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Topic Review
Preventing Complications of Type-2 Diabetes
Diabetes is a major public health concern that is approaching epidemic proportions globally [1]. About 422 million people worldwide have diabetes, and 1.6 million deaths are directly attributed to diabetes each year. The most common is the type 2 diabetes. In the past three decades, the prevalence of type 2 diabetes has risen dramatically in countries of all income levels [2].
  • 841
  • 20 Aug 2021
Topic Review
Role of Artificial Intelligence in Healthcare
Artificial Intelligence (AI) has emerged as a transformative technology with immense potential in the field of medicine. By leveraging machine learning and deep learning, AI can assist in diagnosis, treatment selection, and patient monitoring, enabling more accurate and efficient healthcare delivery. The widespread implementation of AI in healthcare has the role to revolutionize patients’ outcomes and transform the way healthcare is practiced, leading to improved accessibility, affordability, and quality of care. 
  • 841
  • 16 Jan 2024
Topic Review
SARS-CoV-2 Mutational Pattern in Greece
From the 2500 clinical specimens, 220 were tested positive for SARS-CoV-2 indicating a prevalence of 8.8% among suspected cases. The RT-PCR Ct (Cycle threshold) Value ranged from 19 to 25 which corresponds to medium to high copy numbers of the virus in the positive samples.
  • 840
  • 21 Jan 2022
Topic Review
COVID-19 Vaccination in Developing Nations
Vaccines offer a hope toward ending the global pandemic caused by SARS-CoV2. Mass vaccination of the global population offers hope to curb the spread. Developing nations, however, face monumental challenges in procurement, allocation, distribution and uptake of vaccines. Inequities in vaccine supply are already evident with resource-rich nations having secured a large chunk of the available vaccine doses for 2021. Once supplies are made available, vaccines will have to be distributed and administered to entire populations—with considerations for individual risk level, remote geography, cultural and socio-economic factors. This would require logistical and trained personnel support that can be hard to come by for resource-poor nations. Several vaccines also require ultra-cold temperatures for storage and transport and therefore the need for specialized equipment and reliable power supply which may also not be readily available. Lastly, attention will need to be paid to ensuring adequate uptake of vaccines since vaccine hesitancy has already been reported for COVID vaccines. However, existing strengths of local and regional communities can be leveraged to provide innovative solutions and mitigate some of the challenges. Regional and international cooperation can also play a big role in ensuring equity in vaccine access and vaccination.
  • 839
  • 21 May 2021
Topic Review
Asthma and Chronic Obstructive Pulmonary Diseases
Asthma and chronic obstructive pulmonary disease (COPD) are prevalent chronic pulmonary diseases requiring ongoing self-management. According to the World Health Organization, approximately 339 million people worldwide have asthma, and over 65 million suffer from moderate-to-severe COPD, making it the third leading cause of death worldwide. Asthma typically starts early in life and is related to an allergy, whereas COPD is typically caused by air pollutants such as cigarette smoke or biomass fuel.
  • 839
  • 19 Nov 2021
Topic Review
Artificial Intelligence-Enhanced Point-of-Care Ultrasound in Low-Resource Settings
The utilization of ultrasound imaging for early visualization has been imperative in disease detection, especially in the first responder setting. Rapid advancements in the underlying technology of ultrasound have allowed for the development of portable point-of-care ultrasounds (POCUS) with handheld devices. The application of POCUS is versatile, as seen by its use in pulmonary, cardiovascular, and neonatal imaging, among many others. However, despite these advances, there is an inherent inability of translating POCUS devices to low-resource settings (LRS). To bridge these gaps, the implementation of artificial intelligence offers an interesting opportunity. This entry reviews recent applications of POCUS devices within LRS from 2016 to 2023, identifying the most commonly utilized clinical applications and areas where further innovation is needed. Furthermore, the researchers pinpoint areas of POCUS technologies that can be improved using state-of-art artificial intelligence technologies, thus enabling the widespread adoption of POCUS devices in low-resource settings.
  • 839
  • 04 Aug 2023
Topic Review
Quality of Life and IBD
Inflammatory bowel diseases (IBDs) are chronic disabling conditions, characterized by an unpredictable course with flare-ups and periods of remission, that frequently affect young people and require lifelong medical follow-up and treatment. For years, the main endpoints of IBD treatment had been clinical remission and response, followed by biomarker normalization and mucosal healing. In the last decades, different therapies have been proved to be effective to treat IBD and the use of patient reported outcome (PRO) have become more relevant. Therefore, health-related quality of life (HRQoL) that has been defined as the value assigned to the duration of life influenced by physical and mental health, has been suggested as an important endpoint for IBD management since multiple studies have shown that IBD impairs it, both physically and psychologically. 
  • 838
  • 13 Jul 2021
Topic Review
Impact of ERK5 on the Hallmarks of Cancer
Extracellular signal-regulated kinase 5 (ERK5) belongs to the mitogen-activated protein kinase (MAPK) family that consists of highly conserved enzymes expressed in all eukaryotic cells and elicits several biological responses, including cell survival, proliferation, migration, and differentiation.
  • 838
  • 14 Jan 2022
Topic Review
Mental Health and Healthy Habits in University Students
The move to university is a stage of constant psychosocial and academic changes, where anxious and depressive symptomatologies usually appear, in addition to the aggravation of previous mental health problems. The prevalence of psychopathology found was high, especially depressive and anxious pathologies. This incidence tends to be higher in undergraduates and/or Arts and Humanities, coinciding with those who tend to have poorer lifestyle habits. 
  • 837
  • 08 Feb 2022
Topic Review
Sustainable Employability (SE)
Employability should concern not only competence development but also the actual possibility and ability to use those competencies to create concrete personally valuable work opportunities, promoting workers’ wellbeing. This way of thinking takes shape in the concept of sustainable employability (SE).
  • 835
  • 23 Mar 2022
Topic Review
Digital Health Interventions by Clinical Pharmacists
Integrating digital interventions in healthcare has gained increasing popularity among clinical pharmacists (CPs) due to advances in technology. Although the impacts of telephone-based interventions on patients’ outcomes were decidedly mixed, web-based interventions and mobile apps exerted generally positive influences.
  • 834
  • 26 Jan 2022
Topic Review
Neonatal Sepsis and Hemostasis
Neonatal sepsis is considered critical for a significant increase in neonatal morbidity and mortality among hospitalized neonates. Neonatal sepsis, in most cases, coexists with coagulopathy, which can prove to be life-threatening.
  • 834
  • 08 Feb 2022
Topic Review
Relationship between Subjective Cognitive Complaints and Executive Functions
Subjective cognitive complaints correspond to a heterogeneous construct that frequently occurs in the early stages of older adult life. Despite being a common source of worry for middle-aged people, it can be underestimated when clinical and neuropsychological assessments discard any underlying pathological processes. Negative age stereotyping but also self-stereotyping can contribute to doing so. Although its diagnosis is a challenge, its implication as a possible predictor of mild cognitive impairment or dementia increases the interest in its early diagnosis and intervention.
  • 834
  • 21 Mar 2022
Topic Review
Dietary Intake Influences Vitamin Needs during Pregnancy
Numerous approaches demonstrate how nutritional intake can be sufficient to ensure the necessary supply of vitamins. However, it is evident that not all vitamins are contained in all foods, so it is necessary either to combine different food groups or to use a vitamin supplement to be well-fed. During pregnancy, deficiencies are often exacerbated due to increased energy and nutritional demands, causing adverse outcomes in mother and child. Micronutrient supplementation could lead to optimal pregnancy outcomes being essential for proper metabolic activities that are involved in tissue growth and functioning in the developing fetus. In order to establish adequate vitamin supplementation, various conditions should be considered, such as metabolism, nutrition and genetic elements.
  • 833
  • 14 Jun 2022
Topic Review
Effectiveness of COVID-19 Vaccines against Delta (B.1.617.2) Variant
The high transmissibility, mortality, and morbidity rate of the SARS-CoV-2 Delta (B.1.617.2) variant have raised concerns regarding vaccine effectiveness (VE). The short-term effectiveness of the Pfizer-BioNTech, Moderna, AstraZeneca, Bharat Biotech, and CoronaVac vaccines for the prevention of infection and the reduction in the severity of illness and hospitalizations associated with the Delta variant are supported. 
  • 832
  • 06 Jan 2022
Topic Review
Mobile Mammography Van in Missouri
Mobile mammography is a tool that has been used to reach underserved women in a diverse number of settings, including urban, rural, and mountain regions. The mobile mammography van, affiliated with Siteman Cancer Center Breast Health Center, acts as part of outreach efforts to increase breast screening rates in medically underserved communities including the St. Louis area (urban) as well as the rural Bootheel region of Missouri. The van reached a particularly vulnerable population that was mostly poor, uninsured, and with limited educational backgrounds regardless of their zip code of service. 
  • 832
  • 07 Jun 2022
Topic Review
Saliva and SARS-CoV-2
A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has become a global ongoing pandemic. This pandemic represents a great work risk for all health professionals, it includes dental professionals who are in constant contact with saliva, which represents one of the main routes of transmission of the disease. For several decades, saliva has been continuously studied as a means of assessing human health because it contains a wide variety of biomarkers. This is because saliva is a mixture of fluids from the salivary glands, crevicular fluids, desquamated epithelial cells, microorganisms, and a great number of proteins such as immunoglobulins, hormones, enzymes, and cytokines. Besides, a wide variety of oral tissues and cells are susceptible to infection by SARS-CoV-2 and that they express the ACE2 receptor, which is the main route of entry of the virus into cells, as well as the proteins TMPRSS and furin that contributes to the binding of the virus to the host cells.
  • 831
  • 14 Apr 2021
Topic Review
The Role of Insulin-like Growth Factor-1
The anterior pituitary also referred to as the adenohypophysis, originates from the oral ectoderm during embryonic development. It is enclosed by a network of blood capillaries originating from the hypothalamus, as a part of the hypophyseal portal system, responsible for transporting hormones from the hypothalamus to the anterior pituitary and from the anterior pituitary to the circulatory system. Hence, the hypophyseal portal system prevents hypothalamic hormones from entering directly into the circulation..
  • 830
  • 29 Mar 2022
Topic Review
Mediterranean Diet Adherence before/after BS
To the best of current knowledge, very few studies have been performed with regards to the effects of a Mediterranean diet on bariatric surgery outcomes.
  • 828
  • 08 Feb 2022
Topic Review
Computation of Fetal Kicking
Fetal movement has always been considered an essential indicator to evaluate the health of the unborn fetus. Many factors affect fetal movement. The frequency of fetal kicking is an important measurement of whether fetal development is progressing and healthy.
  • 828
  • 12 Apr 2022
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