Oxide and chalcogenide nanoparticles have great potential for use in biomedicine, engineering, agriculture, environmental protection, and other research fields. The myco-synthesis of nanoparticles with fungal cultures, their metabolites, culture liquids, and mycelial and fruit body extracts is simple, cheap and environmentally friendly. The characteristics of nanoparticles, including their size, shape, homogeneity, stability, physical properties and biological activity, can be tuned by changing the myco-synthesis conditions.
Nanotechnology and nanomaterials science are rapidly developing fields, which contribute greatly to the development of modern technology and biomedicine. An important challenge is the development of simple, effective, and cheap methods of producing highly monodispersed, stable, and biocompatible nanoparticles (NPs) with the required chemical composition, shape, size, biological activity, and other properties. The recent increase in attention to environmental safety, natural resource exhaustibility, and human health safety has led to the increasing development of green NP-producing technologies by biosynthesis methods 
. Owing to its being environmentally benign and less resource-intensive than other methods, the synthesis of nontoxic and biocompatible NPs by using living organisms and a variety of biological materials derived from them is a promising alternative to physical and chemical fabrication methods.
The ability to biosynthesize NPs has been found in many organisms, including animals, plants, bacteria, fungi, actinomycetes, algae, lichens, and viruses 
. Among this diversity of biological objects used for green NP synthesis, a special place is occupied by fungi 
. Fungal cultures produce a wide range of proteins with high enzymatic activity, and due to that they can convert metals and other elements into less toxic forms. This includes the formation of NPs, which then accumulate in large quantities within the mycelium and/or extracellularly. As a result, micro- and macro-mycetes from different taxonomic groups can be successfully used to produce NPs and nanomaterials on an industrial scale. The applications of fungi in myco-nano-synthesis are also highly versatile. NPs with different characteristics can be obtained either by growing fungal cultures on media with precursors or by incubating these precursors with mycelial bio-mass, culture liquid filtrates, extracts from vegetative mycelium, fruiting bodies and other morpho-structures, and purified proteins and other metabolites isolated from fungi 
. In addition, the properties of biogenic NPs depend on medium composition, chemical composition and concentration of the precursor, incubation time, stirring rate, temperature, pH and other conditions. By varying these, the chemical composition, shape, size, homogeneity, stability, and biological activity of formed particles can be controlled 
2. Myco-Synthesis of Oxide Nanoparticles
To date, the ability to form elementary metal and metalloid NPs has been found in many fungal species. However, the number of elements that can be sources of mycogenic NPs is rather small and includes gold, silver, platinum, palladium, iron, copper, selenium, and tellurium 
. For oxides and salts, the range of chemical composition for mycogenic NPs is much wider, yet most of them remain very poorly studied. Among fungi-mediated oxide NPs, titanium, zinc, iron, and copper oxides have been studied to the greatest extent.
2.1. Myco-Synthesis of Copper Oxide Nanoparticles
Copper oxide NPs have attracted high attention because copper is one of the most important elements in modern technologies and is readily accessible 
. Copper oxide is widely used in catalysis, superconductors, thermoelectric and sensing materials, ceramics, gas sensors, and many other fields. Biomedical applications of these NPs include biosensors, cancer medicine, and antimicrobials 
. In recent years, the fungi-mediated synthesis of copper oxide NPs has become of interest (Table 1
Table 1. Myco-synthesis of copper oxide nanoparticles.