Topic Review
Prediction Models for Venous Thromboembolism
Venous thromboembolism (VTE) is a significant cause of mortality in patients with lung cancer. Despite the availability of a wide range of anticoagulants to help prevent thrombosis, thromboprophylaxis in ambulatory patients is a challenge due to its associated risk of haemorrhage. As a result, anticoagulation is only recommended in patients with a relatively high risk of VTE. Efforts have been made to develop predictive models for VTE risk assessment in cancer patients, but the availability of a reliable predictive model for ambulate patients with lung cancer is unclear. 
  • 522
  • 05 Jul 2021
Topic Review
Anthocyanin
Anthocyanin is a natural soluble pigment in the flavonoid group. Approximately 635 or more structures have been found in nature and more than 30 types of anthocyanins and anthocyanidins have been identified based on the number and position of the hydroxyl group. The common aglycones are pelargonidin (Pg), cyanidin (Cy), peonidin (Pn), delphinidin (Dp), petunidin (Pt), and malvidin (Mv), but Cy-3-glucoside was widely distributed. Anthocyanins are mostly absorbed through the gastric wall with absorption rates of 10–22%, depending on chemical structure, and the bioavailability is approximately 0.26–1.8%. Anthocyanins produce antimicrobial, antioxidant, and anti-inflammatory effects and play a role in the prevention and treatment of numerous chronic conditions, such as obesity, diabetes mellitus (DM), cardiovascular disease (CVD), eye diseases, and in suppressing cancer cell growth.
  • 723
  • 05 Jul 2021
Topic Review
The Danish Pharmacy Practice Network
The Danish Network for Pharmacy Practice Research and Development (NUAP) is a network of Danish pharmacy owners and employees and Danish pharmacy practice researchers. The overall aim of the network is to strengthen pharmacy practice and pharmacy practice research in Denmark by providing a forum where researchers and representatives of community pharmacies meet to share knowledge and support evidence-based community pharmacy practice.
  • 496
  • 02 Jul 2021
Topic Review
Epilepsy in Down Syndrome
Individuals with Down syndrome (DS) have an increased risk for epilepsy during the whole lifespan, but especially after age 40 years. The increase in the number of individuals with DS living into late middle age due to improved health care is resulting in an increase in epilepsy prevalence in this population. However, these epileptic seizures are probably underdiagnosed and inadequately treated. This late onset epilepsy is linked to the development of symptomatic Alzheimer’s disease (AD), which is the main comorbidity in adults with DS.
  • 881
  • 02 Jul 2021
Topic Review
Pharmaceutical Care
Pharmaceutical care necessitates significant efforts from patients, informal caregivers, the interprofessional team of health care professionals and health care system administrators. Collaboration, mutual respect and agreement amongst all stakeholders regarding responsibilities throughout the complex process of pharmaceutical care is needed before patients can take full advantage of modern medicine. Based on the literature and policy documents, in this position paper, we reflect on opportunities for integrated evidence-based pharmaceutical care to improve care quality and patient outcomes from a nursing perspective.
  • 1.3K
  • 02 Jul 2021
Topic Review
Heart Rhythm Complexity and PH
Pulmonary hypertension (PH) is a progressive, complex, and fatal disease. It involves heterogenous etiologies and different mechanisms, and eventually leads to right heart failure. The mortality of PH patients is high even after contemporary treatment. A non-invasive and convenient tool can measure PH risk by assessing heart rate variability (HRV), namely, heart rhythm complexity analysis.
  • 498
  • 02 Jul 2021
Topic Review
Health-Related Quality of Life (HRQoL)
HRQoL is a multi-dimensional concept that reflects the degree to which a health condition interferes with participation in and fulfillment of important life areas. HRQoL is intended to capture the composite degree of physical, physiologic, psychological, and social impairment resulting from symptom burden, patient-perceived disease severity, and treatment side effects.
  • 452
  • 01 Jul 2021
Topic Review
Antimicrobial Use in COVID-19 Patients
There is an urgent need for further research and guidance in this field, from producing evidence-based guidelines, reassessing biomarkers for antimicrobial stewardship in COVID-19 patients, understanding drivers, benefits, and disbenefits of antibiotic use, and assessing the wider impact of the pandemic on antimicrobial use (AMU) and AMR. In this scoping review, we aim to: add to the research evidence on prevalence and patterns of antimicrobial use in the treatment of COVID-19 patients; identify the most commonly used antibiotics and clinical scenarios associated with AMU; and to explore any impact of AMU on patient treatment outcomes.
  • 475
  • 30 Jun 2021
Topic Review
Diabetic Retinopathy Screening in Europe
Diabetic retinopathy (DR) is a leading cause of preventable vision impairment and blindness in the European Region. Despite the fact that almost all European countries have some kind of prophylactic eye examination for people with diabetes, the examinations are not properly arranged and are not organized according to the principles of screening in medicine. In 2021, the current COVID-19 pandemic moved telemedicine to the forefront healthcare services.
  • 561
  • 30 Jun 2021
Topic Review
PCN in Malignancy-Associated Ureteric Obstruction
Malignant ureteric obstruction occurs in a variety of cancers and has been typically associated with a poor prognosis. Percutaneous nephrostomy (PCN) can potentially help increase patient longevity by establishing urinary drainage and treating renal failure. PCN is to put a small tube through a kidney to drain urine.
  • 587
  • 29 Jun 2021
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