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Topic Review
Probiotics in cosmetics
Probiotics, defined as “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host,” are becoming increasingly popular and marketable. The cosmetic industry has harnessed this potential by producing products claiming to contain probiotics. However, not all products marketed as such comply with the requirements for this claim.  
  • 1.1K
  • 10 Mar 2021
Topic Review
Agroforestry
Agroforestry is recognized as a sustainable land use practice that creates more integrated, diverse, productive, profitable, healthy, sustainable land-use systems. However, the uptake of such a promising land use practice is slow. Through this research, carried out in a Terai district of Nepal, we thoroughly examine what influences farmers’ choice of agroforestry adoption and what discourages the adoption. For this, a total of 288 households were surveyed using a structured questionnaire. Two agroforestry practices were compared with conventional agriculture with the help of the Multinomial Logistic Regression (MNL) model. The likelihood of adoption was found to be influenced by gender: the male-headed households were more likely to adopt the tree-based farming practice. Having a source of off-farm income was positively associated with the adoption decision of farmers. Area of farmland was found as the major constraint to agroforestry adoption for smallholder farmers. Some other variables that affected positively included livestock herd size, provision of extension service, home-to-forest distance, farmers’ group membership and awareness of farmers about environmental benefits of agroforestry. Irrigation was another adoption constraint that the study area farmers were faced with. The households with a means of transport and with a larger family (household) size were found to be reluctant regarding agroforestry adoption. A collective farming practice could be a strategy to engage the smallholder farmers in agroforestry.
  • 1.1K
  • 16 Jan 2022
Topic Review
Encapsulation of Lipid-Soluble Bioactives
Lipid-soluble bioactives, such as vitamins A, E, D and K, carotenoids, polyunsaturated fatty acids (PUFA) and essential oils, are important nutrients in foods. However, their addition in food formulations, is often limited by limited solubility and high tendency for oxidation. Among the different encapsulation technologies, nanoemulsions are one of the most promising for protecting lipid-soluble bioactives.
  • 1.1K
  • 25 Oct 2020
Topic Review
Distribution of Sulfate-Reducing Bacteria in the Environment
Sulfate-reducing bacteria (SRB) are a heterogeneous group of anaerobic microorganisms that play an important role in producing hydrogen sulfide not only in the natural environment, but also in the gastrointestinal tract and oral cavity of animals and humans.
  • 1.1K
  • 25 Oct 2021
Topic Review
Bacterial Cellulose and Extracellular Matrixes Hydrogels
Application of biomaterials is one of the most innovative treatments for heart regeneration, involving the use of hydrogels from decellularized extracellular matrix, and their association with nanomaterials, such as alginate, chitosan, hyaluronic acid and gelatin. A promising material is bacterial cellulose hydrogel, due to its nanostructure and morphology being similar to collagen. Cellulose provides support and immobilization of cells, which can result in better cell adhesion, growth and proliferation, making it a safe and innovative material for cardiovascular repair.
  • 1.1K
  • 23 May 2022
Topic Review
The Mitochondrial Genome
Mitochondria are powerhouses of the cell and implement oxidative phosphorylation processes. Similar to plastids, mitochondria are endosymbionts of a pro-eukaryotic cell, have their own genome, and their own transcriptional and translational machinery.
  • 1.1K
  • 12 Jan 2023
Topic Review
Sex differences in umbilical cord
Biological differences between sexes should be considered in all stages of research, but there is still a lack of stratification by sex despite primary cultured cells retain memory of the sex and of the donor. The sex of donors in biological research must be known because variations in cells and cellular components can be used as end points, biomarkers and/or targets of pharmacological studies. This selective review focuses on the current findings regarding sex differences observed in the umbilical cord, a widely used source of research samples, both in the blood and in the circulating cells, as well as in the different cellular models obtainable from it. Moreover, an overview on sex differences in fetal programming is reported. As it emerges that the sex variable is still often forgotten in experimental models, we suggest that should be mandatory to adopt a sex oriented research, because only awareness of these issues can lead to innovative research.
  • 1.1K
  • 27 Jan 2021
Topic Review
Lactic Acid Bacteria against Mycotoxins
Mycotoxins (aflatoxin, ochratoxin, patulin, zearalenone, fumonisins, trichothecenes) are a large group of chemically diverse, non-protein, low-molecular secondary metabolites produced by molds. They constitute a global threat to human food and health. The generally regarded as safe (GRAS) status and long history as essential ingredients of fermented foods and probiotics make Lactic Acid Bacteria (LAB) a major biological tool against various food-related toxins. Numerous studies have shown LAB to be effective against all major mycotoxins.
  • 1.1K
  • 17 May 2022
Topic Review
Small-Molecule Therapeutic for Progeria Treatment
Hutchinson–Gilford progeria syndrome (HGPS), or progeria, is an extremely rare disorder that belongs to the class of laminopathies, diseases characterized by alterations in the genes that encode for the lamin proteins or for their associated interacting proteins. In particular, progeria is caused by a point mutation in the gene that codifies for the lamin A gene. This mutation ultimately leads to the biosynthesis of a mutated version of lamin A called progerin, which accumulates abnormally in the nuclear lamina. This accumulation elicits several alterations at the nuclear, cellular, and tissue levels that are phenotypically reflected in a systemic disorder with important alterations, mainly in the cardiovascular system, bones, skin, and overall growth, which results in premature death at an average age of 14.5 years. Unlike the majority of the rare diseases, it has, since November 2020, a specific FDA approved drug, lonafarnib. However, this small molecule represents a treatment, but it does not cure the disease, and it has several limitations that make the development of new therapeutic strategies a critical need in the field. 
  • 1.1K
  • 13 Jul 2021
Topic Review
Epigenetic Changes and Stress-Related Disorders
Stress is defined as a state of threatened or perceived as threatened homeostasis. Emerging evidence suggests that life-stress experiences can alter the epigenetic landscape and impact the function of genes involved in the regulation of stress response. More importantly, epigenetic changes induced by stressors persist over time, leading to increased susceptibility for a number of stress-related disorders.
  • 1.1K
  • 12 Jun 2021
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