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Topic Review
Postpartum Relapse in Patients with Bipolar Disorder
Pregnancy and postpartum are vital times of greater vulnerability to suffer a decompensation of bipolar disorder (BD).
  • 548
  • 01 Aug 2022
Topic Review
Congenital Afibrinogenemia and Hypofibrinogenemia
Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative and qualitative disorders. The clinical phenotype is highly heterogeneous, being associated with bleeding, thrombosis, or absence of symptoms. Afibrinogenemia and hypofibrinogenemia are the consequence of mutations in the homozygous, heterozygous, or compound heterozygous state in one of three genes encoding the fibrinogen chains, which can affect the synthesis, assembly, intracellular processing, stability, or secretion of fibrinogen. In addition to standard coagulation tests depending on the formation of fibrin, diagnostics also includes global coagulation assays, which are effective in monitoring the management of replacement therapy. Genetic testing is a key point for confirming the clinical diagnosis. The identification of the precise genetic mutations of congenital fibrinogen disorders is of value to permit early testing of other at risk persons and better understand the correlation between clinical phenotype and genotype.
  • 548
  • 02 Mar 2022
Topic Review
The Concept of Postbiotics
In 2021, the International Scientific Association for Probiotics and Prebiotics (ISAPP) defined a postbiotic as “a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. This definition of postbiotic requires that the whole or components of inactivated microbes be present, with or without metabolic end products. The definition proposed by ISAPP is comprehensive enough to allow the development of postbiotics from different microorganisms, to be applied in different body sites, encouraging innovation in a promising area for any regulatory category and for companion or production animals, and plant or human health. From a technological perspective, probiotic products may contain inanimate microorganisms, which have the potential to impart a health benefit. However, their contribution to health in most cases has not been established, even if at least one probiotic has been shown to confer the same health benefit by live or inanimate cells.
  • 547
  • 28 Jun 2022
Topic Review
Neurobehavioral Phenotype and Dysexecutive Syndrome of Preterm Children
The neurodevelopmental outcome of the premature infant is characterized by a set of minor-to-moderate dysfunctions in the developmental fields (language, praxis, executive, behavioral and attention disorders, social interaction disorders, etc.). These dysfunctions tend to cumulate, even to potentiate, which impacts school learning and the daily life of these children and their parents. Executive functions, such as high-level cognitive operations, play a preponderant role in learning and social adaptation via the regulation of children’s behavior and emotions. Thus, the notion of executive dysfunctions as an underlying mechanism of neurodevelopmental difficulties in VP children is now well documented. Executive deficit is central to the neurodevelopmental phenotype of preterm infants and their learning difficulties, both from a cognitive and a behavioral or social point of view.
  • 547
  • 25 Mar 2022
Topic Review
Artisanal Beers
Beer is an alcoholic beverage frequently consumed globally. Special beers, known as artisanal, are progressively gaining consumer preference, opening up competition, and acquiring more space in the market.
  • 547
  • 01 Aug 2022
Topic Review
Spiritual Needs in Post-Secular Contexts
It was found that it can be challenging to incorporate spiritual care in daily practice, not least in post-secular, culturally entwined, and pluralist contexts.
  • 547
  • 01 Mar 2022
Topic Review
Home Confinement Psychological-Influence during COVID-19
Home confinement and social distancing are two of the main public health measures to curb the spread of SARS-Cov-2, which can have harmful consequences on people’s mental health. This systematic review aims to identify the best available scientific evidence on the impact that home confinement and social distancing, derived from the SARS-CoV-2 pandemic, have had on the mental health of the general population in terms of depression, stress and anxiety.
  • 546
  • 29 Jun 2021
Topic Review
Diabetic Retinopathy Screening in Europe
Diabetic retinopathy (DR) is a leading cause of preventable vision impairment and blindness in the European Region. Despite the fact that almost all European countries have some kind of prophylactic eye examination for people with diabetes, the examinations are not properly arranged and are not organized according to the principles of screening in medicine. In 2021, the current COVID-19 pandemic moved telemedicine to the forefront healthcare services.
  • 546
  • 30 Jun 2021
Topic Review
Training on Cardiopulmonary Fitness
Heart failure (HF) is a common disease with an increasing prevalence worldwide and it is characterized by a low five-year survival of 35–55%, which affects cardiac function, exercise tolerance, and the daily life of patients. Cardiac rehabilitation is defined as a set of activities that aims to provide patients with heart disease with the best physical, mental, and social conditions, therefore, reducing the risk of death and acute events related to their illness. Previous studies have demonstrated that cardiac rehabilitation with physical exercise was beneficial to physical fitness, cardiac function, and quality of life in HF patients.
  • 548
  • 23 Jul 2021
Topic Review
Effect of Healthy Food/Beverages in Hospital Food Environment
The quality of the hospital food environment varies within and between facilities. Hospital visitors and employees are generally receptive to food environment interventions and a variety of designs can be used to improve the hospital food environment and increase the proportion of healthy purchases. The overall quality of hospital food environments varies. Educational, labelling, financial and choice architecture interventions were shown to improve the hospital food environment and/or dietary intake of consumers.
  • 546
  • 21 Apr 2022
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