Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Quercetin in Coronavirus Infections
The COVID-19 outbreak seems to be the most dangerous challenge of the third millennium due to its highly contagious nature. Amongst natural molecules for COVID-19 treatment, the flavonoid molecule quercetin (QR) is currently considered one of the most promising. QR is an active agent against SARS and MERS due to its antimicrobial, antiviral, anti-inflammatory, antioxidant, and some other beneficial effects. QR may hold therapeutic potential against SARS-CoV-2 due to its inhibitory effects on several stages of the viral life cycle.
  • 909
  • 06 Sep 2022
Topic Review
Effect of Sex Hormones on Migraine
Sex hormones and migraine are closely interlinked. Women report higher levels of migraine symptoms during periods of sex hormone fluctuation, particularly during puberty, pregnancy, and perimenopause. Ovarian steroids, such as estrogen and progesterone, exert complex effects on the peripheral and central nervous systems, including pain, a variety of special sensory and autonomic functions, and affective processing. A panel of basic scientists, when challenged to explain what was known about how sex hormones affect the nervous system, focused on two hormones: estrogen and oxytocin.
  • 908
  • 11 Mar 2024
Topic Review
Prescription Opioid Misuse
Prescription opioids are used for some chronic pain conditions. However, generally, long-term therapy has unwanted side effects which may trigger addiction, overdose, and eventually cause deaths. Opioid addiction and chronic pain conditions have both been associated with evidence of genetic and epigenetic alterations. Despite intense research interest, many questions about the contribution of epigenetic changes to this typology of addiction vulnerability and development remain unanswered.
  • 906
  • 06 Sep 2021
Topic Review
Cultural Safety for LGBTQIA+ People
Although the concept of "cultural safety" as its origins in indigenous nursing care, there is support and rationale for applying this concept for LGBTQIA+ people as a population who experience health disparities due to barriers to access equitable care. Building on Mukerjee and colleagues' 5 "P" tenets (partnerships, personal activities of daily living, prevention of harm, patient centering, and purposeful self-reflection), reviewed studies on components of culturally safe care for LGBTQIA+ people revealed five themes: power-enhancing care; inclusive healthcare institutions; continuous education and research; promotion of visibility; and individualised care.
  • 906
  • 12 Aug 2022
Topic Review
Sleep Disordered Breathing in Autism Spectrum Disorder
Sleep-disordered breathing is a significant problem affecting the pediatric population. These conditions can affect sleep quality and children’s overall health and well-being. Difficulties in social interaction, communication, and repetitive behavioral patterns characterize autism spectrum disorder. Sleep disturbances are common in children with ASD.
  • 906
  • 17 Oct 2023
Topic Review
COVID-19 during Gestation
COVID-19, the disease caused by SARS-CoV-2 has reached pandemic proportions worldwide, with considerable consequences for both health and the economy. In pregnant women, COVID-19 can alter the metabolic environment, iron metabolism, and oxygen supply of trophoblastic cells, and therefore have a negative influence on pregnant women and mechanisms of fetal development, with implications in the postnatal life. The purpose of this study was to investigate, for the first time, the effects of COVID-19 infection during pregnancy with regard to the oxidative/antioxidant status in mothers’ serum and placenta, together with placental iron metabolism. Results showed no differences in superoxide dismutase activity and placental antioxidant capacity. However, antioxidant capacity decreased in the serum of infected mothers. Catalase activity decreased in the COVID-19 group, while an increase in 8-hydroxy-2’-deoxyguanosine, hydroperoxides, 15-FT-isoprostanes, and carbonyl groups were recorded in this group. Placental vitamin D, E, and Coenzyme-Q10 also showed to be increased in the COVID-19 group. As for iron-related proteins, an up-regulation of placental DMT1, ferroportin-1, and ferritin expression was recorded in infected women. Due to the potential role of iron metabolism and oxidative stress in placental function and complications, further research is needed to explain the pathogenic mechanism of COVID-19 that may affect pregnancy, so as to assess the short-term and long-term outcomes in mothers’ and infants’ health.
  • 905
  • 28 Jan 2022
Topic Review
Vaccine and Monkeypox
The monkeypox virus (MPV) is a double-stranded DNA virus belonging to the Poxviridae family, Chordopoxvirinae subfamily, and Orthopoxvirus genus. It was called monkeypox because it was first discovered in monkeys, in a Danish laboratory, in 1958. Preventing the transmission and infection of MPV is associated with different challenges. The primary strategy of prevention would be vaccination. 
  • 905
  • 24 Oct 2022
Topic Review
Crowd Management during COVID-19 with Artificial Intelligence
COVID-19 requires crowded events to enforce restrictions, aimed to contain the spread of the virus. However, we have seen numerous events not observing these restrictions, thus becoming super spreader events. In order to contain the spread of a human to human communicable disease, a number of restrictions, including wearing face masks, maintaining social distancing, and adhering to regular cleaning and sanitization, are critical. These restrictions are absolutely essential for crowded events. Some crowded events can take place spontaneously, such as a political rally or a protest march or a funeral procession. Controlling spontaneous crowded events, like a protest march, political rally, celebration after a sporting event, or concert, can be quite difficult, especially during a crisis like the COVID-19 pandemic.
  • 900
  • 14 Jan 2022
Topic Review
Strategies to Manage an Outbreak for Avian Influenza
Avian influenza (AI) is a contagious disease among the poultry population with high avian mortality, which generates significant economic losses and elevated costs for disease control and outbreak eradication. AI is caused by an RNA virus part of the Orthomyxoviridae family; however, only Influenzavirus A is capable of infecting birds. AI pathogenicity is based on the lethality, signs, and molecular characteristics of the virus. Low pathogenic avian influenza (LPAI) virus has a low mortality rate and ability to infect, whereas the highly pathogenic avian influenza (HPAI) virus can cross respiratory and intestinal barriers, diffuse to the blood, damage all tissues of the bird, and has a high mortality rate.
  • 899
  • 26 Apr 2023
Topic Review
COVID-19 Pandemic on Employee Sleep Quality
COVID-19 was declared a pandemic on 11 March 2020, following a rapid, exponential increase in global cases. The COVID-19 pandemic was associated with depression, anxiety, sleep disturbances, distress, and suicidal ideations. This study explored the association of the COVID-19 pandemic and employee sleep quality at a healthcare technology and services organization.
  • 898
  • 07 Feb 2022
Topic Review
Immunosenescence in Cerebral Small Vessel Disease
Cerebral small vessel disease (CSVD) is one of the most important causes of vascular dementia. Immunosenescence and inflammatory response, with the involvement of the cerebrovascular system, constitute the basis of this disease. Immunosenescence identifies a condition of deterioration of the immune organs and consequent dysregulation of the immune response caused by cellular senescence, which exposes older adults to a greater vulnerability. A low-grade chronic inflammation status also accompanies it without overt infections, an “inflammaging” condition. The correlation between immunosenescence and inflammaging is fundamental in understanding the pathogenesis of age-related CSVD (ArCSVD). The production of inflammatory mediators caused by inflammaging promotes cellular senescence and the decrease of the adaptive immune response. Vice versa, the depletion of the adaptive immune mechanisms favours the stimulation of the innate immune system and the production of inflammatory mediators leading to inflammaging. Furthermore, endothelial dysfunction, chronic inflammation promoted by senescent innate immune cells, oxidative stress and impairment of microglia functions constitute, therefore, the framework within which small vessel disease develops: it is a concatenation of molecular events that promotes the decline of the central nervous system and cognitive functions slowly and progressively.
  • 898
  • 05 Sep 2022
Topic Review
Virtual Care
Virtual care extends beyond the walls of healthcare organizations to provide care at a distance. Virtual care encompasses the provision of care using advanced video conferencing technology to support remote care that takes place between patients and providers and the use of virtual reality technology to simulate care environments. Some of virtual care’s use in healthcare includes application to pain and anxiety management, virtual consultations and follow-up visits, rehabilitation and therapy services, outpatient clinics, and emergency services.
  • 897
  • 23 Nov 2021
Topic Review
Smoking Cessation Apps
Smoking cessation interventions are effective, but they are not easily accessible for all treatment-seeking smokers. Mobile health (mHealth) apps have been used in recent years to overcome some of these limitations. Smoking cessation apps can be used in combination with a face-to-face intervention (FFSC-Apps), or alone as general apps (GSC-Apps). Smartphone apps for smoking cessation could be promising tools. However, more research with an adequate methodological quality is needed to determine its effect. Nevertheless, smartphone apps’ high availability and attractiveness represent a great opportunity to reach large populations.
  • 897
  • 24 Dec 2021
Topic Review
Human-Animal Interaction in Animal-Assisted Interventions (AAI)s
Animal-assisted interventions (AAI)s are planned activities carried out in multidisciplinary teams with educational, therapeutic, and ludic-recreational purposes. The multidisciplinary and integrated character identifies AAIs as the expression of one health. While AAIs offer many advantages to subjects, they could be exposed to several zoonotic-pathogens transmissions. Therefore, positive animal welfare, as preventive medicine to avoid accidents or zoonotic transmissions, is a relevant aspect with implications for human and animal health and welfare. The knowledge of several pathogens causing zoonoses in the animal species employed during the AAIs, as well as the preventive measures aimed at reducing and/or preventing the risk, guarantee their safety for patients. 
  • 897
  • 18 May 2023
Topic Review
Time-Out with Young Children
Time-out is a component of many evidence-based parent training programmes for the treatment of childhood conduct problems. Existing comprehensive reviews suggest that time-out is both safe and effective when used predictably, infrequently, calmly and as one component of a collection of parenting strategies—i.e., when utilised in the manner advocated by most parent training programmes. However, this research evidence has been largely oriented towards the academic community and is often in conflict with the widespread misinformation about time-out within communities of parents, and within groups of treatment practitioners. This dissonance has the potential to undermine the dissemination and implementation of an effective suite of treatments for common and disabling childhood conditions. The parent-practitioner relationship is integral to the success of Parent-Child Interaction Therapy (PCIT), an evidence-based treatment which involves live coaching of parent(s) with their young child(ren). Yet this relationship, and practitioner perspectives, attitudes and values as they relate to time-out, are often overlooked. This practitioner review explores the dynamics of the parent-practitioner relationship as they apply to the teaching and coaching of time-out to parents. It also acknowledges factors within the clinical setting that impact on time-out’s use, such as the views of administrators and professional colleagues. The paper is oriented toward practitioners of PCIT but is of relevance to all providers of parent training interventions for young children.
  • 895
  • 11 Jan 2022
Topic Review
Selenium Status in Patients with Chronic Liver Disease
The potential role of selenium in preventing chronic liver diseases remains controversial. Both body selenium status and selenium intake were negatively associated with hepatitis, cirrhosis, and liver cancer. However, the associations for fatty liver diseases were conflicting and need to be established in prospective trials.
  • 895
  • 11 Mar 2022
Topic Review
Antibiotics Prescribing during COVID-19 Pandemic
It is axiomatic that hospital admissions increase risks of healthcare-associated infections (HCAIs), leading to a noticeable increase in antibiotic consumption. A recent study conducted on ICU patients in 88 countries highlighted that 70% of hospitalized patients receive at least one antibiotic during acute admission; of this cohort 54% developed a secondary bacterial infection that necessitated antibiotic therapy. In patients with severe disease, the WHO recommends the provision of antimicrobial therapy to prevent furthers infection complications, leading to severe acute respiratory distress syndrome (ARDS) and multi-organ failure.
  • 894
  • 27 Aug 2021
Topic Review
Whole Grain Consumption in Glycaemic Control
Whole grain consumption is beneficial for glucose metabolism in people with diabetes.
  • 893
  • 10 Jan 2022
Topic Review
Myocardial Infarction and Immuno-Inflammatory Response in CAE
Coronary artery ectasia (CAE) is a relatively common coronary angiographic finding, with an incidence of 1.5–5% and geographical variations in prevalence. CAE has been associated with a male predominance. Anatomically, CAE more frequently affects the right coronary artery and the proximal one third of the vessels.
  • 893
  • 16 May 2022
Topic Review
Health-Related Quality of Life (HRQoL)
HRQoL is a multi-dimensional concept that reflects the degree to which a health condition interferes with participation in and fulfillment of important life areas. HRQoL is intended to capture the composite degree of physical, physiologic, psychological, and social impairment resulting from symptom burden, patient-perceived disease severity, and treatment side effects.
  • 892
  • 01 Jul 2021
  • Page
  • of
  • 43
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback

Quick Survey

Encyclopedia MDPI is conducting a targeted survey to identify the specific barriers hindering efficient research. We invite you to spend 3 minutes defining the priorities for our next generation of structured knowledge tools.
Take Survey