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Topic Review
Four Strategies to Prevent Metabolic Syndrom
Metabolic syndrome (MetS) is a clustering of biochemical and physical conditions associated with an increased risk for developing type 2 diabetes (T2D) and cardiovascular diseases. Excess abdominal fat is most closely associated with metabolic risk factors and is most likely the initiating factor of risk factor clustering in MetS. These risk factors, namely, impaired blood glucose, dyslipidaemia, and raised blood pressure, are symptoms of metabolic chaos inside the body.
  • 471
  • 29 Mar 2022
Topic Review
Intellectual Disability and Physical Activity Participation Perceived Barriers
Individuals with intellectual disability (ID) tend to have a sedentary lifestyle, with low physical fitness and an increased risk of chronic diseases. One reason for the prevalence of a sedentary lifestyle is the existence of barriers to participation in physical activity (PA).
  • 624
  • 29 Mar 2022
Topic Review
Weight Loss
Overweight and obesity are related pathological conditions with a significant impact at the cardiovascular, metabolic, musculoskeletal, and oncological levels, representing a significant global public health problem. The traditionally proposed therapeutic approaches act at the nutritional, psychological, lifestyle (abolishing sedentary lifestyle and promoting physical exercise), and pharmacological levels, in combination with the consumption of food supplements.
  • 721
  • 29 Mar 2022
Topic Review
High-Intensity Interval Training
High-Intensity Interval Training (HIIT) could have effects on inflammatory biomarkers, based on the investigation conducted of an anti-inflammatory nature, provided that its characteristics are able to trigger the necessary impact to do so.
  • 478
  • 29 Mar 2022
Topic Review
Motor Fitness and Flexibility Tests in Older Adults
Strong evidence indicated that (i) slower gait speed predicts falls and institutionalization/hospitalization in adults over 60 years old, cognitive decline/impairment over 55 years old, mobility disability over 50 years old, disability in instrumental activities of daily living (IADL) over 54 years old, cardiovascular disease risk over 45 years old, and all-cause mortality over 35 years old; (ii) impaired balance predicts falls and disability in IADL/mobility disability in adults over 40 years old and all-cause mortality over 53 years old; (iii) worse timed up&go test (TUG) predicts falls and fear of falling over 40 years old. Evidence supports that slower gait speed, impaired balance, and worse TUG performance are significantly associated with an increased risk of adverse health outcomes in adults. 
  • 637
  • 29 Mar 2022
Topic Review
Diabetic Foot with Exercise Therapy
Diabetic foot (DF) is a long-term diabetes complication that can increase morbidity and mortality in addition to affecting mobility and the overall well-being of patients. In particular, the DF has a complex multifactorial pathogenesis that makes it difficult to prevent and treat. In this sense, it is well known that the prevention and treatment of DF disease requires a multidisciplinary approach. Physical activity has always been considered a potential pillar in the prevention of DFD. More recently, it has been reported, that physical activity can contribute in the wound healing phase. Unfortunately, to date, there is no clear and definitive evidence on the role that protocols of physical activity can play in the treatment of patients at risk or with DFD. In order to pursue this objective, it is important to standardize exercise training protocols for the prevention or treatment of these patients. Moreover, it is now possible to organize innovative methods of conducting, monitoring and analysing physical activity performed by patients, even remotely.
  • 494
  • 29 Mar 2022
Topic Review
Potential Nutraceuticals in Alzheimer’s Disease
Alzheimer’s disease (AD) incidence is increasing worldwide at an alarming rate. Considering this increase, prevention efforts, stemming from scientific research, health education, and public policies, are critical. Clinical studies evidenced that healthy lifestyles along with natural multitarget and disease-modifying agents have a preventative impact on AD or mitigate symptoms in diagnosed patients.
  • 773
  • 29 Mar 2022
Topic Review
Sarcopenia and Sarcopenic Obesity
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related sarcopenia is characterized by decreased muscular strength, decreased muscle quantity, quality, and decreased functional performance. Sarcopenic obesity (SO) is a condition that combines sarcopenia and obesity and has a substantial influence on the older adults’ health.
  • 517
  • 29 Mar 2022
Topic Review
SiRNA and Pancreatic Cancer Therapy
Pancreatic cancer (PC) is one of the leading causes of death and is the fourth most malignant tumor in men. The epigenetic and genetic alterations appear to be responsible for development of PC. Small interfering RNA (siRNA) is a powerful genetic tool that can bind to its target and reduces expression level of a specific gene. The various critical genes involved in PC progression can be effectively targeted using diverse siRNAs. 
  • 439
  • 29 Mar 2022
Topic Review
Protein Intake in Pre-Dialysis Chronic Kidney Disease Patients
In chronic degenerative diseases related to nitrogen metabolism and excretion, such as chronic kidney disease (CKD), the optimization of the amount of protein ingested in the diet is especially relevant. The occurrence of metabolic disorders and the nature of the amino acid mixture resulting from protein digestion, the general state of the patient and the severity of the CKD implies that proper protein intake should be carefully considered.
  • 944
  • 29 Mar 2022
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