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Topic Review
Anxiety, Depressive Symptoms and Stress in Chronic Pain
Anxiety, depressive symptoms and stress have a significant influence on chronic musculoskeletal pain. Behavioral modification techniques have proven to be effective to manage these variables; however, the COVID-19 pandemic has highlighted the need for an alternative to face-to-face treatment.
  • 456
  • 24 Mar 2022
Topic Review
Placental Evaluation In Vivo Models to Evaluate Nanocarriers
Pregnancy-associated disorders affect around 20% of pregnancies each year around the world. The risk associated with pregnancy therapeutic management categorizes pregnant women as “drug orphan” patients. In the last few decades, nanocarriers have demonstrated relevant properties for controlled drug delivery, which have been studied for pregnancy-associated disorders. To develop new drug dosage forms it is mandatory to have access to the right evaluation models to ensure their usage safety and efficacy. 
  • 456
  • 27 Apr 2022
Topic Review
COVID-19 Effect on Fertility
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread over the world, having a huge impact on people’s lives and health. The respiratory system is often targeted in people with the coronavirus disease 2019 (COVID-19). The virus can also infect many organs and tissues in the body, including the reproductive system.
  • 455
  • 03 Aug 2022
Topic Review
Long COVID
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was first detected in China in a group of patients suffering from pneumonia. It was established as the causative agent for COVID-19, the virus that led to the ongoing pandemic, and the recently raised threat of long COVID-19. Even though some cases can progress to life-threatening pneumonia, most individuals infected with the virus suffer from mild to moderate illness.
  • 455
  • 31 Oct 2022
Topic Review
Drosophila with Super-Resolution Microscopy
In recent decades, fluorescent microscopy has become the most popular tool of cell and developmental biologists, since fluorescent labeling offers high molecular specificity, and due to its low invasiveness, it has become the leading method to study living cells, tissues or organisms. In the early days, only widefield applications were available, but with later technological advances, every aspect of microscopy was improved tremendously, resulting in the development of specialized microscopes, such as optical sectioning confocal microscopes, spinning disk confocal microscopes, light sheets, TIRF and multi-photon microscopic tools. Despite the remarkable progress, all these techniques remained limited by the wavelength of light at around 200-250 nm. A turning point came when scientists found ways to get around this obstacle and developed several nanoscopic methods that are able to increase the resolution up to 2-10 nm, allowing the study and understanding of the cellular structures at the molecular level by broadly applicable microscopic approaches.
  • 455
  • 09 Aug 2021
Topic Review
Buildings’ Sustainability after COVID-19
The concept of sustainability, or sustainable development, was introduced in 1987 through the UN Brundtland Report, in which it is defined as "development that meets the needs of the present without compromising the ability of future generations to meet their own needs". The link between COVID-19 and sustainability is made up of a variety of psycho-sociological and perceptual aspects, such as the fact that the occupancy pattern of buildings is one of the determining factors in assessing the energy performance and sustainability of buildings.
  • 454
  • 26 Feb 2024
Topic Review
Smoking Cessation Apps
Smoking cessation interventions are effective, but they are not easily accessible for all treatment-seeking smokers. Mobile health (mHealth) apps have been used in recent years to overcome some of these limitations. Smoking cessation apps can be used in combination with a face-to-face intervention (FFSC-Apps), or alone as general apps (GSC-Apps). Smartphone apps for smoking cessation could be promising tools. However, more research with an adequate methodological quality is needed to determine its effect. Nevertheless, smartphone apps’ high availability and attractiveness represent a great opportunity to reach large populations.
  • 454
  • 24 Dec 2021
Topic Review
Chronic Inflammation in Cancer Cachexia
Cachexia, a type of metabolic syndrome linked to the disease, is associated with a dysregulation of metabolic pathways. Cancer Cachexia is a subtle condition that reduces patients’ quality of life by impairing their response to therapy and survival. Inflammatory mediators that may play a role in the pathogenesis of neoplastic cachexia, for example, overlap with those that may play a role in the pathogenesis of obesity. Cachexia is a complication of cancer-related malnutrition associated with catabolic/hypermetabolic changes.
  • 454
  • 05 May 2022
Topic Review
Risk Factors for Testicular Cancer
A large piece of knowledge suggests that most testicular cancers originate from a potential noxa during fetal life. Nevertheless, the environment, familial history, ethnicity as well as diet and occupational exposures are other important actors involved in testis carcinogenesis. 
  • 454
  • 19 Jun 2023
Topic Review
NAFLD Distribution
Non-alcoholic fatty liver disease (NAFLD) is considered the liver manifestation of metabolic syndrome. Nowadays, its prevalence is 25% worldwide and it is projected to reach the 30% in 2030, making NAFLD an important public health issue. NAFLD prevalence can vary according to the region and the social group under study. In fact, NAFLD distribution shows large inequalities by social group: Males have higher NAFLD prevalence, although if only postmenopausal women are taken into account, the prevalence is similar between genders. In the US, the Hispanic population has the highest NAFLD prevalence and African-American the lowest. Finally, higher NAFLD prevalence has been found among individuals with lower socioeconomic positions and food-insecure households. 
  • 453
  • 24 Nov 2021
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