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Topic Review
Lycium barbarum Deep-Processing Products of Fermentation
Lycium barbarum, a homology of medicine and food, contains many active ingredients including polysaccharides, polyphenol, betaine, and carotenoids, which has health benefits and economic value. The bioactive components in Lycium barbarum exhibit the effects of antioxidation, immune regulation, hypoglycemic effects, and vision improvement.
  • 1.3K
  • 04 Mar 2024
Topic Review
Mycotoxin Exposure and Children’s Health
The first 1000 days of life are very sensitive to any event that alters health programming, and they represent a window for intervention to improve population health. Pregnant women, fetuses, and infants are particularly vulnerable to exposure to food contaminated with mycotoxins. 
  • 1.2K
  • 29 Mar 2022
Topic Review
Swallow Detection with Acoustics and Accelerometric-Based Wearable Technology
Swallowing disorders, especially dysphagia, might lead to malnutrition and dehydration and could potentially lead to fatal aspiration. Benchmark swallowing assessments, such as videofluoroscopy or endoscopy, are expensive and invasive. Wearable technologies using acoustics and accelerometric sensors could offer opportunities for accessible and home-based long-term assessment. Identifying valid swallow events is the first step before enabling the technology for clinical applications. 
  • 1.2K
  • 09 Jan 2023
Topic Review
Nature’s Role in Outdoor Therapies
Outdoor therapies are intentional therapeutic processes that are (1) place-based, (2) feature active bodily engagement, and (3) recognize nature-human kinship. Significant variety exists in practice, from walk and talk therapy, to expedition-based wilderness therapy, to garden and animal-assisted therapies. These approaches have shown improvement across a wide range of social, emotional, physical, physiological, and psychological outcomes and populations.
  • 1.2K
  • 20 May 2021
Topic Review
The Association between Music and Language in Children
Music and language are two complex systems that specifically characterize the human communication toolkit.
  • 1.2K
  • 05 Jun 2023
Topic Review
Weight Loss
Overweight and obesity are related pathological conditions with a significant impact at the cardiovascular, metabolic, musculoskeletal, and oncological levels, representing a significant global public health problem. The traditionally proposed therapeutic approaches act at the nutritional, psychological, lifestyle (abolishing sedentary lifestyle and promoting physical exercise), and pharmacological levels, in combination with the consumption of food supplements.
  • 1.2K
  • 29 Mar 2022
Topic Review
Biosensors and Microfluidic Biosensors
Biosensors are ubiquitous in a variety of disciplines, such as biochemical, electrochemical, agricultural, and biomedical areas. They can integrate various point-of-care applications, such as in the food, healthcare, environmental monitoring, water quality, forensics, drug development, and biological domains. Multiple strategies have been employed to develop and fabricate miniaturized biosensors, including design, optimization, characterization, and testing. In view of their interactions with high-affinity biomolecules, they find application in the sensitive detection of analytes, even in small sample volumes. Among the many developed techniques, microfluidics have been widely explored; these use fluid mechanics to operate miniaturized biosensors. The currently used commercial devices are bulky, slow in operation, expensive, and require human intervention; thus, it is difficult to automate, integrate, and miniaturize the existing conventional devices for multi-faceted applications. Microfluidic biosensors have the advantages of mobility, operational transparency, controllability, and stability with a small reaction volume for sensing. 
  • 1.2K
  • 05 Aug 2022
Topic Review
The Influence of Heavy Metal
There are a multitude of sources of heavy metal pollution which have unwanted effects on this super organism, the soil, which is capable of self-regulation, but limited. Living a healthy life through the consumption of fruits and vegetables, mushrooms, edible products and by-products of animal origin, honey and bee products can sometimes turn out to be just a myth due to the contamination of the soil with heavy metals whose values, even if they are below accepted limits, are taken up by plants, reach the food chain and in the long term unbalance the homeostasis of the human organism. Plants, these miracles of nature, some with the natural ability to grow on polluted soils, others needing a little help by adding chelators or amendments, can participate in the soil detoxification of heavy metals through phytoextraction and phytostabilization.
  • 1.2K
  • 04 Apr 2023
Topic Review
Skin Cancer in the Ear: Signs and Symptoms
Learn the signs and symptoms of skin cancer in the ear, from unusual growths to persistent irritation. Understand what to watch for and when to seek help.
  • 1.2K
  • 13 Nov 2024
Topic Review
Health Information Systems for Healthcare
Health information system deployment has been driven by the transformation and digitalization confronting healthcare. The need and potential of these systems within healthcare have been tremendously driven by the global instability that has affected several interrelated sectors. Accordingly, many research studies have reported on the inadequacies of these systems within the healthcare arena, which have distorted their potential and offerings to revolutionize healthcare.
  • 1.2K
  • 11 Apr 2023
Topic Review
Role of Glutathione in Food and Human Diseases
Glutathione is a naturally occurring compound that plays a crucial role in the cellular response to oxidative stress through its ability to quench free radicals, thus mitigating the risk of potential damage, including cell death. While glutathione is endogenously present in different plants and animal cells, their concentration varies considerably. The alteration in glutathione homeostasis can be used as a potential marker for human diseases. In the case of the depletion of endogenous glutathione, exogenous sources can be used to replenish the pool. To this end, both natural and synthetic glutathione can be used. 
  • 1.1K
  • 13 Apr 2023
Topic Review
Monoclonal Antibodies (mAbs)  Application in Cancer Immunotherapy
Clinical application of monoclonal antibodies (mAbs) immunotherapy to treat and manage many cancers has been successfully established in recent years. Primary solid tumors have been effectively treated and managed with antibody-chemotherapy conjugates. The development and establishment of therapeutic monoclonal antibodies require a complete understanding of tumor heterogeneity, intra-tumoral factors, protein engineering, and the interaction between cancer cells and the immune system. Researchers have now developed mAbs that target specific antigens in cancer cells and inhibit signals responsible for tumor growth and invasion. Monoclonal antibodies are simply synthetic proteins employed as immunotherapies to treat and manage some, but not all, cancers. Monoclonal antibodies are produced in four different forms, including murine, chimeric, humanized, and human.
  • 1.1K
  • 09 Sep 2022
Topic Review
Risk Factors for Testicular Cancer
A large piece of knowledge suggests that most testicular cancers originate from a potential noxa during fetal life. Nevertheless, the environment, familial history, ethnicity as well as diet and occupational exposures are other important actors involved in testis carcinogenesis. 
  • 1.1K
  • 19 Jun 2023
Topic Review
Sleep Duration and Waking Activities
Optimal sleep duration is crucial as both short and long sleep duration are associated with physical and mental health problems. For example, sleep duration that is considered to be too short has been linked with an increased risk of obesity, hypertension, cardiovascular disease, and type II diabetes, whereas sleep duration that is too long has been associated with an increased risk of poor health-related quality of life, multiple sclerosis, cardiovascular disease, and stroke.
  • 1.1K
  • 24 Jun 2021
Topic Review
Ramadan Fasting and Offspring Health
Ramadan is one of the five pillars of Islam, during which fasting is obligatory for all healthy individuals. Although pregnant women are exempt from this Islamic law, the majority nevertheless choose to fast. The association between Ramadan fasting and health outcomes of offspring is not supported by strong evidence. To further elucidate the effects of Ramadan fasting, larger prospective and retrospective studies with novel designs are needed. 
  • 1.1K
  • 26 Oct 2021
Topic Review
Current Status of Internet Gaming Disorder
The World Health Organization recognizes internet gaming disorder (IGD) as a disorder that causes problems in daily life as a result of excessive interest in online games. The causes of IGD have become more apparent. Because of prolonged exposure to games, the mechanisms controlling the reward system, such as the prefrontal cortex, limbic system, and amygdala of the cerebrum, do not function properly in IGD. This mechanism is similar to that of various behavioral addictions, such as gambling addiction. IGD is particularly risky in children and adolescents because it easily causes brain dysfunction, especially in the developing brain.
  • 1.1K
  • 15 Aug 2022
Topic Review
Omega-3 PUFA in Pediatric Cancer
Epidemiological literature suggests a protective effect of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) against cancer. They are attributed to have significant anti-inflammatory properties, and are reported to directly inhibit carcinogenesis and tumor expansion, whilst also reducing the risk for secondary complications, thus representing a promising approach for adjunctive chemotherapy treatment. At the same time, the incidence of malnutrition amongst children with cancer is high and both under- and overnutrition are associated with detrimental consequences, including increased risks for morbidity and mortality, early relapse rates, and a higher prevalence of secondary complications during treatment. Taken together with the benefits of n-3 PUFA supplementation, an enhancement of the nutritional status is a potentially modifiable prognostic factor in pediatric oncology.
  • 1.1K
  • 08 Jun 2021
Topic Review
Renin-Angiotensin System and COVID-19
The renin–angiotensin system (RAS), an essential enzymatic cascade involved in maintaining blood pressure and electrolyte balance, is involved in the pathogenicity of COVID-19, since the angiotensin-converting enzyme II (ACE2) acts as the cellular receptor for SARS-CoV-2 in many human tissues and organs. In fact, the viral entrance promotes a downregulation of ACE2 followed by RAS balance dysregulation and an overactivation of the angiotensin II (Ang II)–angiotensin II type I receptor (AT1R) axis, which is characterized by a strong vasoconstriction and the induction of the profibrotic, proapoptotic and proinflammatory signalizations in the lungs and other organs. This mechanism features a massive cytokine storm, hypercoagulation, an acute respiratory distress syndrome (ARDS) and subsequent multiple organ damage.
  • 1.1K
  • 25 Nov 2021
Topic Review
Romanian Healthcare System—Structure and Role in Social Prescribing
Social prescribing initiatives are tailored coaching programs created to assist participants in improving their personal circumstances and might constitute a creative way to enhance public and preventive health as researchers work toward providing universal financially sustainable healthcare.
  • 1.1K
  • 04 Aug 2023
Biography
Dr. (Prof.) Abhyudaya Verma
Dr. (Prof.) Abhyudaya Verma is an Indian endocrinologist and the founder of Superspeciality Endocrinology & Women cAre centre (SEWA), Indore, Madhya Pradesh, India. Dr. (Prof.) Abhyudaya Verma was born in Indore, Madhya Pradesh. He pursued his MBBS from M. S. Ramaiah Medical College (MSRMC), Bangalore in 1999 thereafter completed his MD (General Medicine) from Rajiv Gandhi University of Health S
  • 1.1K
  • 27 Feb 2023
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