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Topic Review
A Comprehensive Assessment of Carob, C. siliqua L.
The carob tree (C. siliqua L.) is an evergreen perennial tree from the Fabaceae (Leguminosae) family. Originating in the Mediterranean region, it now populates many parts of the world, including North and South America, Africa, and Australia. The tree grows up to 15 m tall and boasts long, dark green leathery leaves.
  • 1.4K
  • 07 Oct 2023
Topic Review
Brain Functional Correlates of Resting Hypnosis and Hypnotizability
Resting-state functional magnetic resonance imaging (fMRI) and structural MRI investigations offer complementary insights into the distinctive frontal functioning associated with high hypnotizability. Studies indicate that individuals with high hypnotizability display more pronounced reductions in activation of the medial prefrontal or dorsal anterior cingulate cortex following neutral hypnotic induction than their low hypnotizable ones. Moreover, research has disclosed that induction-specific reductions in the activation of the Default Mode Network (DMN) regions correspond to spontaneous changes in cognitive and perceptual states, and the state of attentional absorption during a hypnotic induction has been associated with reduced DMN activity and increased prefrontal attentional system activity.
  • 1.4K
  • 04 Feb 2024
Topic Review
Polyurethanes and Green Chemistry
Polyurethanes are most often called “green” when they contain natural, renewable additives in their network or chemical structure, such as mono- and polysaccharides, vegetable oils, polyphenols, or various compounds derived from agro-waste white biotechnology. The use of these natural substrates is in line with the principles of green chemistry. However, other principles among all 12 can also be used in the production of polyurethanes.
  • 1.4K
  • 11 Nov 2021
Topic Review
Influence of Customer Mistreatment on Hospitality Employee Responses
Customer mistreatment is a reflection of poor customer behaviors, which include speaking loudly, verbal abuse, making unfair demands, skipping a queue, and other disrespectful behaviors. Customer mistreatment may be an unavoidable issue for the hospitality industry.
  • 1.4K
  • 10 Oct 2023
Topic Review
Co-CeO2 Catalyzed Water-Gas Shift Reaction
Co-CeO2 catalysts were synthesized by the different methods to derive the optimal synthetic method and to investigate the effect of the preparation method on the physicochemical characteristics of Co-CeO2 catalysts in the high-temperature water-gas shift (HTS) reaction. Co-CeO2 catalyst synthesized by a sol-gel method features the strong metal to support interaction and the largest amount of oxygen vacancies compared to other catalysts, which affects the catalytic activity. As a result, Co-CeO2 catalyst synthesized by the sol-gel method exhibited the highest WGS activity among the prepared catalysts, even in the severe conditions (high CO concentration: ~38% in dry basis and high gas hourly space velocity: 143,000 h−1).
  • 1.4K
  • 30 Oct 2020
Topic Review
Digital Agriculture Food and Wine
Digital Agriculture, Food, and Wine deals with the implementation and integration of digital data, sensors, technology, and tools on agricultural applications from the farm to consumers. These technologies can range from big data, sensor technology, sensor networks, remote sensing, robotics, unmanned aerial vehicles (UAV). Data processing is performed using new and emerging technologies, such as computer vision, machine learning, and artificial intelligence, among others. The latest advances made by the Digital Agriculture Food and Wine Sciences group (DAFW) from The University of Melbourne deals with crop monitoring/decision making, assessment of quality of produces, non-invasive sensory analysis for consumer perception assessment, and animal stress and welfare assessments.
  • 1.4K
  • 18 Feb 2021
Topic Review
Periodontitis Treatment
Fabrication of biomaterial that mimics a suitable biological microenvironment is still a major challenge in the field of periodontitis treatment. Hence, in this report, we presented for the first time the fabrication of a novel biomaterial 3D matrix using collagen combined with sodium alginate and titanium oxide (TiO2) to recreate the in-vivo microenvironment and to act as a platform for the culture of human periodontal ligament fibroblasts (HPLF) towards osteogenic differentiation.
  • 1.4K
  • 29 Oct 2020
Topic Review
Multiple Myeloma
Multiple myeloma (MM), characterized by malicious clonal explanation of plasma cells in the bone marrow with creation of monoclonal gammopathy, is the second most prevalent hematologic malignancy in adults. It accounts for approximately 13% of all hematologic malignancies and 1% of all cancers in the world, with a median age of onset of 69 years [1][2]. 
  • 1.4K
  • 27 Oct 2020
Topic Review
Ribozymes and Riboswitches in S.cerevisiae
Among noncoding RNA sequences, riboswitches and ribozymes have attracted the attention of the synthetic biology community as circuit components for translation regulation. When fused to aptamer sequences, ribozymes and riboswitches are enabled to interact with chemicals. Therefore, protein synthesis can be controlled at the mRNA level without the need for transcription factors. Potentially, the use of chemical-responsive ribozymes/riboswitches would drastically simplify the design of genetic circuits. 
  • 1.4K
  • 04 Jun 2021
Topic Review
Lignans in Disorders Related to Oxidative Stress/Inflammation
Plant lignans exhibit a wide range of biological activities, which makes them the research objects of potential use as therapeutic agents. They provide diverse naturally-occurring pharmacophores and are available for production by chemical synthesis. A large amount of accumulated data indicates that lignans of different structural groups are apt to demonstrate both anti-inflammatory and antioxidant effects, in many cases, simultaneously.
  • 1.4K
  • 01 Jun 2022
Topic Review
HDL-Mediated Cholesterol Trafficking in the Central Nervous System
Alzheimer’s disease (AD) is characterized by the accumulation of extracellular amyloid beta (Aβ) and abnormally hyperphosphorylated intracellular tau filaments in neurons. Cholesterol metabolism has been extensively implicated in the pathogenesis of AD through biological, epidemiological, and genetic studies, with the APOE gene being the most reproducible genetic risk factor for the development of AD. The apolipoprotein E (ApoE) 4  genotype seems to be a disruptive element in high-density lipoprotein (HDL)-like-mediated cholesterol transport through the brain. 
  • 1.4K
  • 30 Aug 2022
Topic Review
Impact of Lockdown on PM Charecterisitcs
Air is a diverse mixture of gaseous and suspended solid particles. Several new substances are being added to the air daily, polluting it and causing human health effects. Particulate matter (PM) is the primary health concern among these air toxins. The World Health Organization (WHO) addressed the fact that particulate pollution affects human health more severely than other air pollutants. The spread of air pollution and viruses, two of the millennium’s most serious concerns, have been linked closely. 
  • 1.4K
  • 26 Oct 2022
Topic Review
Endodontic–Periodontal Lesions
Endodontic–periodontal lesions (EPLs) are chronic inflammatory lesions in the mouth caused by multiple factors. Both periapical and marginal periodontitis are characterized by infection and inflammation around the affected teeth, suggesting that the theory of complex systems might describe the progression of EPL.
  • 1.4K
  • 27 Oct 2022
Topic Review
Image Derivatives
Image derivatives can be computed by using small convolution filters of size 2 x 2 or 3 x 3, such as the Laplacian, Sobel, Roberts and Prewitt operators. However, a larger mask will generally give a better approximation of the derivative and examples of such filters are Gaussian derivatives and Gabor filters. Sometimes high frequency noise needs to be removed and this can be incorporated in the filter so that the Gaussian kernel will act as a band pass filter. The use of Gabor filters in image processing has been motivated by some of its similarities to the perception in the human visual system. The pixel value is computed as a convolution where [math]\displaystyle{ \mathbf{d} }[/math] is the derivative kernel and [math]\displaystyle{ G }[/math] is the pixel values in a region of the image and [math]\displaystyle{ \ast }[/math] is the operator that performs the convolution.
  • 1.4K
  • 28 Oct 2022
Topic Review
Vision-Based Structural Vibration Tracking Using a Digital Camera
Computer-vision-based target tracking can be applied to structural vibration monitoring, but current target tracking methods suffer from noise in digital image processing. A new target-tracking method based on the sparse optical flow technique is introduced to improve the accuracy in tracking the target, especially when the target has a large displacement. The proposed method utilizes the ORB technique to maintain a variety of keypoints and combines the multi-level strategy with a sparse optical flow algorithm to search the keypoints with a large motion vector for tracking. Then, an outlier removal method based on Hamming distance and interquartile range (IQR) score is introduced to minimize the error. The proposed target tracking method is verified through a lab experiment---a three-story shear building structure subjected to various harmonic excitations. It is compared with existing sparse optical flow-based target tracking methods and target tracking methods based on three other types of techniques, i.e., feature matching, dense optical flow, and template matching. The results show that the performance of target tracking is greatly improved through the use of a multi-level strategy and the proposed outlier removal method. The proposed sparse optical flow-based target tracking method achieves the best accuracy compared to other existing target tracking methods.
  • 1.4K
  • 01 Dec 2022
Topic Review
Multi-Drug-Resistant Tuberculosis
Multi-drug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB medications (drugs), isoniazid and rifampin. Some forms of TB are also resistant to second-line medications, and are called extensively drug-resistant TB (XDR-TB). Tuberculosis is caused by infection with the bacteria Mycobacterium tuberculosis. Almost one in four people in the world are infected with TB bacteria. Only when the bacteria become active do people become ill with TB. Bacteria become active as a result of anything that can reduce the person's immunity, such as HIV, advancing age, diabetes or other immunocompromising illnesses. TB can usually be treated with a course of four standard, or first-line, anti-TB drugs (i.e., isoniazid, rifampin and any fluoroquinolone). However, beginning with the first antibiotic treatment for TB in 1943, some strains of the TB bacteria developed resistance to the standard drugs through genetic changes (see mechanisms.) Currently the majority of multidrug-resistant cases of TB are due to one strain of TB bacteria called the Beijing lineage. This process accelerates if incorrect or inadequate treatments are used, leading to the development and spread of multidrug-resistant TB (MDR-TB). Incorrect or inadequate treatment may be due to use of the wrong medications, use of only one medication (standard treatment is at least two drugs), not taking medication consistently or for the full treatment period (treatment is required for several months). Treatment of MDR-TB requires second-line drugs (i.e., fluoroquinolones, aminoglycosides, and others), which in general are less effective, more toxic and much more expensive than first-line drugs. Treatment schedules for MDR-TB involving fluoroquinolones and aminoglycosides can run for 2 years, compared to the 6 months of first-line drug treatment, and cost over US$100,000. If these second-line drugs are prescribed or taken incorrectly, further resistance can develop leading to XDR-TB. Resistant strains of TB are already present in the population, so MDR-TB can be directly transmitted from an infected person to an uninfected person. In this case a previously untreated person develops a new case of MDR-TB. This is known as primary MDR-TB, and is responsible for up to 75% of cases. Acquired MDR-TB develops when a person with a non-resistant strain of TB is treated inadequately, resulting in the development of antibiotic resistance in the TB bacteria infecting them. These people can in turn infect other people with MDR-TB. MDR-TB caused an estimated 600,000 new TB cases and 240,000 deaths in 2016 and MDR-TB accounts for 4.1% of all new TB cases and 19% of previously treated cases worldwide. Globally, most MDR-TB cases occur in South America, Southern Africa, India, China, and the former Soviet Union. Treatment of MDR-TB requires treatment with second-line drugs, usually four or more anti-TB drugs for a minimum of 6 months, and possibly extending for 18–24 months if rifampin resistance has been identified in the specific strain of TB with which the patient has been infected. Under ideal program conditions, MDR-TB cure rates can approach 70%.
  • 1.4K
  • 01 Dec 2022
Topic Review
Adaptive Façades
Adaptive building envelope systems can manage energy and mass transformation between indoor and outdoor environments, which contributes to the achievement of environmental benefits via reducing energy consumption and greenhouse gas emission while maintaining human comfort and well-being.
  • 1.4K
  • 14 Feb 2023
Topic Review
The Influencing Factors of Loess Carbon Sink
The relationship between the source and sink of atmospheric CO2 has always been a widely discussed issue in global climate change research. As one of the main overburdened parts of the earth, loess is one of the important driving factors for atmospheric CO2 consumption.
  • 1.4K
  • 13 Jan 2023
Topic Review
Reproductive Outcomes after the Treatment of Adenomyosis
Adenomyosis, also known as endometriosis genitalis interna, is a special form of endometriosis in which endometrial epithelial cells and stromal fibroblasts invade the uterine myometrium.
  • 1.4K
  • 18 Jan 2023
Topic Review
Dysregulated Immune Response after Burn Injury
Burn injury induces a complex inflammatory response, both locally and systemically, and is not yet completely unravelled and understood. In order to enable the development of accurate treatment options, it is of paramount importance to fully understand post-burn immunology. Persistent activity of complement, acute phase proteins and pro- and anti-inflammatory mediators, changes in lymphocyte activity, activation of the stress response and infiltration of immune cells have all been related to post-burn local and systemic pathology.
  • 1.4K
  • 08 Feb 2023
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