professionals and the community, in which the nurse, in partnership, can promote communication and health education through cognitive strategies, behavioral programs included in physical or online programs, adjusted to the patients’ needs.
  • 587
  • 18 Jan 2022
Topic Review
Parenting Programme
Parenting programmes are important ways to contribute to a healthy, sustainable, and resilient society. They benefit parents by reducing signs of stress and depression and increasing their self-efficacy and social behaviour, which leads to positive changes in childcare. In addition, they bring benefits to the parent–child relationship by relieving social pressure from parents, allowing a focus on the relationship with the child as an individual. Parenting programmes also positively affect society through knowledge sharing, networking, and support so that children can grow up in healthy environments and maximise their full potential.
  • 585
  • 25 Oct 2022
Topic Review
Hippotherapy, Children and Cerebral Palsy
Cerebral palsy is described as a group of permanent neuromotor-type disorders caused by non-progressive injuries in the developmental stages of the central nervous system, and which have serious repercussions on the quality of life of affected children due to the physical and psychological damage it entails for them. Today, it is the leading cause of physical disability in childhood. Since there is no cure for this disorder, treatment is based on the improvement of symptoms, which is not always achieved through conventional therapies. For this reason, the need arises to investigate other alternative therapies, such as hippotherapy, to determine the main effects of hippotherapy as a rehabilitation therapy in children with cerebral palsy. As a conclusion, we found that hippotherapy provides benefits at physical, psychological, cognitive and social levels in children with cerebral palsy, and thus it should be considered as a complementary rehabilitation therapy to conventional treatments.
  • 584
  • 23 Jun 2021
Topic Review
Organic Fresh Produce
Growing and purchasing demand for organic fresh produce is increasing rapidly. Consumers are aware of health, environmental safety, pesticide harmfulness, nutrients, bioactive compounds, and safe food. Many research works are available on organic and conventional fresh produce. As organic fresh produce growing and purchasing demand is increasing, it has become necessary to review the recent trends in quality, safety, and consumer preferences of organic and conventional fresh food products. A few reports have been compiled on organic and conventional fresh produce. Researchers have started working on organic and conventional fresh produce with the help of modern technology to improve nutritional and functional quality, safety, and consumer preferences. Nutritional and functional quality, safety, and consumer preferences depend on cultivation techniques, treatment, crop cultivar, and appearance of products. Therefore, it is necessary to compile the literature on organic and conventional fresh produce based on quality, safety, and consumer preferences.
  • 581
  • 07 May 2021
Topic Review
COVID-19: Short and Long-Term Effects
The COVID-19 pandemic has recently been the cause of a global public health emergency. Frequently, elderly patients experience a marked loss of muscle mass and strength during hospitalization, resulting in a significant functional decline.
  • 558
  • 23 Jan 2021
Topic Review
Food of Pre-Hispanic Inhabitants from the Quito Plateau
In all of the different historical periods during its development, the pre-Hispanic inhabitants of the Quito plateau and its valleys used the flora and fauna for food and the development of their society. 
  • 558
  • 06 Dec 2022
Topic Review
Clinical Exercise Physiologists
Clinical exercise physiologists (CEPs) specialize in managing long-term, non-communicable health conditions using scientific rehabilitative exercise prescription, which alleviates the burden of these conditions on health care systems. This is evident, particularly in Australia (AUS), where they are registered as health care workers. CEPs have been shown to reduce the physical burden of long-term conditions on populations and the economic load that these place on national health departments.
  • 557
  • 22 Feb 2021
Topic Review
Epidemiology of Hepatitis E Virus
The hepatitis E virus (HEV) is a positive single-stranded, icosahedral, quasi-enveloped RNA virus in the genus Orthohepevirus of the family Hepeviridae. Orthohepevirus A is the most numerous species of the genus Orthohepevirus and consists of eight different HEV genotypes that can cause infection in humans. HEV is a pathogen transmitted via the fecal–oral route, most commonly by consuming fecally contaminated water. A particular danger is the HEV-1 genotype, which poses a very high risk of vertical transmission from the mother to the fetus.
  • 550
  • 23 Apr 2021
Topic Review
Meta-Analysis of Flipped Learning Effects in Nursing Education
This is a meta-analysis of the effect of the outcome variables of fragment learning in nursing education, such as clinical strength, critical thinking ability, self dominance and learning satisfaction.
  • 516
  • 20 Dec 2021
Topic Review
Physical Therapy intervene Critically-Ill COVID-19
As part of COVID-19 consequences, it has been estimated that 5% of patients affected by this dis-ease will require admission to the intensive care unit (ICU), and physical therapy techniques have been implemented in patients with other conditions admitted to ICU.
  • 510
  • 02 Mar 2021
Topic Review
Hospital Ethical Climate and Job Satisfaction among Nurses
Ethical climate can be defined as a set of behaviors, emotions and impressions characteristic for a given organization and shaped by a number of factors, such as professional values, norms, views, and cultivated tradition. The concept of the Ethical Climate Theory (ECT) dates back to the 1980s. The ECT authors, B. Victor and J.B. Cullen, classified the following five types of climate: caring, independent, rules, rights referred to as professional, and instrumental.
  • 503
  • 21 Apr 2022
Topic Review
Nurses’ Job Satisfaction in Saudi Arabian Hospitals
Job satisfaction can be defined as the extent to which people feel either positively or negatively about their work. Job satisfaction can also be defined as the degree to which an employee is satisfied with the benefits they receive from their work, especially when it comes to intrinsic motivations. It is a complicated concept that has been studied in many different fields, such as nursing, business, psychological science, and sociology. 
  • 494
  • 19 Oct 2023
Topic Review
Geriatric Care Management System Powered by the IoT
The digitalisation of geriatric care refers to the use of emerging technologies to manage and provide person-centered care to the elderly by collecting patients’ data electronically and using them to streamline the care process, which improves the overall quality, accuracy, and efficiency of healthcare. In many countries, healthcare providers still rely on the manual measurement of bioparameters, inconsistent monitoring, and paper-based care plans to manage and deliver care to elderly patients. This can lead to a number of problems, including incomplete and inaccurate record-keeping, errors, and delays in identifying and resolving health problems. 
  • 487
  • 20 Jul 2023
Topic Review
Analyzing Heart Failure Care by Actor-Partner Interdependence Model
Heart failure (HF) is a complex, heterogeneous, increasingly prevalent cardiovascular disorder with high morbidity and mortality. Self-care behaviors are essential for the effective treatment of heart failure, and poor self-care may lead to adverse clinical events in patients with HF, including repeated hospitalizations, poor quality of life, and increased mortality. One of the most common approaches for analyzing data on HF self-care dyads is the Actor–Partner Interdependence Model (APIM). Studies using the APIM approach revealed interrelated patient and caregiver characteristics that influence self-care and explain many complex dyadic behaviors. 
  • 482
  • 15 Apr 2022
Topic Review
Monitoring healthcare professionals with SUD
In the past decades, monitoring programs have been developed for healthcare professionals with substance use disorders. We aimed to explore estimates of abstinence and work retention rates after participation in such monitoring programs. 
  • 477
  • 31 Jan 2021
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