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Epidemiology of Typhoid Fever
In 2000, typhoid fever caused an estimated 21.7 million illnesses and 217,000 deaths. It occurs most often in children and young adults between 5 and 19 years old. In 2013, it resulted in about 161,000 deaths – down from 181,000 in 1990. Infants, children, and adolescents in south-central and Southeast Asia experience the greatest burden of illness. Outbreaks of typhoid fever are also frequently reported from sub-Saharan Africa and countries in Southeast Asia. In the United States, about 400 cases occur each year, and 75% of these are acquired while traveling internationally. Historically, before the antibiotic era, the case fatality rate of typhoid fever was 10–20%. Today, with prompt treatment, it is less than 1%. However, about 3–5% of individuals who are infected develop a chronic infection in the gall bladder. Since S. e. subsp. enterica is human-restricted, these chronic carriers become the crucial reservoir, which can persist for decades for further spread of the disease, further complicating the identification and treatment of the disease. Lately, the study of S. e. subsp. enterica associated with a large outbreak and a carrier at the genome level provides new insights into the pathogenesis of the pathogen. In industrialized nations, water sanitation and food handling improvements have reduced the number of cases. Developing nations, such as those found in parts of Asia and Africa, have the highest rates of typhoid fever. These areas have a lack of access to clean water, proper sanitation systems, and proper health-care facilities. For these areas, such access to basic public-health needs is not in the near future.
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  • 24 Nov 2022
Topic Review
DubaiSat-1
DubaiSat-1 is a remote sensing Earth observation satellite built by the Emirates Institution for Advanced Science and Technology (EIAST) under an agreement with Satrec Initiative, a satellite manufacturing company in South Korea . DubaiSat-1 was launched on 29 July 2009 into a 680 km altitude sun-synchronous polar orbit from the Baikonur launch site in Kazakhstan, along with several other satellites on board the Dnepr launch vehicle.
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  • 24 Nov 2022
Topic Review
Effort Incontinence
Urinary incontinence (UI), also known as involuntary urination, is any uncontrolled leakage of urine. It is a common and distressing problem, which may have a large impact on quality of life. It has been identified as an important issue in geriatric health care. The term enuresis is often used to refer to urinary incontinence primarily in children, such as nocturnal enuresis (bed wetting). UI is an example of a stigmatized medical condition, which creates barriers to successful management and makes the problem worse. People may be too embarrassed to seek medical help, and attempt to self-manage the symptom in secrecy from others. Pelvic surgery, pregnancy, childbirth, and menopause are major risk factors. Urinary incontinence is often a result of an underlying medical condition but is under-reported to medical practitioners. There are four main types of incontinence: Treatments include pelvic floor muscle training, bladder training, surgery, and electrical stimulation. Behavioral therapy generally works better than medication for stress and urge incontinence. The benefit of medications is small and long term safety is unclear. Urinary incontinence is more common in older women.
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  • 24 Nov 2022
Topic Review
Convective Boundary Layer
The Convective Boundary layer (CBL), also known as the daytime Planetary boundary layer, is the part of the atmosphere most directly affected by solar heating of the earth's surface. This layer extends from the earth surface to a capping inversion that typically locates at a height of 1–2 km by midafternoon over land. Below the capping inversion (10-60% of CBL depth, also called entrainment zone in the daytime), CBL is divided into two sub-layers: mixed layer (35-80% of CBL depth) and surface layer (5-10% of CBL depth). The mixed layer, the major part of CBL, has a nearly constant distribution of quantities such as potential temperature, wind speed, moisture and pollutant concentration because of strong buoyancy generated convective turbulent mixing. Parameterization of turbulent transport is used to simulate the vertical profiles and temporal variation of quantities of interest, because of the randomness and the unknown physics of turbulence. However, turbulence in the mixed layer is not completely random, but is often organized into identifiable structures such as thermals and plumes in the CBL. Simulation of these large eddies is quite different from simulation of smaller eddies generated by local shears in the surface layer. Non-local property of the large eddies should be accounted for in the parameterization.
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  • 24 Nov 2022
Topic Review
List of Intel Core I7 Microprocessors
The following is a list of Intel Core i7 brand microprocessors. Introduced in 2008, the Core i7 line of microprocessors are intended to be used by high-end users.
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  • 24 Nov 2022
Topic Review
1968 Burma Cyclone
The 1968 Burma cyclone was regarded as the worst to strike the country during the 20th century before it was surpassed by another unnamed cyclone in 2004 and further, Cyclone Nargis in 2008, respectively. The first tropical cyclone of the 1968 North Indian Ocean cyclone season, it started as a depression on May 7 on the northern Andaman Sea. With low wind shear and warm sea surface temperatures, the storm intensified in the waters near Burma before heading northwestwards. It then started to rapidly intensify, with an eye becoming apparent on satellite imagery on May 9. Also that day, it reached its peak intensity, with 3-minute maximum sustained winds of 220 km/h (140 mph) by the Indian Meteorological Department, which is equivalent to a super cyclonic storm; however, the agency treated the system as a severe cyclonic storm. Little to no changes happened on the cyclone as it turned northeastwards, making landfall near Akyab (now Sittwe) between 18:00 and 21:00 UTC on that day. Land interaction rapidly weakened the storm, dissipating on May 10 as an area of low-pressure in south Chin State. The predecessor to the cyclone caused light to moderate downpour to the Andaman Islands; however, no deaths were reported. Winds reported from the cyclone inland Burma reached an estimate of 60–100 mph, altogether with heavy rainfall and large storm surges. The former flooded the crops, submerging them in floodwaters in the process while the latter washed out villages near the path of the storm. Schools and hospitals throughout Akyab were destroyed by high winds and large waves, while the port suffered major damages. The town was almost destroyed due to the storm. In addition, some ships in the said harbor, including the Greek freighter Geros Michalos were reportedly sunk in the Bay of Bengal. Houses were destroyed during the storm and many livestock died, mainly due to drowning. The death toll from the cyclone was finalized on May 1968 at 1,307 individuals, while 2,000 more were reportedly missing. The property damages were estimated at K15 million kyat ($3.248 million United States dollar ). After the cyclone, the Government of Burma started to release aid to the victims, altogether with food supplies and cotton blankets. The Red Cross Society of the country donated cases of medicines to the country, while the United States Government released over 25,000 blankets to be transferred to the area. In addition, many countries and organizations including the UNICEF contributed over $121,291 (1968 USD) to Myanmar, following the disaster.
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Topic Review
Confined Environment Psychology
Confined environment psychology is a refined subcategory of environmental psychology. There can be severe neurological impacts upon remaining in a confined environment over a prolonged period of time. Confined environment psychology can come in different forms, including; by location and lack of or limited human interaction. The broad subcategory also includes the effects of social isolation on animals. Behavioural and Neurological impacts of confined environments Solitary confinement and isolation can have severe psychological effects and is heavily dependent on the extent of isolation, particularly for prisoners. A study conducted by Stuart Grassian stated some of the behavioural effects of solitary confinement and isolation include agitative behaviour, hallucinations and restlessness. Solitary confinement and isolation can disrupt the function of neurotransmitter systems, which result in unusual behaviour. Mice experience similar behaviour to humans, including agitation and aggression, fear and hypersensitivity to unfamiliar objects that are viewed as a threat. Neurologically, chronic social isolation for mice activates a neuropeptide found in the central nervous system known as tachykinin. Tachykinin (also known as the TACC2 gene for mice) is produced in the amygdala and hypothalamus of a mouse's brain. These regions of the mouse brain directly control the behaviour of mice emotionally and socially. Suppressing certain neurochemicals can have an adverse effect on the behaviour of mice.
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  • 24 Nov 2022
Topic Review
Evolution of the Domesticated Cat
The domestic cat originated from Near-Eastern and Egyptian populations of the African wildcat, Felis sylvestris lybica. The family Felidae, to which all living feline species belong, arose about ten to eleven million years ago. This family is divided into eight major phylogenetic lineages. The domestic cat is a member of the Felis lineage. A number of investigations have shown that all domestic varieties of cats come from a single species of the Felis lineage, Felis catus. Variations of this lineage are found all over the world and up until recently scientists have had a hard time pinning down exactly which region gave rise to modern domestic cat breeds. Scientists believed that it was not just one incident that led to the domesticated cat but multiple, independent incidents at different places that led to these breeds. More complications arose from the fact that the wildcat population as a whole is very widespread and very similar to one another. These variations of wild cat can and will interbreed freely with one another when in close contact, further blurring the lines between taxa. Recent DNA studies, advancement in genetic technologies, and a better understanding of DNA and genetics as a whole has helped make discoveries in the evolutionary history of the domestic cat.
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  • 25 Nov 2022
Topic Review
Office Online
Office Online (known before 2014 as Office Web Apps and as of July 2019 as Office) is an online office suite offered by Microsoft, which allows users to create and edit files using lightweight Microsoft Office web apps: Word, Excel, PowerPoint and OneNote. The offering also includes Outlook.com, People, Calendar and OneDrive, all of which are accessible from a unified app switcher. Users can install the on-premises version of this service, called Office Online Server, in private clouds in conjunction with SharePoint, Microsoft Exchange Server and Microsoft Lync Server.
  • 2.2K
  • 25 Nov 2022
Topic Review
Household
A household consists of one or several persons who live in the same dwelling and share meals. It may also consist of a single family or another group of people. The household is the basic unit of analysis in many social, microeconomic and government models, and is important to economics and inheritance. Household models include families, blended families, shared housing, group homes, boarding houses, houses of multiple occupancy (UK), and single room occupancy (US). In feudal societies, the royal household and medieval households of the wealthy included servants and other retainers.
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  • 24 Nov 2022
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