Summary

On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Caused by SARS-CoV-2, COVID-19 continues nearly 18 months later to present significant challenges to health systems and public health in both hemispheres, as well as the economies of every country. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed many hospitals and clinics and continue to do so in many countries. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This entry collection aims to gather diverse fields about COVID-19, including in epidemiology, public health, medicine, genetics, systems biology, informatics, data science, engineering, sociology, anthropology, nursing, environmental studies, statistics, and psychology.

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Entries
Topic Review
Biosensing Technologies for SARS-CoV-2
COVID-19 viral disease is officially global pandemic, currently accounting for the highest number of deaths worldwide. Special screening is extremely important as an effective way to monitor and manage the pandemic before reaching herb immunity through effective vaccination against SARS-CoV-2. A rapid population control task for COVID-19 has been documented using innovative methods in biosensor development. Biosensors are selected as promising detection devices with enormous potential as point-of-care (POC) tools to confirm the SARS-CoV-2 infection. Timely testing also helps to effectively allocate medical resources and save time for frontline medical staff. Hence, simple, rapid, cost-effective, and accessible detection techniques as POC diagnostics for large-scale screening and field testing of SARS-CoV-2 infection is important and should urgently be expedited to control the rapid and contagious spread of COVID-19. 
  • 626
  • 03 Jun 2021
Topic Review Peer Reviewed
Pandemic Prevention: Lessons from COVID-19
Coronavirus disease 2019 (COVID-19) is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which appeared in late 2019, generating a pandemic crisis with high numbers of COVID-19-related infected individuals and deaths in manifold countries worldwide. Lessons learned from COVID-19 can be used to prevent pandemic threats by designing strategies to support different policy responses, not limited to the health system, directed to reduce the risks of the emergence of novel viral agents, the diffusion of infectious diseases and negative impact in society.
  • 884
  • 18 Apr 2022
Topic Review
In Vitro Lung Models
In vitro lung models are used to faithfully model basic human pathology and the complexity and diversity of human respiratory tissues and to study emerging viral respiratory pathogens and diseases. These models include conventional cell lines, primary human airway epithelial cell (hAEC) cultures, lung organoids, lung-on-a-chip technology, ex vivo lung perfusion (EVLP) models and human lung tissue explants.
  • 1.7K
  • 23 Jun 2021
Topic Review
Post-COVID Syndrome
Post-COVID syndrome is increasingly recognized as a new clinical entity in the context of SARS-CoV-2 infection.
  • 572
  • 23 Jun 2021
Topic Review
Routine Laboratory Biomarkers Detecting COVID-19
No routine laboratory biomarkers perform well enough in diagnosing COVID-19 in isolation for them to be used as a standalone.
  • 456
  • 26 May 2021
Topic Review
Post-COVID-19 Symptoms and Dental Management
The available data regarding the short and long-term consequences of COVID-19 is still insufficient. This entry aims to provide information on the prolonged COVID-19 symptoms in recovered patients and their implications during dental management. 
  • 3.4K
  • 27 May 2021
Topic Review
COVID-19 and Education
COVID-19 has produced a transformation in society that has, in turn, influenced the field of education. The purpose of this study was to analyze the influence of COVID-19 on education using the Web of Science database. A methodology based on bibliometrics was used. Specifically, a scientific mapping of the literature was carried out, as well as a co-word analysis on the state of the question. The analysis included 940 publications. The results show that the institution with the highest volume of production in this field is the University of London. Among the journals, the Journal of Chemical Education stands out. Furthermore, in the analysis of the structural and thematic development of co-words, a high percentage of keyword matching was observed. In 2020, the motor themes were mental-health, organic-chemistry, general-public, first-year-undergraduate, and upper-division-undergraduate, while in 2021, they were autism-spectrum-disorder, adoption, internet, and intervention. It can be concluded that investigation into COVID-19 in the educational field is in its initial process. 
  • 523
  • 21 May 2021
Topic Review
Probiotics and Photobiomodulation
Multiple interconditioning between photobiomodulation (PBM), probiotics, and the human microbiota, their effects on the human body, and their implications for the management of viral infectious diseases is essential. Coupled complex PBM and probiotic interventions can control the microbiome, improve the activity of the immune system, and save the lives of people with immune imbalances. 
  • 744
  • 20 May 2021
Topic Review
Lipid-Based Nanoparticles
COVID-19 vaccines have been developed with unprecedented speed which would not have been possible without decades of fundamental research on delivery nanotechnology. Lipid-based nanoparticles have played a pivotal role in the successes of COVID-19 vaccines and many other nanomedicines, such as Doxil® and Onpattro®, and have therefore been considered as the frontrunner in nanoscale drug delivery systems. In this review, we aim to highlight the progress in the development of these lipid nanoparticles for various applications, ranging from cancer nanomedicines to COVID-19 vaccines. The lipid-based nanoparticles discussed in this review are liposomes, niosomes, transfersomes, solid lipid nanoparticles, and nanostructured lipid carriers. We particularly focus on the innovations that have obtained regulatory approval or that are in clinical trials. We also discuss the physicochemical properties required for specific applications, highlight the differences in requirements for the delivery of different cargos, and introduce current challenges that need further development. This review serves as a useful guideline for designing new lipid nanoparticles for both preventative and therapeutic vaccines including immunotherapies.
  • 4.9K
  • 19 May 2021
Topic Review
Convalescent Plasma Transfusion for COVID‐19
More than one year into the novel coronavirus disease 2019 (COVID-19) pandemic, healthcare systems across the world continue to be overwhelmed with soaring daily cases. The treatment spectrum primarily includes ventilation support augmented with repurposed drugs and/or convalescent plasma transfusion (CPT) from recovered COVID-19 patients. CPT is a promising COVID-19 therapeutic option that merits internationally coordinated RCTs to achieve a scientific risk-benefit consensus. 
  • 352
  • 24 May 2021
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