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All Topic Review Biography
Topic Review
Mild Cognitive Impairment in Rural Areas
Mild cognitive or neurocognitive impairment (MCI) may be more prevalent in rural areas. Differences between rural and urban MCI patients in terms of risk factors, course and prognosis are rarely reported. 
  • 351
  • 04 Aug 2022
Topic Review
Source of Discomfort in Police Officers
The importance of improving working conditions for the health and psychological health of police officers creates added value in terms of organizational performance and the quality of life of those in the organization. Protecting the psychological health of police officers could have a positive impact not only on the private lives of employees but also on the quality of the relations between police officers and the users of police services, which, in turn, may lead to an improvement in the services offered to citizens. It is therefore desirable that all police organizations become aware of the importance of psychosocial risk assessment for not only the protection of police officers’ health but also for the optimization of their responses to citizens’ requests.
  • 351
  • 27 May 2022
Topic Review
Bempedoic Acid and Statins in Lipid-Lowering Strategy
Pharmacological research has led to the development of a new drug, the bempedoic acid, which further enrich the available therapies. This drug also acts on the biosynthesis of cholesterol but at upstream level than statins. From the biochemical point of view, it has the potential to be considered before the statin with consequent titration of statins to achieve the desirable LDL-C target. 
  • 351
  • 06 May 2023
Topic Review
Radon and Non-Pulmonary Neoplasm Risk
Although Radon (Rn) is a known agent for lung cancer, the link between Rn exposure and other non-pulmonary neoplasms remains unclear. The aim of this review is to investigate the role of Rn in the development of tumors other than lung cancer in both occupational and environmental exposure.  
  • 350
  • 22 Oct 2021
Topic Review
Rehabilitation of Motor Impairment in Stroke
Stroke is categorized as one of the most concerning global health issues as it is a serious and common disabling factor worldwide. Ageing and urbanization are two powerful drivers of stroke. The elderly population is at higher risk of experiencing a stroke, but stroke can be prevented to some extent by dealing with the modifiable menace factors such as physical inactivity, drugs, unhealthy diet, and tobacco so that problems such as hypertension, high blood pressure, and diabetes, which are the root causes of the epidemic, may be managed. Different therapies are described, such as functional electric stimulation (FES), noninvasive brain stimulation (NIBS) including transcranial direct current stimulation (t-DCS) and transcranial magnetic stimulation (t-MS), invasive epidural cortical stimulation, virtual reality (VR) rehabilitation, task-oriented therapy, robot-assisted training, tele rehabilitation, and cerebral plasticity for the rehabilitation of upper extremity motor impairment. New therapeutic rehabilitation techniques are also being investigated, such as VR. 
  • 350
  • 11 Feb 2022
Topic Review
Personalization of Therapy in High-Grade Serous Tubo-Ovarian Cancer
High-grade serous tubo-ovarian cancer (HGSTOC) is the most lethal tumor of the female genital tract. The foregoing therapy consists of cytoreduction followed by standard platinum/taxane chemotherapy; alternatively, for primary unresectable tumors, neo-adjuvant platinum/taxane chemotherapy followed by delayed interval cytoreduction. In patients with suboptimal surgery or advanced disease, different forms of targeted therapy have been accepted or tested in clinical trials. Studies on HGSTOC discovered its genetic and proteomic heterogeneity, epigenetic regulation, and the role of the tumor microenvironment. These findings turned attention to the fact that there are several distinct primary tumor subtypes of HGSTOC and the unique biology of primary, metastatic, and recurrent tumors may result in a differential drug response. This results in both chemo-refractoriness of some primary tumors and, what is significantly more frequent and destructive, secondary chemo-resistance of metastatic and recurrent HGSTOC tumors. Treatment possibilities for platinum-resistant disease include several chemotherapeutics with moderate activity and different targeted drugs with difficult tolerable effects. Therefore, the question appears as to why different subtypes of ovarian cancer are predominantly treated based on the same therapeutic schemes and not in an individualized way, adjusted to the biology of a specific tumor subtype and temporal moment of the disease.
  • 350
  • 05 Jan 2024
Topic Review
Service Quality of Healthcare Research Domain
Hospital care and other services have become increasingly important for patient satisfaction. Better hospital care and assistance improve patients’ medical conditions, management trust, and financial success. In this regard, monitoring and measuring hospital service quality is necessary to improve patient satisfaction and wellness. However, the evaluation of healthcare service quality is a complex and critical task due to its intangible nature.
  • 349
  • 06 Nov 2023
Topic Review
Opioids and Agricultural Industries
The rising incidence of opioid use and its associated aftermath have been deemed a public health crisis in the U.S. The term opioid encompasses prescription opioid medication (used to treat pain, most commonly oxycodone and hydrocodone), the synthetic opioid fentanyl (used for severe pain), and heroin (an illegal opioid in the U.S.). Given the potentially destructive nature of opioids and the importance of agricultural industries to the well-being and security of U.S. residents, it is important to gain a better understanding of the impact of harmful opioid use on agricultural industries as well as areas of need for resource and program development. Levels of opioid use and associated consequences vary tremendously by location even within a given state. Indeed, opioid use and associated issues tend to vary by urban and rural areas, with differing risk factors, consequences, and resources.
  • 349
  • 19 May 2022
Topic Review
Health in Chile’s Constitutional Process
Chile is a high-income country in Latin America that faces great socioeconomic inequality and a segmented–public and private–health system. In response to the serious political crisis which took place in 2019, Chile’s political parties came together to deliberate on an institutional solution, attending to the social demands of fairness around several issues, such as pensions, health, and education. The result was the elaboration of the “Agreement for Social Peace and the New Constitution’’. In the process towards elaborating a draft for a new constitution, different mechanisms of civil participation were enabled, including the Popular Initiatives for Norms, an online website where individuals or collectives could submit proposals to be considered.
  • 349
  • 03 Jan 2023
Topic Review
Treatment of Halitosis
Halitosis, or bad breath, is an oral health problem characterized by an unpleasant malodor emanating from the oral cavity. This condition can have different origins and causes a negative burden in social interactions, communication and quality of life, and can in uncommon cases be indicative of underlying non-oral non-communicable diseases.
  • 349
  • 21 Sep 2022
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