Summary

On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Caused by SARS-CoV-2, COVID-19 continues nearly 18 months later to present significant challenges to health systems and public health in both hemispheres, as well as the economies of every country. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed many hospitals and clinics and continue to do so in many countries. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This entry collection aims to gather diverse fields about COVID-19, including in epidemiology, public health, medicine, genetics, systems biology, informatics, data science, engineering, sociology, anthropology, nursing, environmental studies, statistics, and psychology.

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Entries
Topic Review
Artificial Intelligence in Adaptive and Intelligent Educational System
There has been much discussion among academics on how pupils may be taught online while yet maintaining a high degree of learning efficiency, in part because of the worldwide COVID-19 pandemic in the previous two years. Students may have trouble focusing due to a lack of teacher–student interaction, yet online learning has some advantages that are unavailable in traditional classrooms. The architecture of online courses for students is integrated into a system called the Adaptive and Intelligent Education System (AIES). In AIESs, reinforcement learning is often used in conjunction with the development of teaching strategies, and this reinforcement-learning-based system is known as RLATES.
  • 574
  • 21 Sep 2022
Topic Review
Impact of Strategy Change on Business Process Management
In the pursuit of economic survival in the current competitive conditions with the aim of long-term prosperity and sustainability in the market, many companies today approach significant strategic changes in the management of their business. The design of a systematic procedure for implementing strategy changes into internal business processes for a project-oriented production type of organization is of importance. 
  • 1.7K
  • 14 Sep 2022
Topic Review
Nanoscale Technologies in the Fight against COVID-19
The last few years have increasingly emphasized the need to develop, through nanoscale technologies, new active antiviral products useful for infection prevention and control. At the same time, advanced computational approaches have found themselves fundamental in the repurposing of active therapeutics or for reducing the very long developing phases of new drugs discovery, which represents a real limitation, especially in the case of pandemics.
  • 451
  • 13 Sep 2022
Topic Review
Urban Community Resilience Amidst the Spreading of COVID-19
Based on 90% of all reported COVID-19 in the world, urban areas become the pandemic’s epicenter due to population size and high-level global connectivity, rather than rural areas. Urban research related to pandemics focuses on marginal groups who have difficulty accessing health facilities, particularly in informal settlements. Amid a pandemic, insufficient isolation for COVID-19 patients may be related to the rapid increase of COVID-19 cases. Lockdown has worsened economic conditions for informal workers in urban areas, the lack of labor market opportunities, livelihood advancement, and occupational mobility for informal workers make it difficult to survive in the city. Loss of income due to the lockdown has made marginal communities in urban areas more vulnerable because they have to bear the changing needs of life during the pandemic.
  • 442
  • 16 Sep 2022
Topic Review
COVID-19 and Gestational Diabetes
Gestational diabetes mellitus (GDM) is defined as glucose intolerance first identified during pregnancy and usually resolving after birth. Since the beginning of the COVID-19 pandemic, there has been a growing interest in the association between GDM and COVID-19.
  • 360
  • 13 Sep 2022
Topic Review
COVID-19 Vaccination Policy Resistance
The pandemic of the infectious disease COVID-19 caused by the SARS-CoV-2 virus drastically changed the world and led to the so-called “new normality”. It was reflected in reduced social and physical contacts, considerable changes in business operations, loss of employment, mental health impairment, endangerment of material existence, etc. While the situation seemed hopeless at the outset of the pandemic, generating great fear and anxiety, people became mentally accustomed to the new situation over time. The situation was significantly improved upon with the discovery of vaccines, but the emergence of vaccines was accompanied by new dilemmas, social divisions and conflicts. The point of contention between experts and citizens was the vaccine’s safety. Contradictory information started spreading through social networks, creating huge animosity among citizens.
  • 538
  • 15 Sep 2022
Topic Review
Visceral Leishmaniasis in COVID-19
Leishmaniasis is a zoonosis that may present general symptoms, including fever, malaise, and arthralgia, rendering it indistinguishable from COVID-19.
  • 483
  • 09 Sep 2022
Topic Review
CRISPR-Based Assays for Effective Detection of SARS-CoV-2
Coronavirus disease (COVID-19) caused by the SARS-CoV-2 has been an outbreak since late 2019 up to now. This pandemic causes rapid development in molecular detection technologies to diagnose viral infection for epidemic prevention. In addition to antigen test kit (ATK) and polymerase chain reaction (PCR), CRISPR-based assays for detection of SARS-CoV-2 have gained attention because it has a simple setup but still maintain high specificity and sensitivity.
  • 345
  • 09 Sep 2022
Topic Review
Dipeptidyl Peptidase-4 (DPP4) on COVID-19 Physiopathology
DPP4/CD26 is a single-pass transmembrane protein with multiple functions on glycemic control, cell migration and proliferation, and the immune system, among others. It has acquired an especial relevance due to the possibility to act as a receptor or co-receptor for SARS-CoV-2, as it has been already demonstrated for other coronaviruses. The broad spectrum of functions regulated by DPP4 is performed both as a protease enzyme, as well as an interacting partner of other molecules on the cell surface. 
  • 403
  • 07 Sep 2022
Topic Review
Obesity, Body Composition, and Nutrition in COVID-19 Pandemia
The coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, infecting nearly 500 million people, with more than 6 million deaths recorded globally. Obesity leads people to be more vulnerable, developing worse outcomes that can require hospitalization in intensive care units (ICU). Most studies showed that not only body fat quantity but also its distribution seems to play a crucial role in COVID-19 severity. Compared to the body mass index (BMI), visceral adipose tissue and intrathoracic fat are better predictors of COVID-19 severity and indicate the need for hospitalization in ICU and invasive mechanical ventilation. High volumes of epicardial adipose tissue and its thickness can cause an infection located in the myocardial tissue, thereby enhancing severe COVID-related myocardial damage with impairments in coronary flow reserve and thromboembolism. 
  • 421
  • 07 Sep 2022
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