Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Co-Adjuvant Drugs in Cancer Therapy
Repurposed agents have provided growing evidence of fast implementation in oncology treatment such as certain antimalarial, anthelmintic, antibiotics, anti-inflammatory, antihypertensive, antihyperlipidemic, antidiabetic agents. Despite the abundance of results from in vitro and in vivo studies, the only solid data from randomized clinical trials confirm metformin-related oncological benefits for only a small subset of nondiabetic patients with HER2-positive breast cancer and early-stage colorectal cancer. At the same time, clinical studies confirm metformin-related detrimental/lack of an effect for lung, breast, prostate cancer, and glioblastoma. For atorvastatin we see a clinical oncological benefit in patients and head and neck cancer, with a trend towards radioprotection of critical structures, thus supporting the role of atorvastatin as a promising agent for concomitant association with radiotherapy. Propranolol-related increased outcomes were seen in clinical studies in patients with melanoma, breast cancer, and sarcoma.
  • 476
  • 24 Oct 2022
Topic Review
PD-L1 in Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate of approximately 5–10%. The immune checkpoint blockade represented by PD-1/PD-L1 inhibitors has been effective in a variety of solid tumors. 
  • 476
  • 06 Dec 2022
Topic Review
Physical Therapy intervene Critically-Ill COVID-19
As part of COVID-19 consequences, it has been estimated that 5% of patients affected by this dis-ease will require admission to the intensive care unit (ICU), and physical therapy techniques have been implemented in patients with other conditions admitted to ICU.
  • 475
  • 02 Mar 2021
Topic Review
Health-Related Quality of Life (HRQoL)
HRQoL is a multi-dimensional concept that reflects the degree to which a health condition interferes with participation in and fulfillment of important life areas. HRQoL is intended to capture the composite degree of physical, physiologic, psychological, and social impairment resulting from symptom burden, patient-perceived disease severity, and treatment side effects.
  • 475
  • 01 Jul 2021
Topic Review
Gestational Diabetes Mellitus and Meconium Microbiota
Gestational diabetes mellitus (GDM) is a pregnancy complication in which women without previously diagnosed diabetes develop chronic hyperglycemia during gestation. Microbial organisms within the gut—the “gut microbiome”—might contribute to metabolic diseases, including GDM.
  • 475
  • 24 Mar 2022
Topic Review
Association between Dietary Inflammatory Index and Colorectal Cancer
The advent of the Dietary Inflammatory Index (DII) provides a quantitative means to study the relationship between the pro-inflammatory diet and CRC. It allows the assessment of the inflammatory potential of individual food items using an FFQ, by which a DII score can be calculated. A higher DII score suggests a stronger inflammatory potential of a food item. The Dietary Inflammatory Index (DII) was extensively used to examine the inflammatory potential of diet related to colorectal cancer (CRC).
  • 474
  • 13 Apr 2022
Topic Review
Association between NAFLD and Infectious Diseases
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, affecting one third of the Western population. The hallmark of the disease is excessive storage of fat in the liver. Most commonly, it is caused by metabolic syndrome (or one of its components).
  • 474
  • 23 Dec 2022
Topic Review
Thermal Comfort and Sleep Quality
Human comfort is determined based on their comfort level and overall satisfaction with the thermal environments. A stable core body temperature at about 37°C and maintained through a process that called Thermoregulation. In the process, the body would adjust to the thermal surrounding through efferent responses such as sweating or triggering adaptive action to be taken by each individual such as drinking water, having bath or etc. This is done so that are a certain level of comfort is reached in the cognitive process of a human that is called thermal comfort where comfort with surrounding temperature is archived physically, physiologically and psychologically.  Sleep is one of the most important aspects in daily life of a human being. It is classified into a few different stages, mainly Stage N1, N2, N3 and REM. This cycle alternates a few times during the whole sleep. An extreme cold environment would result in disrupted sleep quality as well as extreme hot environment. Thus, evaluating both thermal comfort and sleep quality are equally as important. In investigating thermal comfort with sleep quality, the method of questionnaire evaluation on the comfort of an individual have been the most used, since the thermal comfort considered as an individual perception. However, as the technology advances, other type of assessments are also used in addition to the traditional questionnaire evaluation method.
  • 473
  • 05 Sep 2021
Topic Review
IT-Driven Patient Agility and Digital Transformation
Modern hospitals are on the brink of a monumental change. They are currently exploring their options to digitally transform their clinical procedures and overall patient engagement. This work thoroughly investigates how hospital departments in the Netherlands can simultaneously leverage their strategic exploration of new IT resources and practices and exploit their current IT practices, i.e., IT ambidexterity, to drive digital transformation.
  • 473
  • 26 Apr 2022
Topic Review
Simulation-Based Education in Trauma Management
Trauma injuries are an important healthcare problem and one of the main leading causes of death worldwide. Researchers analyzed current practices in teaching trauma management using simulations, with the aim of summarizing them, identifying gaps and providing a critical overview on what has already been achieved.
  • 473
  • 25 Nov 2022
  • Page
  • of
  • 182
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
ScholarVision Creations
Feedback