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Topic Review
Biography
Topic Review
Tumor-Associated Macrophages in Targeting Solid Cancers
Macrophages are effector cells of the innate immune system, which can play a crucial role in the generation of anti-tumor immunity through their ability to phagocytose cancer cells and present tumor antigens to the cells of adaptive immunity. However, the macrophages that are recruited to the tumor microenvironment predominantly play pro-tumorigenic roles. Several strategies targeting pro-tumorigenic functions and harnessing the anti-tumorigenic properties of macrophages have shown promising results in preclinical studies, and a few of them have also advanced to clinical trials.
1.3K
06 Jan 2023
Topic Review
Oil Palm and Machine Learning
Machine learning (ML) offers new technologies in the precision agriculture domain with its intelligent algorithms and strong computation. Oil palm is one of the rich crops that is also emerging with modern technologies to meet global sustainability standards. This entry presents a comprehensive review of research dedicated to the application of ML in the oil palm agricultural industry over the last decade (2011–2020).
1.3K
16 Sep 2021
Topic Review
LC-MS Methods for Mycotoxins Detection in Food Products
Mycotoxins are a group of natural compounds produced under a wide range of climatic conditions by filamentous fungi mainly belonging to Aspergillus, Penicillium, Fusarium, Claviceps and Alternaria species. These toxins can contaminate various agricultural commodities (cereals, dried fruits, nuts, spices and coffee being the most frequently contaminated ones) either before harvest or under postharvest conditions, thus posing a risk to human and animal health due to their toxic effects.
1.3K
14 Jun 2022
Topic Review
Alien Insect Species for Food and Feed
While the use of alien insect species for food and feed can help to alleviate protein shortage and provide for a more sustainable feed production, their invasive potential should be considered.
1.3K
05 Jul 2022
Topic Review
NKT Cells
Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide range of the immune cells, including T cells, B cells, dendritic cells and macrophages. NKT cells can influence the status of the innate and adaptive immune systems because they secrete huge amounts of Th1 and Th2 cytokines. Earlier, the NKT cells were characterized by the NK and T cell properties as they express the natural killer (NK) cell lineage markers and αβ T-cell receptor (TCR). NKT cells are more appropriately defined as “CD1d-restricted and TCR-αβ positive T cells”. In mice, the NKT cells constitute about 0.2–2.0% of lymphocytes in the blood, spleen, bone marrow and thymus, and about 15–35% of total lymphocytes in the liver. On the other hand, the levels of NKT cells are lower in humans, comprising about 0.04–1.3% of circulating lymphocytes in the blood, spleen and bone marrow. They make up about 0.001–0.01% of lymphocytes in the thymus and about 1% in the liver. The greater part of the NKT cells, called canonical or invariant NKT cells (iNKT cells) or type I NKT cells have a specific TCR α-chain rearrangement (Vα14-Jα18 in mice; Vα24-Jα18 in humans), associated with limited diverse Vβ chains. Type II NKT cells, also called non-classical NKT cells, are more diverse in TCR α-chain (but some Vα3.2-Jα9, Vα8 in mice) and TCR-β chains (but some Vβ8.2 in mice).
1.3K
13 Sep 2021
Topic Review
Enzyme-Mediated Wastewater Remediation
Several additional treatments that could potentially supplement existing wastewater treatment plants (WWTPs) to eliminate pollutants include a range of physicochemical and biological methods. The use of enzymes, specifically, oxidoreductases, are increasingly being studied for their ability to degrade different classes of organic compounds. These enzymes have been immobilized on different supports to promote their adoption as a cost-effective and recyclable remediation approach. Unfortunately, some of these techniques have shown a negative effect on the enzyme, including denaturation and loss of catalytic activity.
1.3K
02 Dec 2021
Topic Review
Profiles of Underutilized Grain Crops
Underutilized grain crops are an essential part of the food system that supports humankind, such as barley, buckwheat, broomcorn millet, foxtail millet, oat, and sorghum, which have characteristics such as containing more nutritional elements, being resistant to biotic and abiotic stresses, and having strong adaptability to poor environments.
1.3K
29 Sep 2022
Topic Review
The Proteasome System
The proteasome system is a large and complex molecular machinery responsible for the degradation of misfolded, damaged, and redundant cellular proteins. When proteasome function is impaired, unwanted proteins accumulate, which can lead to several diseases including age-related and neurodegenerative diseases. Enhancing proteasome-mediated substrate degradation with small molecules may therefore be a valuable strategy for the treatment of various neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s diseases.
1.3K
24 Mar 2022
Topic Review
Morel Cultivation Industry in China
Morels are one of the most highly prized edible and medicinal mushrooms worldwide. Therefore, historically, there has been a large international interest in their cultivation. Numerous ecological, physiological, genetic, taxonomic, and mycochemical studies have been previously developed. At the beginning of 21th century, China finally achieved artificial cultivation and started a high-scale commercial development in 2012. Due to its international interest, its cultivation scale and area expanded rapidly in this country. However, along with the massive industrial scale, a number of challenges, including the maintenance of steady economic profits, arise. In order to contribute to the solution of these challenges, formal research studying selection, species recognition, strain aging, mating type structure, life cycle, nutrient metabolism, growth and development, and multi-omics has recently been boosted.
1.3K
29 Aug 2023
Topic Review
Bagarius bagarius
(Hamilton, 1822)
B. bagarius (Hamilton, 1822) is a fish species that has huge potential as food and game fish in Bangladesh, Bhutan, India, and Nepal, but is encountering the threat of extinction in Bangladesh and throughout the world, which can be inferred from its alarming conservation status in Bangladesh as well as throughout the world. It is known as “Baghair” or “Bagh mach” in Bangladesh. In Bangla, the term “Bagh” refers to a tiger.
1.3K
22 Apr 2022
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