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Topic Review
Molecular Techniques for Schistosomiasis
Diagnostic tools play a pivotal role in warfare against schistosomiasis but must adapt to the endemic status and objectives of activities. With the decrease of prevalence and infection intensity of schistosomiasis in human beings and livestock, optimal methodologies with high sensitivity and absolute specificity are needed for the detection of asymptomatic cases or light infections, as well as disease surveillance to verify elimination. In comparison with the parasitological methods with relatively low sensitivity and serological techniques lacking specificity, which both had been widely used in previous control stages, the molecular detection methods based on the amplification of promising genes of the schistosome genome may pick up the baton to assist the eventual aim of elimination.
  • 526
  • 29 Mar 2022
Topic Review
CRC and Gut Microbiota
The gut microbiota plays an important role in maintaining homeostasis in the human body, and the disruption of these communities can lead to compromised host health and the onset of disease.
  • 526
  • 23 Jun 2021
Topic Review
Physical Activity and Dementia
Physical activity (PA) has emerged as an alternative nonpharmacological approach to effectively address the effects of dementia. This is mainly because regular PA improves the strength of cells and tissues to respond to oxidative stress, vascularization, and energy metabolism and also allows neurotropic effects through neurotrophic factor (BDNF) concentrations, which contribute to brain plasticity, memory improvement, neurogenesis, and synaptic plasticity [15]. These processes attenuate for the loss of brain tissue while the brain is ageing [14]. 
  • 525
  • 24 Aug 2021
Topic Review
Marketing Unhealthy Foods to Children
HFSS food marketing featuring celebrities or influencers increases children’s food consumption, although this was from a limited number of studies. These findings suggest that limiting exposure of children to HFSS marketing including all celebrity types may have beneficial impacts upon dietary consumption. Further research on the impact of child characteristics such as SES, long-term impacts, and real-world studies would be beneficial to further inform the thinking of policy makers.
  • 525
  • 08 Feb 2022
Topic Review
Cytokines as Selected Biomarkers of Depression
Depression is one of the leading mental illnesses worldwide and lowers the quality of life of many. According to WHO, about 5% of the worldwide population suffers from depression. Studies report a staggering global prevalence of 27.6%, and it is rising. Professionally, depression belonging to affective disorders is a psychiatric illness, and the category of major depressive disorder (MDD) comprises various diagnoses related to persistent and disruptive mood disorders. Due to this fact, it is imperative to find a way to assess depression quantitatively using a specific biomarker or a panel of biomarkers that would be able to reflect the patients’ state and the effects of therapy. Cytokines, hormones, oxidative stress markers, and neuropeptides are studied in association with depression. 
  • 524
  • 31 Jan 2023
Topic Review
Whole Grain Consumption in Glycaemic Control
Whole grain consumption is beneficial for glucose metabolism in people with diabetes.
  • 524
  • 10 Jan 2022
Topic Review
Role of Glutathione in Food and Human Diseases
Glutathione is a naturally occurring compound that plays a crucial role in the cellular response to oxidative stress through its ability to quench free radicals, thus mitigating the risk of potential damage, including cell death. While glutathione is endogenously present in different plants and animal cells, their concentration varies considerably. The alteration in glutathione homeostasis can be used as a potential marker for human diseases. In the case of the depletion of endogenous glutathione, exogenous sources can be used to replenish the pool. To this end, both natural and synthetic glutathione can be used. 
  • 523
  • 13 Apr 2023
Topic Review
Electrochemical Sensors for Quantification of Glycated Hemoglobin
Glycated hemoglobin (HbA1c), one of the many variants of hemoglobin (Hb), serves as a standard biomarker of diabetes, as it assesses the long-term glycemic status of the individual for the previous 90–120 days. HbA1c levels in blood are stable and do not fluctuate when compared to the random blood glucose levels. The normal level of HbA1c is 4–6.0%, while concentrations > 6.5% denote diabetes. 
  • 521
  • 25 Feb 2023
Topic Review
Mutual Regulatory Mechanisms between N6-metyladenosine Modification and miRNAs
N6-metyladenosine (m6A), one of the most common RNA methylation modifications in mammals, has attracted extensive attentions owing to its regulatory roles in a variety of physiological and pathological processes. As a reversible epigenetic modification on RNAs, m6A is dynamically mediated by the functional interplay among the regulatory proteins of methyltransferases, demethylases and methyl-binding proteins. It has become increasingly clear that m6A modification is associated with the production and function of microRNAs (miRNAs).
  • 522
  • 10 Feb 2023
Topic Review
Classroom Active Desks
Classroom active desks refer to the desks placed in the classroom and can be moved in teaching activities. This entry was to examine the effects of active desks in the school setting on sedentary behavior, physical activity, academic achievements and overall health among children and adolescents aged 5–17 years. 
  • 522
  • 08 Apr 2021
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