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Biography
Michael Eisen
Michael Bruce Eisen (born April 13, 1967) is an American computational biologist and the editor-in-chief of the journal eLife[1]. He is a professor of genetics, genomics and development at University of California, Berkeley.[2][3][4][5][6] He is a leading advocate of open access scientific publishing and is co-founder of Public Library of Science (PLOS). In 2018, Eisen announced his intention to
  • 1.3K
  • 07 Dec 2022
Biography
Ilan Sadeh
Ilan Sadeh (born June 1, 1953) is an Israeli IT theoretician, entrepreneur, and human rights activist. He holds the position of Associate Professor of Computer Sciences and Mathematics at the University for Information Science and Technology "St. Paul The Apostole"[1] in Ohrid, Republic of Macedonia. Sadeh was the first to claim publicly in the Israeli media that Israel has no right to be c
  • 1.3K
  • 29 Dec 2022
Topic Review
BioSD
The BioSample Database (BioSD) is a database at European Bioinformatics Institute for the information about the biological samples used in sequencing. It stores submitter-supplied metadata about the biological materials from which data stored in the National Center for Biotechnology Information’s (NCBI) primary data archives are derived. NCBI’s archives hosts data pertaining to diverse types of samples from many species, and as such the BioSample database is similarly diverse. Examples of a BioSample include a primary tissue biopsy, an individual organism or an environmental isolate. The BioSample database captures sample metadata in a structured way by encouraging use of controlled sample attribute field name vocabularies. This metadata is key in giving the sample data context, allowing it to be more fully understood, reused, and enables aggregation of disparate data sets. Sample metadata is linked to relevant experimental data across many archival databases relieving submitter burden by enabling one-time submission of sample description. They then can reference that sample, when necessary, when making data deposits to other archives. BioSample records are indexed and searchable, supporting cross-database queries by sample description.
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  • 02 Dec 2022
Biography
Anat Ninio
Anat Ninio (Hebrew: ענת ניניו‎; born August 10, 1944) is a professor emeritus of psychology at the Hebrew University of Jerusalem, Israel. She specializes in the interactive context of language acquisition, the communicative functions of speech, pragmatic development, and syntactic development. Ninio is best known for her work on joint picture-book reading of parents and young childre
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  • 29 Dec 2022
Biography
Hugo Lichte
Hugo Lichte (11 April 1891 in :de:Mengede, Germany − 27 July 1963 in Berlin, Germany) was a German physicist. He did pioneering work on the theory of sound propagation in the ocean and was a leading developer of motion picture technology during the transition from silent to sound film. Hugo Lichte studied mathematics, physics and chemistry at the University of Göttingen from 1909 to 1913.[
  • 1.3K
  • 15 Dec 2022
Biography
John Reppy
John D. Reppy (born February 16, 1931) is a physicist who studies the quantum properties of superfluids at Cornell University. He is also a notable rock climber of long standing, who established a number of widely known climbing routes particularly in the northeastern United States. In the 1950s and 60s, Reppy was active on Ragged Mountain in Connecticut where he collaborated on many first as
  • 1.3K
  • 16 Dec 2022
Biography
Olaf Lechtenfeld
Olaf Lechtenfeld is a German mathematical physicist, academic and researcher. He is a full professor at the Institute of Theoretical Physics at Leibniz University, where he founded the Riemann Center for Geometry and Physics.[1] Lechtenfeld’s research is focused on string theory, gauge theory and integrable models. He has published over 200 research papers on mathematical physics, classical a
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  • 30 Dec 2022
Biography
Kenneth W. Ford
Kenneth William Ford (born May 1, 1926) is an United States theoretical physicist, teacher, and writer, currently residing in Philadelphia, Pennsylvania. He was the first chair of the physics department at the University of California, Irvine, and later served as president of the New Mexico Institute of Mining and Technology (New Mexico Tech) and as Executive Director and CEO of the American Ins
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  • 07 Dec 2022
Biography
Ludwig Waldmann
Ludwig Waldmann (June 8, 1913 in Fürth – February 9, 1980) was a Germany physicist who specialized in transport phenomena in gases. He derived the Waldmann-Snider equation.[1] Waldmann completed his Ph.D.[2] under Arnold Sommerfeld at the University of Munich in 1938. He was Sommerfeld’s assistant, at the Institute of Theoretical Physics, from 1937 – 1939. Waldman had been the scribe[3
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  • 15 Dec 2022
Topic Review
Glycyrrhetinic Acid in Liver Cancer Therapy
Liver cancer is one of the most common causes of cancer mortality worldwide. Chemotherapy and radiotherapy are the conventional therapies generally employed in patients with liver tumors. The major issue associated with the administration of chemotherapeutics is their high toxicity and lack of selectivity, leading to systemic toxicity that can be detrimental to the patient’s quality of life. An important approach to the development of original liver-targeted therapeutic products takes advantage of the employment of biologically active ligands able to bind specific receptors on the cytoplasmatic membranes of liver cells. In this perspective, glycyrrhetinic acid (GA), a pentacyclic triterpenoid present in roots and rhizomes of licorice, has been used as a ligand for targeting the liver due to the expression of GA receptors on the sinusoidal surface of mammalian hepatocytes, so it may be employed to modify drug delivery systems (DDSs) and obtain better liver or hepatocyte drug uptake and efficacy.
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  • 11 Apr 2022
Topic Review
Yvelines
Yvelines (/iːvlɪnz/, /iːvlaɪnz/; French: [ivlin] (listen)) is a department in the western part of the Île-de-France region in Northern France. In 2016, it had a population of 1,431,808. Its prefecture is Versailles, home to the Palace of Versailles, the principal residence of the King of France from 1682 until 1789, a UNESCO World Heritage Site since 1979. Yvelines' subprefectures are Saint-Germain-en-Laye, Mantes-la-Jolie and Rambouillet.
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  • 11 Oct 2022
Biography
Richard Gordon
Richard (Dick) Gordon is an United States theoretical biologist. He was born in Brooklyn, New York on Nov 6, 1943, the eldest son of Jack Gordon, a salesman and American handball champion,[1] and artist Diana Gordon. He is married to retired scientist Natalie K Björklund with whom he cowrote his second book and several academic publications. He has three sons, Leland, Bryson and Chason Gordon a
  • 1.2K
  • 13 Dec 2022
Biography
David Dane
David Maurice Surrey Dane, MRCS CRCP MB Bchir MRCP MRCPath FRCPath FRCP (25 March 1923 – 9 April 1998) was a pre-eminent British pathologist and clinical virologist known for his pioneering work in infectious diseases including poliomyelitis and the early investigations into the efficacy of a number of vaccines. He is particularly remembered for his strategic foresight in the field of blood tr
  • 1.2K
  • 09 Dec 2022
Biography
Katrina Spade
Katrina Mogielnicki Spade (born September 9, 1977[1]) is an American designer, entrepreneur, and death care advocate.[2] Spade is the founder of Recompose, a public-benefit corporation developing a natural alternative to conventional cremation and burial. She was awarded the Echoing Green Climate Fellowship in 2014 and the Ashoka Fellowship in 2018 for her work.[3] Spade grew up in rural New
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  • 16 Dec 2022
Topic Review
Nature’s Role in Outdoor Therapies
Outdoor therapies are intentional therapeutic processes that are (1) place-based, (2) feature active bodily engagement, and (3) recognize nature-human kinship. Significant variety exists in practice, from walk and talk therapy, to expedition-based wilderness therapy, to garden and animal-assisted therapies. These approaches have shown improvement across a wide range of social, emotional, physical, physiological, and psychological outcomes and populations.
  • 1.2K
  • 20 May 2021
Biography
Stefan Ślopek
Stefan Ślopek (December 1, 1914 in Skawa near Kraków – 22 August 1995, Wrocław[1] was a Polish scientist specializing in clinical microbiology and immunology. He is the great grandson of Józef Juraszek Ślopek. He is buried in the Grabiszyński Cemetery in Wrocław. After he had completed his secondary education in Tarnopol, he started his medical studies at the Faculty of Medicine in
  • 1.2K
  • 27 Dec 2022
Biography
Robert Döpel
Georg Robert Döpel (3 December 1895 – 2 December 1982) was a Germany experimental nuclear physicist. He was a participant in a group known as the "first Uranverein", which was spawned by a meeting conducted by the Reichserziehungsministerium, in April 1939, to discuss the potential of a sustained nuclear reaction. He worked under Werner Heisenberg at the University of Leipzig, and he conducte
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  • 29 Nov 2022
Biography
Lina Stern
Lina Solomonovna Stern (or Shtern; Russian: Лина Соломоновна Штерн; 26 August 1878 – 7 March 1968) was a Soviet biochemist, physiologist and humanist whose medical discoveries saved thousands of lives at the fronts of World War II. She is best known for her pioneering work on the blood–brain barrier, which she described as hemato-encephalic barrier in 1921.[1] Born in
  • 1.2K
  • 08 Dec 2022
Topic Review
Harvestman Anatomy
Harvestmen (Opiliones) are an order of arachnids and share many common characteristics with other arachnids. However, several differences separate harvestmen from other arachnid orders such as spiders. The bodies of opliones are divided into two tagmata (arthropod body regions): the abdomen (opisthosoma) and the cephalothorax (prosoma). Unlike spiders, the juncture between the abdomen and cephalothorax is often poorly defined. Harvestmen have chelicerae, pedipalps and four pairs of legs. Most harvestmen have two eyes, although there are eyeless species.
  • 1.2K
  • 27 Oct 2022
Topic Review
Redundancy Principle
The redundancy principle in biology expresses the need of many copies of the same entity (cells, molecules, ions) to fulfill a biological function. Examples are numerous: disproportionate numbers of spermatozoa during fertilization compared to one egg, large number of neurotransmitters released during neuronal communication compared to the number of receptors, large numbers of released calcium ions during transient in cells and many more in molecular and cellular transduction or gene activation and cell signaling. This redundancy is particularly relevant when the sites of activation is physically separated from the initial position of the molecular messengers. The redundancy is often generated for the purpose of resolving the time constraint of fast-activating pathways. It can be expressed in terms of the theory of extreme statistics to determine its laws and quantify how shortest paths are selected. The main goal is to estimate these large numbers from physical principles and mathematical derivations. When large distance separate the source and the target (a small activation site), the redundancy principle explains that this geometrical gap can be compensated by large number. Had nature used less copies than normal, activation would have taken a much longer time, as finding a small target by chance is a rare events and falls into narrow escape problems.
  • 1.2K
  • 01 Dec 2022
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