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All Topic Review Biography
Topic Review
Indolepropionic Acid and Risk of T2DM & NAFLD
Gut-derived metabolites such as indolepropionic acid (IPA) are known to paly an important contribution in the development of metabolic diseases. The source of IPA depends on the dietary tryptophan intake, especially fiber, and presence of specific bacterial species in the human gut. In the present narrative review we elaborate on the role of IPA in type 2 diabetes (T2D) as well as non-alcoholic fatty liver disease (NAFLD). Researchers further explored the association of IPA with well known T2D-genetic variants and IPA-linked mechanisms affecting glucose metabolism and liver fibrosis.
  • 463
  • 28 Nov 2022
Topic Review
Thalassotherapy for Improving Well-Being and Post-Oncology Recovery
Cancer treatments have undergone significant advances, although they are not exempt from side effects, including skin toxicity. Different studies show that skin care for cancer patients can be effective in reducing sequelae such as inflammation, xerosis, skin rash, and radiodermatitis, among others. It is necessary to implement measures that improve the patient’s well-being and, therefore, thalassotherapy techniques and the marine environment could be an effective resource to achieve this goal. Thalassotherapy is the combined use of marine elements (water, algae, mud and climate), in a marine environment for healing and well-being improvement purposes. 
  • 463
  • 31 Jan 2023
Topic Review
Volume and Surgical Outcomes in Gastric Cancer
Gastric cancer is ranked as the fifth most frequently diagnosed type of cancer. Complete resection with adequate lymphadenectomy represents the goal of treatment with curative intent. Quality assurance is a crucial factor in the evaluation of oncological surgical care, and centralization of healthcare in referral hospitals has been proposed in several countries. However, an international agreement about the setting of “high-volume hospitals” as well as “minimum volume standards” has not yet been clearly established. Despite the clear postoperative mortality benefits that have been described for gastric cancer surgery conducted by high-volume surgeons in high-volume hospitals, many authors have highlighted the limitations of a non-composite variable to define the ideal postoperative period.
  • 462
  • 05 May 2023
Topic Review
The Potential of Exerkines in Women’s COVID-19
Exerkines are a group of promising molecules that may underlie the beneficial effects of physical exercise in diseases. The idea of exerkines is to understand the effects of physical exercise on diseases better. Exerkines have a high potential for the treatment of diseases and, considering that, there is still no study of the importance of exerkines on the most dangerous disease in the world in recent years, COVID-19.
  • 462
  • 05 Dec 2022
Topic Review
Prevention of Heat-Related Illnesses
Extreme temperatures are known to have negative consequences on the environment and the ecosystem. Already more frequent and intense heat waves are likely to increase in the future due to a projected 0.1–0.2-degree Celsius rise in temperature by 2100. Extreme heat can lead to a spectrum of health-related conditions that range from mild to severe and include, but are not limited to, heat dehydration, cramps, exhaustion syncope and stroke; these are referred to as heat-related illnesses (HRIs).
  • 462
  • 10 Aug 2021
Topic Review
Sex Disparity in Cardiovascular Disease
Among cardiovascular diseases, acute myocardial infarction (AMI) shows significant differences in occurrence rate, prognosis and efficacy of treatment between male and female patients. Genomics and epigenomics approaches together with epidrugs design and drug repositioning could fill the sex-gap.
  • 462
  • 29 Mar 2022
Topic Review
Effectiveness of COVID-19 Vaccines against Delta (B.1.617.2) Variant
The high transmissibility, mortality, and morbidity rate of the SARS-CoV-2 Delta (B.1.617.2) variant have raised concerns regarding vaccine effectiveness (VE). The short-term effectiveness of the Pfizer-BioNTech, Moderna, AstraZeneca, Bharat Biotech, and CoronaVac vaccines for the prevention of infection and the reduction in the severity of illness and hospitalizations associated with the Delta variant are supported. 
  • 462
  • 06 Jan 2022
Topic Review
Effect of Sex Hormones on Migraine
Sex hormones and migraine are closely interlinked. Women report higher levels of migraine symptoms during periods of sex hormone fluctuation, particularly during puberty, pregnancy, and perimenopause. Ovarian steroids, such as estrogen and progesterone, exert complex effects on the peripheral and central nervous systems, including pain, a variety of special sensory and autonomic functions, and affective processing. A panel of basic scientists, when challenged to explain what was known about how sex hormones affect the nervous system, focused on two hormones: estrogen and oxytocin.
  • 462
  • 11 Mar 2024
Topic Review
Obstetric and Perinatal Outcomes Resulting from IVF Pregnancies
The number of pregnancies achieved using in vitro fertilization (IVF) is rapidly increasing around the world. The chance of obtaining a successful pregnancy is also significantly improved due to technological advances and improvement in infertility treatment. Despite this success, there is evidence that pregnancy conceived by IVF has an increased risk of adverse maternal and perinatal outcome mainly represented by the development of hypertensive diseases, pre-eclampsia, and fetal growth restriction. Although different cofactors may play a role in the genesis of these diseases, the development of the placenta has a pivotal function in determining pregnancy outcomes.
  • 462
  • 25 Oct 2022
Topic Review
Household Food Dynamics during COVID-19
Home confinement during the COVID-19 pandemic has been accompanied by dramatic changes in household food dynamics that can significantly influence health. Overall, families enjoyed more time together around food, including planning meals, cooking, and eating together. Eating more diverse foods and balanced home-cooked meals (e.g., fresh fruit and vegetables) was combined with overeating and increased snacking (e.g., high-calorie snacks, desserts, and sweets), as parents became more permissive towards food; however, food insecurity increased among families with the lowest income. Adoption of meal planning skills and online shopping behavior emerged alongside behaviors aimed at self-sufficiency, such as bulk purchasing and stockpiling of non-perishable processed foods. These results are an important first step in recognizing how this pandemic may be affecting the family food environment, including low-income families.
  • 462
  • 22 Sep 2022
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