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Topic Review
ACAD9 Deficiency
ACAD9 deficiency is a condition that varies in severity and can cause muscle weakness (myopathy), heart problems, and intellectual disability. Nearly all affected individuals have a buildup of a chemical called lactic acid in the body (lactic acidosis). Additional signs and symptoms that affect other body systems occur in rare cases.
  • 391
  • 23 Dec 2020
Topic Review
ACAN Gene
aggrecan
  • 373
  • 24 Dec 2020
Topic Review
Acanthamoeba Keratitis in Animals
When presented with an animal exhibiting signs of keratitis (inflammation of the cornea), such as impaired vision, mucoid discharges, redness, swelling, and corneal oedema, most veterinarians would think of bacteria, viruses, or fungi as the potential causative agent(s). Evidence has arisen in recent years of a possible connection between the protozoan Acanthamoeba and keratitis in animals. Acanthamoeba infection is underdiagnosed, but potentially common, in animals.
  • 534
  • 11 May 2021
Topic Review
Acanthamoeba spp.
Acanthamoeba spp. are free-living amoebas, which are widely distributed in soil, water, and air. They are capable of causing granulomatous amebic encephalitis, Acanthamoeba pneumonia, Acanthamoeba keratitis, and disseminated acanthamoebiasis.
  • 747
  • 18 Mar 2021
Topic Review
Acatalasemia
Acatalasemia is a condition characterized by very low levels of an enzyme called catalase. Many people with acatalasemia never have any health problems related to the condition and are diagnosed because they have affected family members.
  • 692
  • 04 Feb 2021
Topic Review
Accessory Gene Regulator Control in Staphylococcus aureus
Staphylococcus aureus is a leading global pathogen that causes a considerable and hard-to-estimate number of moderately severe skin infections, but also more severe and sometimes fatal infections of the blood, bones, and lungs. The accessory gene regulator (Agr) system is undoubtedly the best-studied staphylococcal regulatory system, both in terms of its quorum-sensing mechanism and regarding its regulon and mechanisms of target gene control. It consists of an operon of four genes, agrB, agrD, agrC, and agrA, which form the quorum-sensing circuit.
  • 342
  • 01 Mar 2023
Topic Review
Accumulation, Competition, and Toxicity of Divalent Cations
The binding of calcium and magnesium ions to proteins is crucial for regulating heart contraction. However, other divalent cations, including xenobiotics, can accumulate in the myocardium and enter cardiomyocytes, where they can bind to proteins.
  • 267
  • 20 Jul 2023
Topic Review
ACD/MPV
Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a disorder affecting the development of the lungs and their blood vessels. The disorder affects the millions of small air sacs (alveoli) in the lungs and the tiny blood vessels (capillaries) in the alveoli. It is through these alveolar capillaries that inhaled oxygen enters the bloodstream for distribution throughout the body and carbon dioxide leaves the bloodstream to be exhaled.
  • 503
  • 04 Jan 2021
Topic Review
ACE Gene
angiotensin I converting enzyme
  • 536
  • 04 Feb 2021
Topic Review
ACE2 and SARS-CoV-2
Angiotensin-Converting Enzyme 2 (ACE2) is an essential enzyme in the renin-angiotensin system (RAS), effectively maintaining RAS equilibrium. Recently, scientists have also found that through the mediation of the S protein, SARS-CoV-2 can invade host cells using ACE2 as the target.
  • 409
  • 23 Feb 2021
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