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Topic Review
Biosensors and Microfluidic Biosensors
Biosensors are ubiquitous in a variety of disciplines, such as biochemical, electrochemical, agricultural, and biomedical areas. They can integrate various point-of-care applications, such as in the food, healthcare, environmental monitoring, water quality, forensics, drug development, and biological domains. Multiple strategies have been employed to develop and fabricate miniaturized biosensors, including design, optimization, characterization, and testing. In view of their interactions with high-affinity biomolecules, they find application in the sensitive detection of analytes, even in small sample volumes. Among the many developed techniques, microfluidics have been widely explored; these use fluid mechanics to operate miniaturized biosensors. The currently used commercial devices are bulky, slow in operation, expensive, and require human intervention; thus, it is difficult to automate, integrate, and miniaturize the existing conventional devices for multi-faceted applications. Microfluidic biosensors have the advantages of mobility, operational transparency, controllability, and stability with a small reaction volume for sensing. 
  • 552
  • 05 Aug 2022
Topic Review
Prevention and Clinical Management of Major Depressive Disorder
Major Depressive Disorder (MDD) is a growing disabling condition affecting around 280 million people worldwide. This complex entity is the result of the interplay between biological, psychological, and sociocultural factors, and compelling evidence suggests that MDD can be considered a disease that occurs as a consequence of an evolutionary mismatch and unhealthy lifestyle habits. In this context, diet is one of the core pillars of health, influencing multiple biological processes in the brain and the entire body. It seems that there is a bidirectional relationship between MDD and malnutrition, and depressed individuals often lack certain critical nutrients along with an aberrant dietary pattern. Thus, dietary interventions are one of the most promising tools to explore in the field of MDD, as there are a specific group of nutrients (i.e., omega 3, vitamins, polyphenols, and caffeine), foods (fish, nuts, seeds fruits, vegetables, coffee/tea, and fermented products) or dietary supplements (such as S-adenosylmethionine, acetyl carnitine, creatine, amino acids and so on.
  • 472
  • 04 Aug 2022
Topic Review
Mild Cognitive Impairment in Rural Areas
Mild cognitive or neurocognitive impairment (MCI) may be more prevalent in rural areas. Differences between rural and urban MCI patients in terms of risk factors, course and prognosis are rarely reported. 
  • 315
  • 04 Aug 2022
Topic Review
Effects of Particulate Matter on Inflammation and Thrombosis
Ambient air pollution has become a common problem worldwide. Exposure to pollutant particles causes many health conditions, having a particular impact on pulmonary and cardiovascular disease. Increased understanding of the pathological processes related to these conditions may facilitate the prevention of the adverse impact of air pollution on our physical health. 
  • 614
  • 04 Aug 2022
Topic Review
COVID-19 Effect on Fertility
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread over the world, having a huge impact on people’s lives and health. The respiratory system is often targeted in people with the coronavirus disease 2019 (COVID-19). The virus can also infect many organs and tissues in the body, including the reproductive system.
  • 423
  • 03 Aug 2022
Topic Review
Artisanal Beers
Beer is an alcoholic beverage frequently consumed globally. Special beers, known as artisanal, are progressively gaining consumer preference, opening up competition, and acquiring more space in the market.
  • 539
  • 01 Aug 2022
Topic Review
Health-Related Quality of Life of Patients with Tuberculosis
Tuberculosis (TB) is a major killer and cause of human suffering worldwide and imposes a substantial reduction in patients’ health-related quality of life (HRQoL). HRQoL indicates the consciousness of patients regarding their physical and mental health. HRQoL is markedly impaired in patients with TB. The factors affecting HRQoL differ with active and latent TB, socio-demographics, socio-economic status, presence of co-infections, etc.
  • 438
  • 01 Aug 2022
Topic Review
Child Waste Workers' Health Sufferings in South Asia
Child labor remains a health hazard, affecting the mental, physical, and emotional well-being of children. Children engage in waste management through various channels while constantly working to create a healthier and cleaner environment and exposing themselves to numerous health risks. 
  • 1.2K
  • 01 Aug 2022
Topic Review
Postpartum Relapse in Patients with Bipolar Disorder
Pregnancy and postpartum are vital times of greater vulnerability to suffer a decompensation of bipolar disorder (BD).
  • 530
  • 01 Aug 2022
Topic Review
Antibacterial Designs for Implantable Medical Devices
The uses of implantable medical devices are safer and more common since sterilization methods and techniques were established a century ago; however, device-associated infections (DAIs) are still frequent and becoming a leading complication as the number of medical device implantations keeps increasing.
  • 3.1K
  • 01 Aug 2022
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