Video interview with Professor Brian Cantor from Department of Materials, University of Oxford, Oxford OX1 3PH, UK and BCAST, Brunel University, London, UB8 3PH, about his research on "New Materials and Manufacturing and Sustainability of Materials". Professor Cantor explains the importance of discovering new materials to the successful advancement and development of humankind in the past, at present and in the future. He goes on to explain how all our development to date has relied on new alloys, i.e. mixtures of starting materials, taking a main material and adding small amounts of 2 or 3 others to "tweak" up its properties. In the late 1970s and early 1980s, Professor Cantor started a revolution in making new material as multicomponent alloys, i.e. mixing several different starting material in large amounts. The first multicomponent material of this type is now known as the "Cantor alloy", and they are often called "high-entropy alloys". He explains why this approach had never been used before. More importantly, he explains how it means that there are literally trillions and trillions of materials that have never been investigated, so we can now go on to explore this vast new field of multicomponent high-entropy materials to get further developments for humankind: new energy conversion materials, new energy storage materials, stronger materials, better magnets, better conductors, more sustainable materials etc., etc. There are now thousands of scientists working on these new multicomponent, high-entropy and Cantor alloys, on multimillion dollar research programmes worldwide. ^[1][2]