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Topic Review
Interventions for Early-Stage Pericoronitis
Evidence of low methodological quality and high clinical diversity showed that there are still uncertainties to estimate the effect of the different interventions for pericoronitis. It is important to note that pericoronitis is an inflammation of the tissues around the crown. Until now, initial pericoronitis should be resolved with local irrigation and gently debridement. Antibiotics should be specially reserved for severe cases when systemic dissemination are present. 
  • 467
  • 21 Feb 2022
Topic Review
Risks of Mobile Phones for Children and Teenagers
Mobile phones have become ubiquitous in modern society, with many children and teenagers using them on a daily basis. However, there are growing concerns about the potential health risks associated with mobile phone use, particularly among young people. The risks of mobile phones for children and teenagers, including the potential for radiation exposure, impact on mental health, and effects on sleep were described. The strategies for reducing these risks and promoting safe mobile phone use among young people, as well as the countries and governments that are taking action to address this issue were discussed.
  • 464
  • 22 May 2023
Topic Review
Physiotherapy Management in Endometriosis
Endometriosis is a disease whose underlying cause is the growth of the endometrium outside the uterine cavity. The disease is characterised by unpleasant pain in the pelvic region, irrespective of the phase of the woman’s cycle. Physiotherapy in its various forms can be an excellent complement to the gynaecological treatment of endometriosis, by virtue of reducing inflammation, alleviating pain and thus significantly improving women’s quality of life.
  • 465
  • 08 Dec 2022
Topic Review
Diagnosis Application of MINI and BERT
Researchers propose a mental health diagnosis application for Arabic-speaking patients using both The MINI-International Neuropsychiatric Interview (MINI) and the supervised machine learning BERT model to equip the psychiatry department of the Military Hospital of Instruction of Tunis with a rapid and intelligent tool handling the high number of patients treated every day.
  • 465
  • 29 Jan 2022
Topic Review
Mediterranean Diet Adherence before/after BS
To the best of current knowledge, very few studies have been performed with regards to the effects of a Mediterranean diet on bariatric surgery outcomes.
  • 465
  • 08 Feb 2022
Topic Review
Selenium Status in Patients with Chronic Liver Disease
The potential role of selenium in preventing chronic liver diseases remains controversial. Both body selenium status and selenium intake were negatively associated with hepatitis, cirrhosis, and liver cancer. However, the associations for fatty liver diseases were conflicting and need to be established in prospective trials.
  • 464
  • 11 Mar 2022
Topic Review
Quercetin in Coronavirus Infections
The COVID-19 outbreak seems to be the most dangerous challenge of the third millennium due to its highly contagious nature. Amongst natural molecules for COVID-19 treatment, the flavonoid molecule quercetin (QR) is currently considered one of the most promising. QR is an active agent against SARS and MERS due to its antimicrobial, antiviral, anti-inflammatory, antioxidant, and some other beneficial effects. QR may hold therapeutic potential against SARS-CoV-2 due to its inhibitory effects on several stages of the viral life cycle.
  • 465
  • 06 Sep 2022
Topic Review
Microfluidic Platform for COVID-19
Spread of coronavirus disease 2019 (COVID-19) has significantly impacted the public health and economic sectors. It is urgently necessary to develop rapid, convenient, and cost-effective point-of-care testing (POCT) technologies for the early diagnosis and control of the plague’s transmission. Developing POCT methods and related devices is critical for achieving point-of-care diagnosis. The POCT devices based on microfluidic technology on the market, including paper-based microfluidic, centrifugal microfluidic, optical fluid, and digital microfluidic platforms.
  • 464
  • 16 Feb 2023
Topic Review
Antibiotics Prescribing during COVID-19 Pandemic
It is axiomatic that hospital admissions increase risks of healthcare-associated infections (HCAIs), leading to a noticeable increase in antibiotic consumption. A recent study conducted on ICU patients in 88 countries highlighted that 70% of hospitalized patients receive at least one antibiotic during acute admission; of this cohort 54% developed a secondary bacterial infection that necessitated antibiotic therapy. In patients with severe disease, the WHO recommends the provision of antimicrobial therapy to prevent furthers infection complications, leading to severe acute respiratory distress syndrome (ARDS) and multi-organ failure.
  • 463
  • 27 Aug 2021
Topic Review
SARS-CoV-2 Spike Protein-Induced Dysfunction of the NRP-1/VEGF-A Complex
Long coronavirus disease-19 (COVID-19) is a newly discovered syndrome characterized by multiple organ manifestations that persist for weeks to months, following the recovery from acute disease. Occasionally, neurological and cardiovascular side effects mimicking long COVID-19 have been reported in recipients of COVID-19 vaccines. Hypothetically, the clinical similarity could be due to a shared pathogenic role of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike (S) protein produced by the virus or used for immunization. The S protein can bind to neuropilin (NRP)-1, which normally functions as a coreceptor for the vascular endothelial growth factor (VEGF)-A. By antagonizing the docking of VEGF-A to NRP-1, the S protein could disrupt physiological pathways involved in angiogenesis and nociception. One consequence could be the increase in unbound forms of VEGF-A that could bind to other receptors. SARS-CoV-2-infected individuals may exhibit increased plasma levels of VEGF-A during both acute illness and convalescence, which could be responsible for diffuse microvascular and neurological damage.
  • 463
  • 20 Jan 2023
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