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Topic Review
Ascorbic Acid-Induced Reactions
Ascorbic acid is the most well-known vitamin found in different types of food. It has tremendous medical applications in several different fields such as in pharmaceuticals, cosmetics, and in organic synthesis. Ascorbic acid can be used as a substrate or mediator in organic synthesis. In this review, we report ascorbic acid-catalyzed reactions in organic synthesis. Several examples are included in this review to demonstrate that ascorbic acid is a versatile catalyst for the synthesis of diverse organic compounds. Reactions catalyzed by ascorbic acid are performed in organic or aqueous media. The readily available and easy handling features of ascorbic acid make these procedures highly fascinating.
  • 5.0K
  • 25 Nov 2020
Topic Review
Messiah
In Abrahamic religions, a messiah or messias (Hebrew: מָשִׁיחַ‎, romanized: māšîaḥ; Greek: μεσσίας, romanized: messías, Arabic: مسيح) is a saviour or liberator of a group of people. The concepts of mashiach, messianism, and of a Messianic Age originated in Judaism, and in the Hebrew Bible; a mashiach (messiah) is a king or High Priest traditionally anointed with holy anointing oil. Messiahs were not exclusively Jewish: the Book of Isaiah refers to Cyrus the Great, king of the Achaemenid Empire, as a messiah for his decree to rebuild the Jerusalem Temple. Ha mashiach (המשיח, 'the Messiah', 'the anointed one'),[lower-alpha 1] often referred to as melekh mashiach (מלך המשיח 'King Messiah'), is to be a human leader, physically descended from the paternal Davidic line through King David and King Solomon. He is thought to accomplish predetermined things in only one future arrival, including the unification of the tribes of Israel, the gathering of all Jews to Eretz Israel, the rebuilding of the Temple in Jerusalem, the ushering in of a Messianic Age of global universal peace, and the annunciation of the world to come. In Christianity, the Messiah is called the Christ, from Greek: χριστός, romanized: khristós, translating the Hebrew word of the same meaning. The concept of the Messiah in Christianity originated from the Messiah in Judaism. However, unlike the concept of the Messiah in Judaism, Jesus is considered by Christians additionally to be the Son of God. Christ became the accepted Christian designation and title of Jesus of Nazareth, because Christians believe that the messianic prophecies in the Old Testament were fulfilled in his mission, death, and resurrection. These specifically include the prophecies of him being descended from the Davidic line, and being declared King of the Jews which happened on the day of his crucifixion. They believe that Christ will fulfill the rest of the messianic prophecies, specifically that he will usher in a Messianic Age and the world to come at his Second Coming. Some Christian denominations, such as Catholicism, instead believe in amillenialist theology, but the Catholic Church has not adopted this term. In Islam, Jesus was a prophet and the Masîḥ (مسيح), the Messiah sent to the Israelites, and he will return to Earth at the end of times, along with the Mahdi, and defeat al-Masih ad-Dajjal, the false Messiah. In Ahmadiyya theology, these prophecies concerning the Mahdi and the second coming of Jesus have been fulfilled in Mirza Ghulam Ahmad (1835–1908), the founder of the Ahmadiyya Movement, and the terms 'Messiah' and 'Mahdi' are synonyms for one and the same person. In Chabad messianism, Yosef Yitzchak Schneersohn (r. 1920–1950), sixth Rebbe (spiritual leader) of Chabad Lubavitch, and Menachem Mendel Schneerson (1902–1994), seventh Rebbe of Chabad, are Messiah claimants. Resembling early Christianity, the deceased Schneerson is believed to be the Messiah among some adherents of the Chabad movement; his second coming is believed to be imminent.
  • 5.0K
  • 11 Nov 2022
Topic Review
Biosynthesis Pathway and Metabolism of Isoflavones
Isoflavones have been widely studied and have attracted extensive attention in fields ranging from chemotaxonomy and plant physiology to human nutrition and medicine. Isoflavones are often divided into three subgroups: simple O-substituted derivatives, prenylated derivatives, and glycosides. Simple O-substituted isoflavones and their glycosides, such as daidzein (daidzin), genistein (genistin), glycitein (glycitin), biochanin A (astroside), and formononetin (ononin), are the most common ingredients in legumes and are considered as phytoestrogens for daily dietary hormone replacement therapy due to their structural similarity to 17-β-estradiol. On the basis of the known estrogen-like potency, these above isoflavones possess multiple pharmacological activities such as antioxidant, anti-inflammatory, anticancer, anti-angiogenetic, hepatoprotective, antidiabetic, antilipidemic, anti-osteoporotic, and neuroprotective activities. 
  • 5.0K
  • 22 Sep 2022
Topic Review
Cheese By-Products
Cheese whey (CW) is nowadays recognized as a source of functional and bioactive compounds, especially proteins and peptides. However, a large proportion of the whey produced worldwide is still not valorized. This results from the fact that small and medium size dairy industries lack dimension to make the necessary investments for CW valorization. In some countries such as Portugal, Spain, Italy and Turkey, CW is employed in the production of whey cheeses. The liquid remaining after whey cheese production represents more than 90% of the original whey and is called second cheese whey (SCW). SCW is a poorly studied by-product and there is little interest in its recovery. SCW is a poorly studied by-product and there is little interest in its recovery. Some authors studied the use of SCW for conversion into biofuel and as a biotechnological substrate for fermented products while others studied its potential for the production of fermented drinks. However, half of CW and almost all SCW are not valorized for human consumption. This review presents several alternatives for the valorization of both by-products.
  • 5.0K
  • 20 May 2021
Topic Review
Fountain (Duchamp)
Fountain is a readymade sculpture produced by Marcel Duchamp in 1917: a porcelain urinal signed "R.Mutt". In April 1917, an ordinary piece of plumbing chosen by Duchamp was rotated 90 degrees on its axis and submitted for an exhibition of the Society of Independent Artists, the first annual exhibition by the Society to be staged at The Grand Central Palace in New York. Fountain was not rejected by the committee but it was removed from the show area, since Society rules stated that all works would be accepted from artists who paid the fee. Following that removal, Fountain was photographed at Alfred Stieglitz's studio, and the photo published in The Blind Man. The original has been lost. The work is regarded by art historians and theorists of the avant-garde as a major landmark in 20th-century art. Sixteen replicas were commissioned by Duchamp in the 1950s and 1960s and made to his approval. Some scholars have suggested that the original work was by a female artist rather than Duchamp, but this is a minority view among historians.
  • 5.0K
  • 28 Nov 2022
Topic Review
Mechanisms of Hydrogen Embrittlement
Hydrogen embrittlement (HE) is a broadly recognized phenomenon in metallic materials. If not well understood and managed, HE may lead to catastrophic environmental failures in vessels containing hydrogen, such as pipelines and storage tanks. HE can affect the mechanical properties of materials such as ductility, toughness, and strength, mainly through the interaction between metal defects and hydrogen. Various phenomena such as hydrogen adsorption, hydrogen diffusion, and hydrogen interactions with intrinsic trapping sites like dislocations, voids, grain boundaries, and oxide/matrix interfaces are involved in this process.
  • 5.0K
  • 05 Mar 2024
Topic Review
Evolution of Digital Twins
A digital twin can be described as a digital replica of a real-world entity. It simulates the physical state and maybe the biological state and behavior of the real-world entity based on input data. It helps in predicting, optimizing, and improving decision making. It has revolutionized the industrial world, particularly the manufacturing industry, construction and healthcare sector, smart cities, and energy industry. 
  • 5.0K
  • 13 May 2021
Topic Review
Messerschmitt Me 323
The Messerschmitt Me 323 Gigant ("Giant") was a German military transport aircraft of World War II. It was a powered variant of the Me 321 military glider and was the largest land-based transport aircraft of the war. A total of 213 are recorded as having been made, 15 being converted from the Me 321.
  • 5.0K
  • 17 Oct 2022
Topic Review
Modern Computing in Iran
Iran’s modern computing history can be divided into four distinct periods: (1) Computers were first introduced to Iran in 1962. As a result, the introduction of computers in Iran occurred approximately ten years after introducing computers in developed countries. (2) Computer development, Iran’s computer development era began in 1971 and lasted until 1981. This path was followed by a lot of competition to buy hardware, introduce massive software systems, recruit more manpower, and follow rigorous programs based on the country’s technological realities. (3) Computer revisit: As a result of the Islamic Revolution, improvements and innovations in computers occurred, and a series of general reviews were conducted until 1980. (4) Technological maturity and growth in Iran: Following the reopening of universities in 1983, the next stage of computer development began, with software and hardware becoming widely available. The Persian language and script processing is among this century’s most important works.
  • 5.0K
  • 29 Aug 2022
Topic Review
Psychoneuroendocrineimmunology (PNEI)
Psychoneuroendocrineimmunology (PNEI) brings together knowledge acquired since the 1930s from endocrinology, immunology, neuroscience, and psychology. With PNEI, a model of research and interpretation of health and disease is emerging, which sees the human body as a structured and interconnected unit, where the psychological and biological systems are mutually coordinated. In the PNEI view, many factors could influence mental health, with the endocrine system involved in mediating the effects of environmental stress on mental health and inflammation in the onset and course of psychiatric disorders as a result of individual and collective conditions and behaviors.  PNEI paradigm configures the possibilities of going beyond the historical and philosophical contrast between mind and body, as well as the scientific antithesis of the twentieth century, between medicine and psychology, overcoming their respective reductionism, which assigns the body to the first and the psyche to the second.   
  • 5.0K
  • 11 Aug 2021
Topic Review
Sorbent-Based Microextraction of Natural Toxins from Food Samples
Natural toxins are chemical substances that are not toxic to the organisms that produce them, but which can be a potential risk to human health when ingested through food. Thus, it is of high interest to develop advanced analytical methodologies to control the occurrence of these compounds in food products. Current trends in sample preparation involve moving towards “greener” approaches by scaling down analytical operations, miniaturizing the instruments and integrating new advanced materials as sorbents. The combination of these new materials with sorbent-based microextraction technologies enables the development of high-throughput sample preparation methods, which improve conventional extraction and clean-up procedures.
  • 5.0K
  • 05 Nov 2021
Topic Review
Guccifer 2.0
"Guccifer 2.0" is a persona which claimed to be the hacker(s) that hacked into the Democratic National Committee (DNC) computer network and then leaked its documents to the media, the website WikiLeaks, and a conference event. Some of the documents "Guccifer 2.0" released to the media appear to be forgeries cobbled together from public information and previous hacks, which had been mixed with disinformation. According to indictments in February 2018, the persona is operated by Russian military intelligence agency GRU. On July 13, 2018, Special Counsel Robert Mueller indicted 12 GRU agents for allegedly perpetrating the cyberattacks. The U.S. Intelligence Community concluded that some of the genuine leaks from "Guccifer 2.0" were part of a series of cyberattacks on the DNC committed by two Russian military intelligence groups, and that "Guccifer 2.0" is actually a persona created by Russian intelligence services to cover for their interference in the 2016 U.S. presidential election. This conclusion is based on analyses conducted by various private sector cybersecurity individuals and firms, including CrowdStrike, Fidelis Cybersecurity, FireEye's Mandiant, SecureWorks, ThreatConnect, Trend Micro, and the security editor for Ars Technica. The Russian government denies involvement in the theft, and "Guccifer 2.0" denied links to Russia. WikiLeaks founder Julian Assange said multiple parties had access to DNC emails and that there was "no proof" Russia was behind the attack. In March 2018, Special Counsel Robert Mueller took over investigation of Guccifer 2.0 from the FBI while it was reported that forensic determination had found the Guccifer 2.0 persona to be a "particular military intelligence directorate (GRU) officer working out of the agency's headquarters on Grizodubovoy Street in Moscow".
  • 5.0K
  • 10 Oct 2022
Topic Review
Corn Processing by-Products
As an important food crop, corn has an important impact on people’s lives. The processing of corn produces many by-products, such as corn gluten meal, corn husk, and corn steep liquor, which are rich in protein, oil, carbohydrates, and other nutrients, all of which are inexpensive. Their accumulation in large quantities during the production process not only results in a burden on the environment but also the loss of potentially valuable food materials that can be processed. In fact, the by-products of corn processing have been partially used in functional foods, nutrients, feed, and other industries. There is no doubt that the secondary utilization of these by-products can not only solve the problem of waste pollution caused by them, but also produce high value-added products and improve the economic benefits of corn. 
  • 5.0K
  • 01 Dec 2022
Topic Review
Application of Natural Coagulants in Water Treatment
The most popular and conventional method for water treatment (WT)  is the use of chemical-based coagulants including ferric chloride (FeCl3), alum (AlCl3), synthetic polymers (polyacrylamide), and poly aluminum. However, the use of this approach is not sustainable as it leads to the production of a large volume of non-biodegradable sludge. Natural coagulants, on the other hand, serve as an alternative sustainable strategy for the removal of turbidity and WT, as they are cheap, safe, and biodegradable. Natural coagulants are derived from three major sources, which include plants, animals, and microorganisms.
  • 5.0K
  • 02 Dec 2022
Topic Review
Aircraft Livery
An aircraft livery is a set of comprehensive insignia comprising color, graphic, and typographical identifiers which operators (airlines, governments, Air force s and occasionally private and corporate owners) apply to their aircraft. As aircraft liveries evolved in the years after the Second World War, they became a leading subset of the emerging disciplines of corporate identity and branding and among the most prominent examples of fashion. They have provided an arena for the work of distinguished designers and eminent lay people like Raymond Loewy, Alexander Girard, and Jacqueline Kennedy Onassis. The term is an adaptation of the word livery: the uniform-style clothing worn by servants of wealthy families and government representatives until the early/mid-20th century. With the advent of stagecoaches, railway trains, and steamships, the term livery spread to their decoration. Since the 1950s, elements of airline liveries permeated ground vehicles, advertising, proprietary airport furniture, airline promotional materials and aircrew uniforms in an increasingly integrated manner, spreading to airline websites in the 1990s. Since the 1950s and 60s, aircraft liveries have usually been uniform livery across an entire fleet. One-off custom-designs might be applied from time to time to individual fleet members to highlight set occasions.
  • 5.0K
  • 21 Oct 2022
Topic Review Peer Reviewed
Age-Friendly Built Environment
Age-friendly built environments have been promoted by the World Health Organisation (WHO, Geneva, Switzerland) under the Global Age-friendly Cities (AFC) movement in which three domains are related to the built environment. These are: housing, transportation, outdoor spaces and public buildings. The aim is to foster active ageing by optimising opportunities for older adults to maximise their independent living ability and participate in their communities to enhance their quality of life and wellbeing. An age-friendly built environment is inclusive, accessible, respects individual needs and addresses the wide range of capacities across the course of life. Age-friendly housing promotes ageing in familiar surroundings and maintains social connections at the neighbourhood and community levels. Both age-friendly housing and buildings provide barrier-free provisions to minimise the needs for subsequent adaptations. Age-friendly public and outdoor spaces encourage older adults to spend time outside and engage with others against isolation and loneliness. Age-friendly public transport enables older adults to get around and enhances their mobility. For achieving an age-friendly living environment, a holistic approach is required to enable independent living, inclusion and active participation of older adults in society. The eight domains of the AFC movement are not mutually exclusive but overlap and support with one another.
  • 5.0K
  • 13 Apr 2022
Topic Review
CYP3A4
CYP3A4 is a low specificity isoenzyme of the CYPs family, which contributes to the metabolism of approximately 50% of all marketed drugs. Induction or inhibition of CYP3A4 activity results in the varied oral bioavailability and unwanted drug-drug, drug-food, and drug-herb interactions.
  • 5.0K
  • 01 Sep 2021
Topic Review
Gyro-Stabilized Camera Systems
Gyro-stabilized camera systems use modern electronic position data to correct for movements of the platforms they are mounted on to enable a high degree of stabilization. The systems often use a multi-axis gyro stabilization to enable the use of zoom lenses and high definition capture, despite the high amounts of vibrations and movements in aircraft, helicopters or other vehicles. The applications range from security and military operations, law enforcement, ENG, sports broadcasting documentary, natural history, and feature film productions..
  • 5.0K
  • 14 Oct 2022
Topic Review Peer Reviewed
Novel Bioactive Extraction and Nano-Encapsulation
An extraction technology works on the principle of two consecutive steps that involves mixture of solute with solvent and the movement of soluble compounds from the cell into the solvent and its consequent diffusion and extraction. The conventional extraction techniques are mostly based on the use of mild/high temperatures (50–90 °C) that can cause thermal degradation, are dependent on the mass transfer rate, being reflected on long extraction times, high costs, low extraction efficiency, with consequent low extraction yields. Due to these disadvantages, it is of interest to develop non-thermal extraction methods, such as microwave, ultrasounds, supercritical fluids (mostly using carbon dioxide, SC-CO2), and high hydrostatic pressure-assisted extractions which works on the phenomena of minimum heat exposure with reduced processing time, thereby minimizing the loss of bioactive compounds during extraction. Further, to improve the stability of these extracted compounds, nano-encapsulation is required. Nano-encapsulation is a process which forms a thin layer of protection against environmental degradation and retains the nutritional and functional qualities of bioactive compounds in nano-scale level capsules by employing fats, starches, dextrins, alginates, protein and lipid materials as encapsulation materials.
  • 5.0K
  • 13 Apr 2022
Topic Review
Sustainable Energy Consumption in Developing Country
Since energy consumption in developing countries has increased significantly, motivating energy-saving habits among citizens is an important issue both from the academic and industrial perspectives.
  • 5.0K
  • 09 Aug 2022
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