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Topic Review
Wave Race 64
Wave Race 64 is a racing video game developed by Nintendo EAD and published by Nintendo. It was released for the Nintendo 64 in 1996 and is a follow-up to the 1992 Game Boy title Wave Race. Most of the game involves the player racing on a Jet Ski on a variety of courses while successfully manoeuvring the vehicle around various buoys. A multiplayer mode where two players can compete against each other on a chosen course is also included. The game supports the Controller Pak, which allows players to transfer saved data from one game cartridge to another. Originally referred to as "F-Zero on water", the game was intended to feature high-speed boats with transforming capabilities, but these were ultimately replaced with Jet Skis as producer Shigeru Miyamoto felt that the game would not be differentiated enough from other titles on other systems. Wave Race 64 received acclaim from critics, who praised the game's satisfying controls and dynamic watery environments. The game is credited for helping Nintendo effectively make its paradigmatic leap from the 16-bit 2D graphics of the Super Nintendo Entertainment System to the Nintendo 64's 3D capabilities. It was re-released for the Wii and Wii U's Virtual Console in 2007 and 2016, respectively. A sequel, Wave Race, was released in 2001.
  • 2.2K
  • 13 Oct 2022
Topic Review
Water Scarcity
Water scarcity, defined as long-term water imbalances occurring when the level of water demand exceeds natural water availability and supply capacity, is expected to pose high risks to both societies and economies in the next decade.
  • 2.2K
  • 03 Feb 2022
Topic Review
Hydrogen Peroxide
Hydrogen peroxide (H2O2) is an important oxidation molecule regulating aerobic metabolism. Redox signals include physiological oxidative stress (EU stress), and excessive oxidative stress can damage molecules. The main enzyme sources of H2O2 are nicotinamide adenine dinucleotide phosphate oxidase or NADPH oxidase (NOx), mitochondrial respiratory chain and various kinds of oxidase. NOx family consists of seven enzyme subtypes, which produce a superoxide anion (O2 -) which can be converted to H2O2 by superoxide dismutase or spontaneously. H2O2 passes through the membrane through some aquaporin (AQP), which is called porphyrin hydroperoxide. It diffuses in cells and tissues, triggering cellular effects such as proliferation, immune cell recruitment and morphological changes. 
  • 2.2K
  • 27 Jan 2022
Topic Review
AWS Architecture for Smart Livestock
In the ecological future of the planet, intelligent agriculture relies on CPS and IoT to free up human resources and increase production efficiency. Due to the growing number of connected IoT devices, the maximum scalability capacity, and available computing power of the existing architectural frameworks will be reached. This necessitates finding a solution that meets the continuously growing demands in smart farming. Cloud-based IoT solutions are achieving increasingly high popularity. The aim of this study was to design a scalable cloud-based architecture for a smart livestock monitoring system following Agile methodology and featuring environmental monitoring, health, growth, behaviour, reproduction, emotional state, and stress levels of animals. The AWS services used, and their specific tasks related to the proposed architecture are explained in detail. A stress test was performed to prove the data ingesting and processing capability of the proposed architecture. Experimental results proved that the proposed architecture using AWS automated scaling mechanisms and IoT devices are fully capable of processing the growing amount of data, which in turn allow for meeting the required needs of the constantly expanding number of CPS systems. 
  • 2.2K
  • 17 Sep 2021
Topic Review
Desert Island Discs
Desert Island Discs is a radio programme broadcast on BBC Radio 4. It was first broadcast on the BBC Forces Programme on 29 January 1942. Each week a guest, called a 'castaway' during the programme, is asked to choose eight recordings (usually, but not always, music), a book and a luxury item that they would take if they were to be cast away on a desert island, whilst discussing their lives and the reasons for their choices. It was devised and originally presented by Roy Plomley. Since 2006, the programme has been presented by Kirsty Young. More than 3,000 episodes have been recorded, with some guests having appeared more than once and some episodes featuring more than one guest. An example of a guest who falls into both categories is Bob Monkhouse, who appeared with his co-writer Denis Goodwin on 12 December 1955 and in his own right on 20 December 1998.
  • 2.2K
  • 01 Nov 2022
Topic Review
Microbial PolyHydroxyAlkanoate Biopolymers
PolyHydroxyAlkanoates (PHAs) fulfil every criterion set out in the definition of a natural polymer or a biopolymer. PHA biopolymers, a group of biopolyesters, are found in nature, and they are biosynthesized using renewable carbon in microbes. PHAs are biodegradable, because nature has the tools to convert them into CO2 and water and about 10% organic fertilizer or humus, the same as in the biodegradation of cellulose or cotton.
  • 2.2K
  • 07 Aug 2023
Topic Review
Curing
Curing is a chemical process employed in polymer chemistry and process engineering that produces the toughening or hardening of a polymer material by cross-linking of polymer chains. Even if it is strongly associated with the production of thermosetting polymers, the term "curing" can be used for all the processes where a solid product is obtained from a liquid solution, such as will PVC plastisols.
  • 2.2K
  • 26 Oct 2022
Topic Review
Hydrogen Adsorption in Metal–Organic Frameworks
The development of hydrogen technologies and a wider use of hydrogen fuel cell systems require new materials that can store large amounts of hydrogen at relatively low pressures with small volume, low weight, and fast kinetics for recharging. Among the most challenging materials for hydrogen storage are porous coordination polymers, also called metal–organic frameworks (MOFs). MOFs are two- or three-dimensional porous crystalline materials with infinite lattices. As a result of their ultra-high surface area values (more than 2500 m2·g–1 measured by the Brunauer–Emmett–Teller (BET) approach), they were found to be promising gas adsorbers for small gaseous molecules, including CH4, CHCl3, CCl4, C6H6, C6H12, CO2, Ar, N2, and H2. The main benefit of MOFs is their reversible and high-rate hydrogen adsorption process. A reasonable number of H2 molecules inside the body of MOFs may only be obtained at very low temperatures. To date, MOFs have shown significant progress in applications of gas separation, catalysis, and coordination chemistry.
  • 2.2K
  • 09 Aug 2021
Topic Review
Fog and IoT Driven Healthcare
Technological advancements have made it possible to monitor, diagnose, and treat patients remotely. The vital signs of patients can now be collected with the help of Internet of Things (IoT)-based wearable sensor devices and then uploaded on to a fog server for processing and access by physicians for recommending prescriptions and treating patients through the Internet of Medical Things (IoMT) devices. 
  • 2.2K
  • 07 Sep 2022
Topic Review
Structure of Humic Substances
Humic substances (HS) are dominant components of soil organic matter and are recognized as natural, effective growth promoters to be used in sustainable agriculture. In recent years, many efforts have been made to get insights on the relationship between HS chemical structure and their biological activity in plants using combinatory approaches. Relevant results highlight the existence of key functional groups in HS that might trigger positive local and systemic physiological responses via a complex network of hormone-like signaling pathways. The biological activity of HS finely relies on their dosage, origin, molecular size, degree of hydrophobicity and aromaticity, and spatial distribution of hydrophilic and hydrophobic domains. The molecular size of HS also impacts their mode of action in plants, as low molecular size HS can enter the root cells and directly elicit intracellular signals, while high molecular size HS bind to external cell receptors to induce molecular responses. Main targets of HS in plants are nutrient transporters, plasma membrane H+-ATPases, hormone routes, genes/enzymes involved in nitrogen assimilation, cell division, and development. 
  • 2.2K
  • 08 May 2021
Topic Review
M-16V as Infant Probiotic
Bifidobacterium breve M-16V is a commonly used probiotic strain in infants. M-16V has been demonstrated to offer potential in protecting infants from developing devastating necrotising enterocolitis (NEC) and allergic diseases.
  • 2.2K
  • 10 Sep 2021
Topic Review
Green Innovation Performance
Green innovation performance refers to enterprise’s improvement of their product design or production process in terms of environmental protection and environmental management. Green innovation performance includes green product innovation performance and green process innovation performance from the perspective of innovation objects.
  • 2.2K
  • 06 Apr 2022
Topic Review
Building Design for Preventing COVID-19 Pandemic
Sustainable design methods aim to obtain architectural solutions that assure the coexistence and welfare of human beings, inorganic structures, and living things that constitute ecosystems. The novel coronavirus emergence, inadequate vaccines against the present severe acute respiratory syndrome-coronavirus-(SARS-CoV-2), and increases in microbial resistance have made it essential to review the preventative approaches used during pre-antibiotic periods. Apart from low carbon emissions and energy, sustainable architecture for facilities, building designs, and digital modeling should incorporate design approaches to confront the impacts of communicable infections. This review aims to determine how architectural design can protect people and employees from harm; it models viewpoints to highlight the architects’ roles in combating coronavirus disease 2019 (COVID-19) and designing guidelines as a biomedical system for policymakers. The goals include exploring the hospital architecture evolution and the connection between architectural space and communicable infections and recommending design and digital modeling strategies to improve infection prevention and controls. Based on a wide-ranging literature review, it was found that design methods have often played important roles in the prevention and control of infectious diseases and could be a solution for combating the wide spread of the novel coronavirus or coronavirus variants or delta. 
  • 2.2K
  • 24 May 2022
Topic Review
Structure and Reaction Mechanism of Li-CO2 Batteries
A typical type of Li–CO2 battery consists of a porous cathode, electrolyte (liquid, solid), and lithium metal anode.
  • 2.2K
  • 22 Jun 2022
Topic Review
Pathophysiology of Cerebral Malaria and Treatment
Plasmodium falciparum causes over 90 percent of all malaria infections. Children under the age of 5 years and pregnant women were the most susceptible groups affected by malaria. The World Health Organization (WHO) has characterized malaria as severe and uncomplicated. Delays in the detection and treatment of an uncomplicated infection of P. falciparum malaria lead to complications of severe cerebral malaria (CM). CM is usually caused by P. falciparum, but Plasmodium vivax is rarely responsible for CM complications. CM is a severe neurological complication caused by Plasmodium falciparum infection, resulting in high mortality rates. CM is characterized by brain tissue hemorrhage, the accumulation of infected red blood cells and mononuclear cells in brain microvessels, and blood-brain barrier (BBB) disruption. 
  • 2.2K
  • 11 Jul 2022
Topic Review
Reactivity
In chemistry, reactivity is the impulse for which a chemical substance undergoes a chemical reaction, either by itself or with other materials, with an overall release of energy. Reactivity refers to: The chemical reactivity of a single substance (reactant) covers its behavior in which it: The chemical reactivity of a substance can refer to the variety of circumstances (conditions that include temperature, pressure, presence of catalysts) in which it reacts, in combination with the: The term reactivity is related to the concepts of chemical stability and chemical compatibility.
  • 2.2K
  • 02 Dec 2022
Topic Review
Conjugated Block Copolymers
Conjugated block copolymers (cBCPs) refer to block copolymers that contain one or more conjugated polymer segments. It can be a combination of several conjugated polymer segments with different properties, or it can be a combination of conjugated polymer segments and non-conjugated polymer segments. cBCPs not only maintain the advantages of high conductivity and mobility of conjugated polymers, but also demonstrate features of morphological versatility and tunability of block copolymers. cBCPs have a great potential application in organic solar cells, organic field effect transistors, organic light-emitting diodes and other fields.
  • 2.2K
  • 12 Jan 2021
Topic Review
Metabolic Reprogramming
Metabolic reprogramming is now recognized as a hallmark of cancer cells and supports cancer growth. Elucidating the underlying mechanisms of metabolic reprogramming in cancer cells may help identifying cancer targets and treatment strategies.
  • 2.2K
  • 20 Jan 2021
Topic Review
Liquid Biopsy
Liquid Biopsy (LB) is a novel method for cancer diagnosis performed by analyzing and sampling of non-solid biological tissues, obtained primarily from blood, but also from other body fluids such as urine, saliva and cerebrospinal fluid.
  • 2.2K
  • 25 May 2021
Topic Review
Commercially Non-Saccharomyces Yeasts for Winemaking
About 42 commercial products based on non-Saccharomyces yeasts are estimated as available on the market, being mostly pure cultures (79%), with a predominance of Torulaspora delbrueckii, Lachancea thermotolerans, and Metschnikowia pulcherrima. The others are multi-starter consortia that include non-Saccharomyces/Saccharomyces mixtures or only non-Saccharomyces species. Several commercial yeasts have shown adequate biocompatibility with S. cerevisiae in mixed fermentations, allowing an increased contribution of metabolites of oenological interest, such as glycerol, esters, higher alcohols, acids, thiols, and terpenes, among others, in addition to a lower production of acetic acid, volatile phenols, biogenic amines, or urea. The studies conducted to date demonstrate the potential of these yeasts to improve the properties of wine as an alternative and complement to the traditional S. cerevisiae. 
  • 2.2K
  • 07 Sep 2021
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