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Topic Review
Child Marriage in South Asia
Child marriage is a serious public health issue with dire implications at the individual and societal level. Child marriage refers to formal marriages and informal unions in which one or both parties are under 18 years of age and live with a partner as if married. Almost half of all child marriages globally originate from South Asia. 
  • 1.4K
  • 30 Nov 2022
Topic Review
Dementia
Dementia is a syndrome that is characterised by the decline of different cognitive abilities. A high rate of deaths and high cost for detection, treatments, and patients care count amongst its consequences. Although there is no cure for dementia, a timely diagnosis helps in obtaining necessary support, appropriate medication, and maintenance, as far as possible, of engagement in intellectual, social, and physical activities. The early detection of Alzheimer Disease (AD) is considered to be of high importance for improving the quality of life of patients and their families. In particular, Virtual Reality (VR) is an expanding tool that can be used in order to assess cognitive abilities while navigating through a Virtual Environment (VE).
  • 1.4K
  • 05 Feb 2021
Topic Review
Mechanism of Bone Loss Induced by Iron Deficiency
Iron is a vital component of various enzymes involved in many biological processes, including oxygen transport, DNA biosynthesis, and cellular energy generation. Moreover, the biological activity of iron depends mainly on its efficient electron transfer properties. It has the ability to accept or donate electrons during the conversion between ferric iron (Fe3+) and ferrous iron (Fe2+), thereby functioning as a catalytic cofactor in various biochemical reactions. Therefore, iron is necessary for the growth, proliferation, and differentiation of bone cells, especially for osteoblasts and osteoclasts. In addition, hypoxia caused by iron deficiency can also lead to the activity and function disorder of bone cells. With respect to bone metabolism, iron is involved in the synthetic process of collagen and vitamin D metabolism.
  • 1.4K
  • 12 Apr 2023
Topic Review
Skeletal Fluorosis
Fluorine is widely dispersed in nature and has multiple physiological functions. Although it is usually regarded as an essential trace element for humans, this view is not held universally. Moreover, chronic fluorosis, mainly characterized by skeletal fluorosis, can be induced by long-term excessive fluoride consumption. High concentrations of fluoride in the environment and drinking water are major causes, and patients with skeletal fluorosis mainly present with symptoms of osteosclerosis, osteochondrosis, osteoporosis, and degenerative changes in joint cartilage. Etiologies for skeletal fluorosis have been established, but the specific pathogenesis is inconclusive. Currently, active osteogenesis and accelerated bone turnover are considered critical processes in the progression of skeletal fluorosis. In recent years, researchers have conducted extensive studies in fields of signaling pathways (Wnt/β-catenin, Notch, PI3K/Akt/mTOR, Hedgehog, parathyroid hone, and insulin signaling pathways), stress pathways (oxidative stress and endoplasmic reticulum stress pathways), epigenetics (DNA methylation and non-coding RNAs), and their inter-regulation involved in the pathogenesis of skeletal fluorosis.
  • 1.4K
  • 11 Nov 2021
Topic Review
Current Market for Functional Foods and Consumption Intention
Functional foods generally refer to foods with one or more particular functions and positive effects on human health, often in relation to nutrition or reducing disease risk. The growth of the functional food market has been largely caused by concerns about rising medical and healthcare costs, the desire to improve the quality of later life with the steady increase in life expectancy, and scientific evidence that functional foods are beneficial to health. Purchase intention, which is strongly associated with market expansion, is the likelihood that consumers plan to purchase specific products or services. Consumer attitude towards a certain product or brand, along with certain external factors, promote consumers’ purchase intentions and are crucial indicators for predicting consumer behaviour.
  • 1.4K
  • 15 Jul 2022
Topic Review
Lonomia obliqua Envenoming
The hemorrhagic syndrome is one of the most serious complications in patients who have  been in contact with the Lonomia caterpillar bristles. Although 26 species of the genus Lonomia (Saturniidae family) are distributed in the American continent, the most studied species are L. obliqua and L. achelous caterpillars; both are capable of inducing hemorrhagic effects in humans. Envenoming by L. obliqua caterpillars was considered a public health problem in southern Brazil. The hemostatic disturbances observed in the envenoming by L. obliqua caterpillars, result in a consumption coagulopathy, resembling a disseminated intravascular coagulation (DIC) and secondary fibrinolysis, which can lead to the hemorrhagic syndrome. The main complication of L. obliqua envenomation is acute renal failure, which can occur in up to 12% of the cases, being frequent in patients over 45 years old and in those with heavy bleeding. Besides that, some deaths related to hemorrhage and renal failure have been reported. However, the early diagnosis and proper treatment with  antilonomic serum (ALS), produced by the Butantan Institute (SP/Brazil), within 12 h of contact can prevent severe coagulopathy and hemorrhage events. 
  • 1.4K
  • 22 Dec 2021
Topic Review
Polyethylene Terephthalate Recycling Techniques
Polyethylene terephthalate (PET) is a widely used thermoplastic with excellent properties, making it a popular choice for various packaging and single-use plastic products. Its exceptional tensile strength, processability, transparency, thermal stability, barrier properties, toughness-to-weight ratio, and chemical resistance have contributed to its widespread use. However, the significant consumption of PET has led to a substantial amount of PET waste, especially in the form of single-use packaging. This has raised concerns about the environmental impact of plastic waste, such as marine pollution and landfill accumulation.
  • 1.4K
  • 14 Aug 2023
Topic Review
Mental Health of Self-Employed
We included 26 (three longitudinal and 23 cross-sectional) population-based studies of good quality, with data from 3,128,877 participants in total. A Swedish national register evaluation with 25 years follow-up, showed a higher incidence of mental illness among the self-employed compared to white-collar workers, but a lower incidence compared to blue-collar workers. In the second longitudinal study from Sweden the self-employed had a lower incidence of mental illness compared to both blue- and white-collar workers over 15 years, whereas the third longitudinal study (South Korea) did not find a difference regarding the incidence of depressive symptoms over 6 years. A higher prevalence of mental disorders among the self-employed compared to employees was true for the Asian and older European cross-sectional studies. However, most of the European cross-sectional studies from the last decade found lower or similar prevalence estimates among the self-employed. The majority of the American and Australian cross-sectional studies found a similar prevalence of mental disorders among the self-employed and the employees.
  • 1.4K
  • 28 Sep 2021
Topic Review
Type-I IFN Signaling
The interferon (IFN) family of cytokines is broadly classified into type I, II, and III. The IFN-I consists of 13 subtypes, including IFNα, β, κ, ε, ω, and τ, all of which bind to the interferon-alpha receptor complex (IFNAR), composed of the IFNARI and IFNARII chains.
  • 1.4K
  • 04 Jun 2021
Topic Review
Streptococcus pyogenes
Streptococcus pyogenes, (colloquially named “group A streptococcus” (GAS)), is a Gram-positive bacterial pathogen that can cause both non-invasive and invasive disease (iGAS), as well as nonsuppurative sequelae. This includes pharyngitis, scarlet fever, impetigo, cellulitis, type II necrotizing fasciitis, streptococcal toxic shock syndrome, acute rheumatic fever and post-streptococcal glomerulonephritis.
  • 1.4K
  • 16 May 2021
Topic Review
Industrial Animal Farming and COVID-19
The threat of zoonoses (i.e., human infectious diseases transmitted from animals) because of industrial animal farming may be receiving less attention in society due to the putative wildlife origin of COVID-19. To identify societal responses to COVID-19 that do address or affect the risk of future zoonoses associated with industrial animal farming, the literature was screened for measures, actions, proposals and attitudes following the guidelines of a scoping review. Forty-one articles with relevant information published between 1 January 2020 and 30 April 2021 were identified directly or indirectly via bibliographies from 138 records retrieved via Google Scholar. Analysis of relevant content revealed ten fields of policy action amongst which biosecurity and change in dietary habits were the dominant topics. Further search for more relevant records within each field of policy action retrieved another 8 articles. Identified responses were furthermore classified and evaluated according to groups of societal actors, implying different modes of regulation and governance. Based on the results, a suggested policy strategy is presented for moving away from food production in factory farms and supporting sustainable farming, involving the introduction of a tax on the demand side and subsidies for the development and production of alternative meat.
  • 1.4K
  • 31 Aug 2021
Topic Review
COVID-19 Impact on Yellow/Lassa Fever Infections in Nigeria
Lassa fever (LF) and yellow fever (YF) belong to a group of viral hemorrhagic fevers (VHFs). These viruses have common features and damages the organs and blood vessels; they also impair the body’s homeostasis. Some VHFs cause mild disease, while some cause severe disease and death such as in the case of Ebola or Marburg. LF virus and YF virus are two of the emerging viruses in Africa, resulting in severe hemorrhagic fever in humans. Lassa fever virus is continuously on the rise both in Nigeria and neighboring countries in West Africa, with an estimate of over 500,000 cases of LF, and 5000 deaths, annually. YF virus is endemic in temperate climate regions of Africa, Central America (Guatemala, Honduras, Nicaragua, El Salvador), and South America (such as Brazil, Argentina, Peru, and Chile) with an annual estimated cases of 200,000 and 30,000 deaths globally. 
  • 1.4K
  • 02 Dec 2022
Topic Review
Landscape Preference
Landscape preference (LP) is often a critical interdisciplinary research topic that explores the interaction between human beings and their environments. Human preferences for landscape can have a profound influence on how the preservation, reconstruction, and restoration of the landscape is approached, both consciously and unconsciously. Theories of LP emerged in the 1960s and can be divided into three need categories: (1) the need for survival, (2) the need for affection, and (3) the need for cognition.
  • 1.3K
  • 28 Jun 2023
Topic Review
Air Pollution Affects Placental DNA Methylation
The Developmental Origins of Health and Disease (DOHaD) concept postulates that in utero exposures influence fetal programming and health in later life. Throughout pregnancy, the placenta plays a central role in fetal programming; it regulates the in utero environment and acts as a gatekeeper for nutrient and waste exchange between the mother and the fetus. Maternal exposure to air pollution, including heavy metals, can reach the placenta, where they alter DNA methylation patterns, leading to changes in placental function and fetal reprogramming. In this entry, we explore the current knowledge on placental DNA methylation changes associated with prenatal air pollution (including heavy metals) exposure and highlight its effects on fetal development and disease susceptibility.
  • 1.3K
  • 15 Nov 2021
Topic Review
Impact of Lockdown on PM Charecterisitcs
Air is a diverse mixture of gaseous and suspended solid particles. Several new substances are being added to the air daily, polluting it and causing human health effects. Particulate matter (PM) is the primary health concern among these air toxins. The World Health Organization (WHO) addressed the fact that particulate pollution affects human health more severely than other air pollutants. The spread of air pollution and viruses, two of the millennium’s most serious concerns, have been linked closely. 
  • 1.3K
  • 26 Oct 2022
Topic Review
Biochar in Soil Systems Regulation
Biochar is a carbon-rich material prepared from the pyrolysis of biomass under various conditions. Recently, biochar drew great attention due to its promising potential in climate change mitigation, soil amendment, and environmental control. Obviously, biochar can be a beneficial soil amendment in several ways including preventing nutrients loss due to leaching, increasing N and P mineralization, and enabling the microbial mediation of N2O and CO2 emissions.
  • 1.3K
  • 25 Jun 2021
Topic Review
Managing Earthquake Debris
Earthquakes have the potential to cause severe and widespread structural damage to buildings and infrastructure in the affected area. Earthquake debris mainly results from building collapses during intense ground motion and the emergency demolition of damaged and unstable buildings following a devastating earthquake. Debris management constitutes a major challenge that must be met by all those participating in disaster management as it poses threats to both the natural environment and public health in an earthquake-affected area. 
  • 1.3K
  • 13 Nov 2023
Topic Review
Genetically Modified Food
The concept of “genetically modified organisms” (GMOs) refers to those organisms whose genome has been altered by inserting a gene from another organism, removing a gene, or changing a gene’s function to generate a desirable trait.
  • 1.3K
  • 25 Mar 2022
Topic Review
Role of 10-Hydroxy-2-decenoic Acid in Alzheimer’s Disease
Alzheimer’s disease (AD) represents a significant public health concern in modern society. Metabolic syndrome (MetS), which includes diabetes mellitus (DM) and obesity, represents a modifiable risk factor for AD. MetS and AD are interconnected through various mechanisms, such as mitochondrial dysfunction, oxidative stress, insulin resistance (IR), vascular impairment, inflammation, and endoplasmic reticulum (ER) stress. Therefore, it is necessary to seek a multi-targeted and safer approach to intervention. Thus, 10-hydroxy-2-decenoic acid (10-HDA), a unique hydroxy fatty acid in royal jelly, has shown promising anti-neuroinflammatory, blood–brain barrier (BBB)-preserving, and neurogenesis-promoting properties.
  • 1.3K
  • 01 Sep 2023
Topic Review
Reasons for Withdrawal of Microplastics from Abrasive Cosmetics
Microplastics have been widely used in cosmetics and, among other things, very often as an abrasive component in peelings. This type of additive is not the main cause of environmental microplastic contamination, but it can pose a significant threat to the environment and to people. Manufacturers are increasingly taking the decision to withdraw microplastics from cosmetics, replacing them with alternatives, and this is also happening because of legal requirements. 
  • 1.3K
  • 17 Nov 2023
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