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Topic Review
Greenfield Investment and Green Economic Growth
The intensification of countries’ growth causes the depletion of natural resources, biodiversity degradation, ecological imbalances, damage, and disasters. The aggravation of ecological issues requires the development of mechanisms for simultaneous achievement of economic, social, and ecological goals. The energy sector is the core direction of economic decarbonization. Therefore, green economic growth requires economic development due to the extension of innovative technologies for renewable energies and relevant investment for that. The concept of “green economic growth” is linked to the paradigm of sustainable development and reflects economic growth considering the rational use of natural capital, prevents and reduces pollution and developed opportunities to improve social well-being due to providing carbon-neutral economy. The concept of “greenfield investment” is wider and complex definitions, the scholars define it as the investment on environmental, social and governance projects which aims to achieve sustainable development goals in long-term.
  • 184
  • 05 Mar 2024
Topic Review
Opportunities for Biodiversity Conservation via Urban Ecosystem Regeneration
Conservation traditionally focuses on at-risk species and relatively intact ecosystems. As the human population and our global impact have risen, many more species and ecosystems are at risk and fewer intact ecosystems remain, with urbanization being a major contributing factor. Cities and their inhabitants are here to stay, and the prevalence of urbanization, often in the vicinity of areas of high conservation value, requires reconsideration of the conservation value of urban ecosystems and urban green spaces.
  • 227
  • 05 Mar 2024
Topic Review
DL-SLICER
A novel artificial intelligence (AI)-driven city classification method which provides a homogeneous and unbiased result, employing visual and publicly accessible data focusing on factual circumstances and complex visual causalities. It offers a new perspective in the research domain by developing a deep learning (DL) tool that analyzes visual information from city satellite image patches.
  • 176
  • 05 Mar 2024
Topic Review
Etiopathogenic Factors for Obesity
Obesity is an abnormal or excessive accumulation of fat that represents a health risk, and it is characterized by reaching a body mass index (BMI) equal to or greater than 30 kg/m2. Obesity is a chronic disease of multifactorial etiology that involves an energy imbalance, genetic and epigenetic factors, alterations in glucose and lipid metabolism, disorders of adipose tissue functioning, neuroendocrine dysregulation, and alterations in the intestinal microbiota, among others.
  • 190
  • 05 Mar 2024
Topic Review
Tunicamycin in the Therapeutic Implication of Cancers
Tunicamycin (TM) is one of the potent nucleoside antibiotics and an inhibitor of aberrant glycosylation in various cancer cells, including breast cancer, gastric cancer, and pancreatic cancer, parallel with the inhibition of cancer cell growth and progression of tumors. Like chemotherapies such as doxorubicin (DOX), 5′fluorouracil, etoposide, and cisplatin, TM induces the unfolded protein response (UPR) by blocking aberrant glycosylation. Consequently, stress is induced in the endoplasmic reticulum (ER) that promotes apoptosis.
  • 94
  • 05 Mar 2024
Topic Review
Ferroptosis in Cardiovascular Disease and Cardiomyopathies
In the realm of cardiovascular diseases, it significantly contributes to cardiomyopathies, including dilated cardiomyopathy, hypertrophic cardiomyopathy, and restrictive cardiomyopathy. Ferroptosis involves intricate interactions within cellular iron metabolism, lipid peroxidation, and the balance between polyunsaturated and monounsaturated fatty acids. Molecularly, factors like p53 and nuclear factor (erythroid-derived 2)-like 2 (Nrf2) impact cellular susceptibility to ferroptosis under oxidative stress. Understanding ferroptosis is vital in cardiomyopathies, where cardiac myocytes heavily depend on aerobic respiration, with iron playing a pivotal role. Dysregulation of the antioxidant enzyme glutathione peroxidase (GPX4) is linked to cardiomyopathies, emphasizing its significance. Ferroptosis’s role in myocardial ischemia-reperfusion injury, exacerbated in diabetes, underscores its relevance in cardiovascular conditions.
  • 339
  • 05 Mar 2024
Topic Review
GLP-1RA-Associated Side Effects and Potential Concerns
Amidst the obesity and type II diabetes mellitus (T2DM) epidemics, glucagon-like peptide-1 receptor agonists (GLP-1RAs) stand out as a promising therapeutic ally, achieving notable success in glycemic control and weight management. While GLP-1RAs’ positive clinical outcomes are commendable, they introduce significant gastrointestinal (GI) challenges, emphasizing the pivotal role of gastroenterologists in understanding and managing these implications. Physicians should be vigilant of potential complications if endoscopy is indicated and considered.
  • 192
  • 05 Mar 2024
Topic Review
Incorporation of Inorganic Antimicrobial Agents into Nanofibers
Nanofibrous materials represent a very promising form of advanced carrier systems that can be used industrially, especially in regenerative medicine as highly functional bandages, or advanced wound dressings. By incorporation of antimicrobial additives directly into the structure of the nanofiber carrier, the functionality of the layer is upgraded, depending on the final requirement—bactericidal, bacteriostatic, antiseptic, or a generally antimicrobial effect. Such highly functional nanofibrous layers can be prepared mostly by electrospinning technology from both synthetic and natural polymers. The presence of a natural polymer in the composition is very advantageous. Especially in medical applications where, due to the presence of the material close to the human body, the healing process is more efficient and without the occurrence of an unwanted inflammatory response.
  • 114
  • 05 Mar 2024
Topic Review
Chitosan Application in Grapevine for Abiotic Stress/Disease Management
Chitosan is a biopolymer with various favorable properties (biotic/abiotic stress mitigation, qualitative improvement, bio-fertilizer, bio-stimulant and postharvest management) to meet multiple agricultural objectives. Grapevine is an important crop and has an enormous impact on the world’s economy due to its derived products, notably the different wine styles. In viticulture, chitosan application made significant developments towards higher contents of beneficial metabolites in grape berries as well as stress and postharvest management.
  • 119
  • 05 Mar 2024
Topic Review
Medicinal Uses of Acacia seyal
Acacia seyal is an important source of gum Arabic. The availability, traditional, medicinal, pharmaceutical, nutritional, and cosmetic applications of gum acacia have pronounced its high economic value and attracted global attention.
  • 360
  • 05 Mar 2024
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