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Topic Review
Adult Inpatients’ Perceptions of Their Fall Risk
Patient falls continue to be a high priority for healthcare organisations due to the detrimental physical, psychological, social and financial consequences that can occur.  A large number of falls in hospitals are unwitnessed and mostly occur due to patient behaviours and not seeking assistance. Understanding these patient behaviours may help to direct fall prevention strategies, with evidence suggesting the need to integrate patients’ perspectives into fall management. The qualitative and quantitative findings are organised into five domains: Fall Risk Perception Measures, Patients’ Perceptions of Fall Risk, Patients’ Perceptions of Falling in Hospital, Patients’ Fear of Falling and Barriers to Fall Prevention in Hospital. 
  • 317
  • 09 Jun 2022
Topic Review
Advanced Glycation End Products
Diabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first century due to its high mortality rates caused mainly due to its complications; therefore, the early identification of such complications becomes a race against time to establish a prompt diagnosis. The research of complications of DM over the years has allowed the development of numerous alternatives for diagnosis. Among these emerge the quantification of advanced glycation end products (AGEs) given their increased levels due to chronic hyperglycemia, while also being related to the induction of different stress-associated cellular responses and proinflammatory mechanisms involved in the progression of chronic complications of DM. Additionally, the investigation for more valuable and safe techniques has led to developing a newer, noninvasive, and effective tool, termed skin fluorescence (SAF).
  • 867
  • 10 Aug 2021
Topic Review
Advances in Non-Invasive Neuromodulation: Closed-Loop Vagus Nerve Stimulation
Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive neuromodulation therapy that eliminates the need for internal device implantation, presenting as a favorable therapeutic option. This method relies on electrical surface stimulation, bypassing the need for surgical procedures.
  • 149
  • 18 Jan 2024
Topic Review Peer Reviewed
Adverse Events Profile of COVID-19 Preventative Strategies
The COVID-19 pandemic has caused millions of deaths and has affected most people across the world, either directly or indirectly. Many preventative and therapeutic strategies have been employed since the beginning of the pandemic. With the development of the mRNA vaccine within a year of the start of the pandemic, we are entering a new era of vaccinology, and the adverse event profile of the COVID-19 vaccine is also becoming more apparent with time. While the benefits of the vaccines and other preventative strategies certainly outweigh the risk of adverse events, prospective clinical trials are urgently needed to determine whether specific populations, including those with a personal or family history of autoimmune disease, are at higher risk of developing certain adverse events, in order to minimize risk further.
  • 918
  • 13 Apr 2022
Topic Review
Adverse Perinatal Outcomes in COVID-19 Infected Pregnant Women
Several adverse maternal, fetal, and neonatal effects were significantly higher in COVID-19 infected pregnant women than non-infected. These included maternal death, preeclampsia, cesarean section delivery, fetal distress, preterm birth, low birth weight, stillbirth, low Apgar score at the fifth minute, and admission to NICU. The comorbidity conditions had no added risk of being infected with COVID-19 infection during pregnancy. Therefore, a COVID-19 infected pregnant woman should be treated with special precautions to avoid and minimize the identified adverse events during perinatal care. 
  • 470
  • 24 Jan 2022
Topic Review
Aeroterrestrial and Extremophilic Microalgae as Sources in Cosmetics
Microscopic prokaryotic and eukaryotic algae (microalgae), which can be effectively grown in mass cultures, are gaining increasing interest in cosmetics. Up to now, the main attention was on aquatic algae, while species from aeroterrestrial and extreme environments remained underestimated. In these habitats, algae accumulate high amounts of some chemical substances or develop specific compounds, which cause them to thrive in inimical conditions. Among such biologically active molecules is a large family of lipids, which are significant constituents in living organisms and valuable ingredients in cosmetic formulations. Therefore, natural sources of lipids are increasingly in demand in the modern cosmetic industry and its innovative technologies. Among novelties in skin care products is the use of lipid nanoparticles as carriers of dermatologically active ingredients, which enhance their penetration and release in the skin strata. 
  • 538
  • 29 Mar 2022
Topic Review
Aging and Quality of Life
The aging of the world’s population and the health problems accompanying it are becoming increasingly severe. Healthcare policies in developed countries focus on how to prevent and treat diseases associated with aging and how to maintain quality of life. Typical age-related diseases include deafness, cataracts, osteoarthritis, chronic obstructive pulmonary disease, diabetes mellitus, and dementia. Although the mechanisms by which these diseases develop differ, they are all caused by the accumulation of molecular and cellular damage over time.
  • 267
  • 07 Aug 2023
Topic Review
AI and Neural Network Algorithms
Al increases the potential of Micro-Electro-Mechanical System biosensors and opens up new opportunities for automation, consumer electronics, industrial manufacturing, defense, medical equipment, etc. Micro-Electro-Mechanical System microcantilever biosensors are currently making their way into the daily lives and playing a significant role in the advancement of social technology. Micro-Electro-Mechanical System biosensors with microcantilever structures have a num- ber of benefits over conventional biosensors, including small size, high sensitivity, mass production, simple arraying, integration, etc. These advantages have made them one of the development avenues for high-sensitivity sensors. The next generation of sensors will exhibit an intelligent development trajectory and aid people in interacting with other objects in a variety of scenario applications as a result of the active development of artificial intelligence (AI) and neural networks. A neural algorithm application in Micro-Electro-Mechanical System microcantilever biosensors is anticipated through the associated application of the principal com-ponent analysis approach. Researchers investigation has more scientific study value, because there are currently no favorable reports on the market regarding the use of AI with Micro-Electro-Mechanical System microcantilever sensors.
  • 347
  • 13 Sep 2022
Topic Review
AI and Radiomics in Bladder Cancer
The advent of artificial intelligence (AI) and radiomics in oncology marks a pivotal moment in the evolution of personalized medicine, particularly in the diagnosis and treatment of urological cancers such as bladder, kidney, and prostate cancer. These cutting-edge technologies are reshaping the foundations of cancer care, heralding a paradigm shift towards precision-driven methods. The diagnosis and treatment of bladder cancer have been profoundly transformed by the recent advancements in AI and radiomics.
  • 62
  • 27 Feb 2024
Topic Review
AI for Biomarker Analysis in Early Cancer Detection
Governments worldwide have prioritized multicancer early detection (MCED) for the better management of cancers. Artificial intelligence (AI) is a promising technology to enhance the performance of MCED. In the field of MCED, applying AI has also proven to be efficient in improving diagnostic performance. Harnessing AI has become a must-use technology in analyzing MCED data because MCED tools typically target tens of analytical targets. 
  • 64
  • 29 Feb 2024
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