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Topic Review
Cyrillic Script
The Cyrillic script (/sɪˈrɪlɪk/ sə-RIL-ik) is a writing system used for various languages across Eurasia and is used as the national script in various Slavic, Turkic, Mongolic, Uralic, Caucasian and Iranic-speaking countries in Southeastern Europe, Eastern Europe, the Caucasus, Central Asia, North Asia and East Asia. (As of 2019), around 250 million people in Eurasia use Cyrillic as the official script for their national languages, with Russia accounting for about half of them. With the accession of Bulgaria to the European Union on 1 January 2007, Cyrillic became the third official script of the European Union, following the Latin and Greek alphabets. In the 9th century AD, the Bulgarian tsar Simeon I the Great – following the cultural and political course of his father Boris I – commissioned a new script, the Early Cyrillic alphabet, to be made at the Preslav Literary School in the First Bulgarian Empire, which would replace the Glagolitic script, produced earlier by Saints Cyril and Methodius and the same disciples that created the new Slavic script in Bulgaria. The usage of the Cyrillic script in Bulgaria was made official in 893. The new script became the basis of alphabets used in various languages, especially those of Orthodox Slavic origin, and non-Slavic languages influenced by Bulgarian. For centuries Cyrillic was used by Catholic and Muslim Slavs too (see Bosnian Cyrillic). Cyrillic is derived from the Greek uncial script, augmented by letters from the older Glagolitic alphabet, including some ligatures. These additional letters were used for Old Church Slavonic sounds not found in Greek. The script is named in honor of the Saint Cyril, one of the two Byzantine brothers, Saints Cyril and Methodius, who created the Glagolitic alphabet earlier on. Modern scholars believe that Cyrillic was developed and formalized by the early disciples of Cyril and Methodius in the Preslav Literary School, the most important early literary and cultural centre of the First Bulgarian Empire and of all Slavs. The school developed the Cyrillic script: The earliest datable Cyrillic inscriptions have been found in the area of Preslav. They have been found in the medieval city itself, and at nearby Patleina Monastery, both in present-day Shumen Province, in the Ravna Monastery and in the Varna Monastery. With the orthographic reform of Saint Evtimiy of Tarnovo and other prominent representatives of the Tarnovo Literary School (14th and 15th centuries) such as Gregory Tsamblak or Constantine of Kostenets the school influenced Russian, Serbian, Wallachian and Moldavian medieval culture. That is famous in Russia as the second South-Slavic influence. In the early 18th century, the Cyrillic script used in Russia was heavily reformed by Peter the Great, who had recently returned from his Grand Embassy in Western Europe. The new letterforms, called the Civil script, became closer to those of the Latin alphabet; several archaic letters were abolished and several letters were designed by Peter himself. Letters became distinguished between upper and lower case. West European typography culture was also adopted. The pre-reform forms of letters called 'Полуустав' were notably kept for use in Church Slavonic and are sometimes used in Russian even today, especially if one wants to give a text a 'Slavic' or 'archaic' feel.
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  • 22 Nov 2022
Topic Review
White–Juday Warp-Field Interferometer
The White–Juday warp-field interferometer is an experiment designed to detect a microscopic instance of a warping of spacetime. If such a warp is detected, it is hoped that more research into creating an Alcubierre warp bubble will be inspired. A research team led by Harold "Sonny" White in collaboration with Dr. Richard Juday at the NASA Johnson Space Center and Dakota State University are conducting experiments, but results so far have been inconclusive.
  • 8.6K
  • 24 Nov 2022
Topic Review
Natural Biopolymers
Natural biopolymers are an interesting resource for edible films production, as they are environmentally friendly packaging materials.
  • 8.6K
  • 23 Jun 2021
Topic Review
Kilowatt Hour
The kilowatt hour (symbol: kW⋅h, kW h, or kWh) is a unit of energy equal to 3.6 megajoules. If energy is transmitted or used at a constant rate (power) over a period of time, the total energy in kilowatt hours is equal to the power in kilowatts multiplied by the time in hours. The kilowatt hour is commonly used as a billing unit for energy delivered to consumers by electric utilities.
  • 8.6K
  • 14 Nov 2022
Topic Review
Melatonin Protects Mitochondria and Adenosine Triphosphate Production
Melatonin (N-acetyl-5-methoxytryptamine) is a ubiquitous, mitochondria-targeted molecule present in all tested eukarya and bacteria. In March 2022, the first discovery of the serotonin N-acetyltransferase (SNAT) gene—responsible for the penultimate formation of N-acetylserotonin (NAS) before its final conversion into melatonin — in archaea further consolidates the status of melatonin as a regulator of biomolecular condensates in all three domains of life in the cellular empire. RNA viruses including SARS-CoV-2 contain proteins with intrinsically disordered regions that undergo liquid-liquid phase separation (LLPS). Liquid-liquid phase separation (LLPS) of these proteins form membraneless condensates that act as “viral factories” to facilitate and enhance replication. Phase separation of the SARS-CoV-2 nucleocapsid (N) protein is associated with mitochondrial dysfunction and rewiring of energy production away from oxidative phosphorylation (OXPHOS) to favor aerobic glycolysis in cytoplasm. Increased adenosine triphosphate (ATP) in cytoplasm supports viral replication. Melatonin protects mitochondria from damage, maintains adequate levels to disassemble “viral factories”, and prevents suppression of host antiviral immune responses by inhibiting nucleocapsid phase separation via antioxidant-dependent and -independent means.
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  • 05 Sep 2022
Topic Review
Compass Card (TransLink)
The Compass Card is a contactless smart card payment system primarily used for public transit in Metro Vancouver, British Columbia, Canada. It is operated by TransLink. Riders purchase a Compass Card and add fare value online, by phone, or at vending machines located at SeaBus terminals, SkyTrain and West Coast Express stations. Vending machines are also available at 18 participating London Drugs retail store locations. Compass Cards were deployed in August 2015. Full deployment for the general public took place on November 2, 2015. Since April 4, 2016, Compass Cards and Tickets have been required for all trips taken on the SkyTrain, SeaBus, and West Coast Express. In June 2016, TransLink reported that 100 percent of monthly pass users and 95 percent of all other users have switched over to the new format, totalling more than 915,000 customers.
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  • 14 Oct 2022
Topic Review
Classical Nucleation Theory
Crystal nucleation determining the formation and assembly pathway of first organic materials is the central science of various scientific disciplines such as chemical, geochemical, biological, and synthetic materials. Classical nucleation theory (CNT)  applies to systems of small organic molecules with an emphasis on the molecular interpretation of nucleation kinetics. CNT holds that density fluctuations are concomitant with the development of crystalline order. In other words, a crystal nucleus has an identical structure to its bulk crystal. 
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  • 22 Jul 2022
Topic Review
Social Control
Social control refers to the mechanisms, norms, and practices through which societies regulate individual behavior and maintain order. It encompasses both formal institutions such as laws and regulations, as well as informal social norms and expectations. Social control mechanisms serve to reinforce conformity to societal norms, values, and expectations, while also deterring deviant behavior through sanctions and rewards.
  • 8.6K
  • 26 Jan 2024
Biography
Bill Maher
William Maher (/mɑːr/; born January 20, 1956)[1] is an American comedian, political commentator, and television host. He is known for the HBO political talk show Real Time with Bill Maher (2003–present) and the similar late-night show called Politically Incorrect (1993–2002), originally on Comedy Central and later on ABC. Maher is known for his political satire[2] and sociopolitical comme
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  • 29 Nov 2022
Topic Review
Peroxisomal β-Oxidation
It is not paradoxical that what has been overlooked tends to be of great importance. Peroxisomes, the widely distributed organelles in the body, play irreplaceable roles in cellular metabolism, especially in fatty acid oxidation (FAO) and the generation and elimination of reactive oxygen species (ROS).
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  • 15 Jul 2022
Topic Review
Natural Emulsion Stabilizers
Natural emulsion stabilizers are polymers of amino acid, nucleic acid, carbohydrate, etc., which are derived from microorganisms, bacteria, and other organic materials. Plant and animal proteins are basic sources of natural emulsion stabilizers. Pea protein-maltodextrin and lentil protein feature entrapment capacity up to 88%, (1–10% concentrated), zein proteins feature 74–89% entrapment efficiency, soy proteins in various concentrations increase dissolution, retention, and stability to the emulsion and whey proteins, egg proteins, and proteins from all other animals are applicable in membrane formation and encapsulation to stabilize emulsion/nanoemulsion. In pharmaceutical industries, phospholipids, phosphatidyl choline (PC), phosphatidyl ethanol-amine (PE), and phosphatidyl glycerol (PG)-based stabilizers are very effective as emulsion stabilizers. Lecithin (a combination of phospholipids) is used in the cosmetics and food industries. Various factors such as temperature, pH, droplets size, etc. destabilize the emulsion. Therefore, the emulsion stabilizers are used to stabilize, preserve and safely deliver the formulated drugs, also as a preservative in food and stabilizer in cosmetic products. Natural emulsion stabilizers offer great advantages because they are naturally degradable, ecologically effective, non-toxic, easily available in nature, non-carcinogenic, and not harmful to health.
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  • 19 Jan 2022
Topic Review
Prehistoric Paintings in Magura Cave
The paintings are made of bat guano applied over limestone, therefore two sets of laboratory specimens were considered: stone specimens and stone specimens covered with a layer of sterilized bat guano. The two investigated treatments were a commercial product based on ethyl silicate (“ES”) and a solution of diammonium hydrogen phosphate (“DAP”), aimed at forming calcium phosphates. The results of the study indicate that both treatments were able to increase mechanical properties of stone, the increase being higher for “DAP”. Both consolidants caused acceptable color changes, but the “ES” treatment significantly decreased stone wettability, water absorption and water vapor permeability, while the “DAP” treatment slightly affected those properties. In the stone+guano specimens, the presence of the guano layer affected the penetration of the consolidants, thus partly reducing their effectiveness. Compared to the stone samples, the guano layer experienced a more intense color change, alongside visible cracking. However, the adopted methodology to replicate the cave paintings was not completely successful, as the so-deposited guano layer was very prone to detachment when dry, unlike cave paintings. Future work will be dedicated to assess the consolidant performance onto samples that resemble even more closely the conditions of the cave paintings, by improving the methodology for the guano layer deposition and by contaminating specimens with soluble salts before consolidant application.
  • 8.6K
  • 02 Nov 2020
Topic Review
Food Heritage
The entry explores the concept of food heritage, focusing mainly on the anthropological, geographical, and sociological debate. Although the review identifies some conceptualisations that frame heritage in the food and gastronomic domains, it also shows the high degree of fragmentation of the debate. In so doing, it sheds light on how the concept of food heritage from a theoretical point of view is still in progress.
  • 8.6K
  • 02 Feb 2022
Topic Review
SoundCloud
SoundCloud is an online audio distribution platform and music sharing website based in Berlin, Germany that enables its users to upload, promote, and share audio.
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  • 20 Oct 2022
Topic Review
Sone Ki Chidiya
"Sone Ki Chidiya" which means "A golden bird" but have you wondered why India was known by this name? Let's find out in this article
  • 8.6K
  • 06 May 2024
Topic Review
Essential Oil Prevents COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV‑2), also known as coronavirus disease-2019 (COVID-19), is a pandemic disease that has been declared as modern history’s gravest health emergency worldwide. Until now, no precise treatment modality has been developed. The angiotensin-converting enzyme 2 (ACE2) receptor, a host cell receptor, has been found to play a crucial role in virus cell entry; therefore, ACE2 blockers can be a potential target for anti-viral intervention. In this study, we evaluated the ACE2 inhibitory effects of 10 essential oils. Among them, geranium and lemon oils displayed significant ACE2 inhibitory effects in epithelial cells. In addition, immunoblotting and qPCR analysis also confirmed that geranium and lemon oils possess potent ACE2 inhibitory effects. Furthermore, the gas chromatography-mass spectrometry (GC–MS) analysis displayed 22 compounds in geranium oil and 9 compounds in lemon oil. Citronellol, geraniol, and neryl acetate were the major compounds of geranium oil and limonene that represented major compound of lemon oil. Next, we found that treatment with citronellol and limonene significantly downregulated ACE2 expression in epithelial cells. The results suggest that geranium and lemon essential oils and their derivative compounds are valuable natural anti-viral agents that may contribute to the prevention of the invasion of SARS-CoV-2/COVID-19 into the human body.
  • 8.6K
  • 13 Feb 2021
Topic Review
Correlation and Dependence
In statistics, correlation or dependence is any statistical relationship, whether causal or not, between two random variables or bivariate data. In the broadest sense correlation is any statistical association, though it commonly refers to the degree to which a pair of variables are linearly related. Familiar examples of dependent phenomena include the correlation between the height of parents and their offspring, and the correlation between the price of a good and the quantity the consumers are willing to purchase, as it is depicted in the so-called demand curve. Correlations are useful because they can indicate a predictive relationship that can be exploited in practice. For example, an electrical utility may produce less power on a mild day based on the correlation between electricity demand and weather. In this example, there is a causal relationship, because extreme weather causes people to use more electricity for heating or cooling. However, in general, the presence of a correlation is not sufficient to infer the presence of a causal relationship (i.e., correlation does not imply causation). Formally, random variables are dependent if they do not satisfy a mathematical property of probabilistic independence. In informal parlance, correlation is synonymous with dependence. However, when used in a technical sense, correlation refers to any of several specific types of mathematical operations between the tested variables and their respective expected values. Essentially, correlation is the measure of how two or more variables are related to one another. There are several correlation coefficients, often denoted [math]\displaystyle{ \rho }[/math] or [math]\displaystyle{ r }[/math], measuring the degree of correlation. The most common of these is the Pearson correlation coefficient, which is sensitive only to a linear relationship between two variables (which may be present even when one variable is a nonlinear function of the other). Other correlation coefficients – such as Spearman's rank correlation – have been developed to be more robust than Pearson's, that is, more sensitive to nonlinear relationships. Mutual information can also be applied to measure dependence between two variables.
  • 8.6K
  • 14 Oct 2022
Topic Review
Extreme Weather Events of 535–536
The extreme weather events of 535–536 were the most severe and protracted short-term episodes of cooling in the Northern Hemisphere in the last 2,000 years. The event is thought to have been caused by an extensive atmospheric dust veil, possibly resulting from a large volcanic eruption conjectured to be either in Asia, the Americas, Europe, or other locations. Its effects were widespread, causing unseasonable weather, crop failures, and famines worldwide.
  • 8.6K
  • 23 Nov 2022
Topic Review
Lisbon Treaty
The Lisbon Treaty has brought significant changes to the institutional structure of the European Union. The traditional three pillar system has been abolished and provisions regarding formal Union institutions have been amended. The aim of this encyclopedia entry is to briefly describe the functioning of each of the formal EU institutions after the Lisbon amendment. More specifically, their main tasks and powers will be shortly presented, whilst more extensive bibliography will be provided. In this regard, the reader will be in position to understand the fundamentals of the EU institutional structure and also find valuable sources for further research.
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  • 16 Mar 2021
Topic Review
Expectation–Disconfirmation Theory and Brand
Combining brand equity indicators with Expectation–Disconfirmation Theory (EDT) provides insight into the hardly measurable influential variables of brand loyalty and brand equity evaluation. The results suggest that the satisfaction level (i.e., product evaluation) can be explained in more depth by the divided response shift indicator in the case of a familiar, low involvement product such as mineral water. It can be stated that the positive and negative disconfirmations of the response shift, which measures the weight of a brand in the overall evaluation of a product, can provide accurate information for brand managers.
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  • 26 Jul 2022
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