You're using an outdated browser. Please upgrade to a modern browser for the best experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Native Hypovitaminosis D and CKD
Native hypovitaminosis D (n-hVITD) is frequently found from the early stages of chronic kidney disease (CKD) and its prevalence increases with CKD progression. 
  • 748
  • 02 Sep 2021
Topic Review
Brain Aging and Neurodegeneration Factors as Phytocheimcals Targets
Aging is a normal process in the life of any species. Still, some individuals experience early or premature aging and, thus, advanced age-associated diseases impacting the quality of their life, accompanied by enormous economic and social burdens. Therefore, it would be rational to mitigate aging processes, not only to support healthy aging but also to hamper age-associated diseases. During aging, different functional systems are affected interactively. These include the central nervous system (CNS), cardiovascular system, immune system, and the gut ecosystem. Additionally, the musculoskeletal system is prone to progressive weakening, causing movement problems that could intensify the aforementioned complications and increase the risk of all types of dementia, including Alzheimer’s disease.
  • 748
  • 14 Aug 2023
Topic Review
Sustainable Diets
A calorie-balanced diet mainly based on food of plant origin that would allow the attainment of 60% of daily caloric requirements and a low protein intake from animal foods (focusing in fish and poultry) could significantly reduce global morbi-mortality and the dietary environmental impact maintaining a framework of sustainability conditioned by the consumption of fresh, seasonal, locally produced and minimally packaged products. The implementation of sustainable diets requires working on the triangulation of concepts of food–health–environment from schools and that is permanently reinforced during all stages of the life by healthcare workers, who should establish the appropriate modifications according to the age, gender and health situation. 
  • 747
  • 23 Mar 2022
Topic Review
Etiopathogenic Factors for Obesity
Obesity is an abnormal or excessive accumulation of fat that represents a health risk, and it is characterized by reaching a body mass index (BMI) equal to or greater than 30 kg/m2. Obesity is a chronic disease of multifactorial etiology that involves an energy imbalance, genetic and epigenetic factors, alterations in glucose and lipid metabolism, disorders of adipose tissue functioning, neuroendocrine dysregulation, and alterations in the intestinal microbiota, among others.
  • 747
  • 05 Mar 2024
Topic Review
Non-Digestible Oligosaccharides
Emerging antimicrobial resistance in respiratory infections requires novel intervention strategies. Non-digestible oligosaccharides (NDOs) are a diverse group of carbohydrates with broad protective effects. In addition to promoting the colonization of beneficial gut microbiota and maintaining the intestinal homeostasis, NDOs act as decoy receptors, effectively blocking the attachment of pathogens on host cells. NDOs also function as a bacteriostatic agent, inhibiting the growth of specific pathogenic bacteria. Based on this fact, NDOs potentiate the actions of antimicrobial drugs. Therefore, there is an increasing interest in characterizing the anti-infective properties of NDOs.
  • 744
  • 13 Dec 2022
Topic Review
Microbiota in Shaping Women’s Health
A properly colonized human microbiota contributes to the proper functioning of the body. The composition of the natural flora changes depending on age, health, living conditions, and the use of antimicrobial agents: antibiotics, disinfectants, and some cosmetics. The human body is diversely populated with microorganisms and undergoes constant changes under the influence of various factors, and its proper composition is extremely important for the proper functioning of the body.
  • 743
  • 09 Jan 2023
Topic Review
Placental Amino Acid Transport
Intrauterine growth restriction (IUGR) is associated with reduced placental amino acid transport (AAT). However, it remains to be established if changes in AAT contribute to restricted fetal growth. We hypothesized that reduced in vivo placental AAT precedes the development of IUGR in baboons with maternal nutrient restriction (MNR). Baboons were fed either a control (ad libitum) or MNR diet (70% of control diet) from gestational day (GD) 30. At GD 140, in vivo transplacental AA transport was measured by infusing nine (13)C- or (2)H-labeled essential amino acids (EAAs) as a bolus into the maternal circulation at cesarean section. A fetal vein-to-maternal artery mole percent excess ratio for each EAA was measured. Microvillous plasma membrane (MVM) system A and system L transport activity were determined. Fetal and placental weights were not significantly different between MNR and control. In vivo, the fetal vein-to-maternal artery mole percent excess ratio was significantly decreased for tryptophan in MNR. MVM system A and system L activity was markedly reduced in MNR. Reduction of in vivo placental amino acid transport precedes fetal growth restriction in the non-human primate, suggesting that reduced placental amino acid transfer may contribute to IUGR.
  • 741
  • 10 Sep 2021
Topic Review
Plant-Based Diets in Black Populations
Plant-based diets are associated with reduced risks of various chronic diseases in the general population. However, it is unclear how these benefits translate to Blacks living in the United States, who are disproportionately burdened with heart disease, cancer, diabetes, obesity, and chronic kidney disease.
  • 739
  • 27 Jul 2021
Topic Review
Non-Alcoholic Fatty Liver Disease and Cognition
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, affecting approximately 25% of the general population. NAFLD occurs in the absence of excessive alcohol consumption and is closely associated with metabolic syndrome (MetS) and its components.
  • 739
  • 24 Jun 2022
Topic Review
Snack Bars Enriched with Tilapia
Snack bars (SBs), well-known as cereal bars, have been commonly consumed worldwide because they provide instant energy and are convenient to carry around. SBs moderate direct hunger and influence people’s nutritional status, which is commercially and nutritionally interesting. Most consumers care for their diet and health. Thus, eating SBs can be a source of intake of beneficial nutrients, such as fiber, protein, minerals, and vitamins. SBs are common oat (Avena sativa)-based products, a cereal technological feature that also supplies health benefits and cholesterol-lowering properties associated with β-glucan, a soluble-type dietary fiber. However, oat-based SBs are typically deficient and limited in their amino acid profile, especially in threonine and methionine. This condition can be improved by adding complementary protein sources such as legume or animal proteins (good sources of threonine and methionine), increasing the protein and fiber content and improving the bioactive content in the product.
  • 731
  • 23 Aug 2021
Topic Review
Alcohol, Drinking Pattern, and Chronic Disease
Alcohol is an addictive substance consumed worldwide, especially in European countries. Recommendations on alcohol consumption are controversial. On one hand, many nonrandomized studies defend that moderate consumption has a beneficial cardiovascular effect or a lower risk of all-cause mortality. On the other hand, alcohol is associated with an increased risk of cancer, neurological diseases, or injuries, among others.
  • 730
  • 17 May 2022
Topic Review
Dietary Management and Crohn’s Disease
It has been widely endorsed that a multifactorial etiology, including interaction between genetic and environmental factors, can contribute to Crohn’s Disease (CD) pathogenesis. More specifically, diet has proven to be able to shape gut microbiota composition and thus is suspected to play a significant role in inflammatory bowel disease (IBD) pathogenesis. Moreover, poor nutritional status and growth retardation, arising from several factors such as reduced dietary intake or nutrient leakage from the gastrointestinal tract, represent the hallmarks of pediatric CD. For these reasons, multiple research lines have recently focused on the utilization of dietary therapies for the management of CD, aiming to target concurrently mucosal inflammation, intestinal dysbiosis and optimization of nutritional status. The forerunner of such interventions is represented by exclusive enteral nutrition (EEN), a robustly supported nutritional therapy; however, it is burdened by monotony and low tolerance in the long term. Novel dietary interventions, such as Crohn’s Disease Exclusion Diet or Crohn’s Disease treatment with eating, have shown their efficacy in the induction of remission in pediatric patients with CD.
  • 726
  • 17 May 2021
Topic Review
Osteoporosis after Sleeve Gastrectomy and Roux-En-Y-gastric Bypass
Obesity has become a worldwide epidemic accompanied by adverse health effects. The limited efficiency of traditional weight reduction regimens has led to a substantial increase in the use of bariatric surgery. Sleeve gastrectomy (SG) and Roux-en-Y-gastric bypass (RYGB) are the most used procedures. Preoperatively, the dietary habits of obese individuals might lead to deficiencies in vitamin D and other nutrients affecting bone mineral metabolism. Bariatric surgery with SG or RYGB can aggravate these deficiencies. The various surgical procedures appear to affect nutrient absorption differently. Being purely restrictive, SG may particularly affect the absorption of vitamin B12 and also vitamin D. In contrast, RYGB has a more profound impact on the absorption of fat-soluble vitamins and other nutrients, although both surgical methods induce only a mild protein deficiency. Despite adequate supplementation of calcium and vitamin D, osteoporosis may still occur after the surgery. This might be due to deficiencies in other micronutrients, e.g., vitamin K and zinc. Regular follow-ups with individual assessments and nutritional advice are indispensable to prevent osteoporosis and other adverse postoperative issues.
  • 724
  • 21 Mar 2023
Topic Review
Probiotics in NAFLD
Nonalcoholic fatty liver disease (NAFLD) encompasses a broad spectrum of pathological hepatic conditions ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), which may predispose to liver cirrhosis and hepatocellular carcinoma (HCC). The pathogenesis of NAFLD is closely related to insulin resistance (IR), adiposity and physical inactivity as well as genetic and epigenetic factors corroborate to the development and progression of hepatic steatosis and liver injury. Emerging evidence has outlined the implication of gut microbiota and gut-derived endotoxins as actively contributors to NAFLD pathophysiology probably due to the tight anatomo-functional crosstalk between the gut and the liver. Obesity, nutrition and environmental factors might alter intestinal permeability producing a favorable micro-environment for bacterial overgrowth, mucosal inflammation and translocation of both invasive pathogens and harmful byproducts, which, in turn, influence hepatic fat composition and exacerbated pro-inflammatory and fibrotic processes.
  • 721
  • 27 Jul 2021
Topic Review
Preoperative Fasting
This review and meta-analysis provides rationale for the use of oral carbohydrate loading as preoperative fasting leads to metabolic stress and causes insulin resistance in patients undergoing cardiac surgery.
  • 720
  • 10 Feb 2021
Topic Review
Caenorhabditis elegans for Screening Probiotics with Antiobesity Properties
Due to the role of gut microbiota in the regulation of lipid, glucose, and insulin homeostasis, probiotics with beneficial properties have emerged as an alternative therapeutic tool to ameliorate metabolic diseases-related disturbances, including fat excess or inflammation. Different strains of bacteria, mainly lactic acid bacteria (LAB) and species from the genus Bifidobacterium, have emerged as potential probiotics due to their anti-obesogenic and/or anti-diabetic properties. However, in vivo studies are needed to demonstrate the mechanisms involved in these probiotic features. In this context, Caenorhabditis elegans has emerged as a very powerful simple in vivo model to study the physiological and molecular effects of probiotics with potential applications regarding the different pathologies of metabolic syndrome.
  • 717
  • 18 Feb 2024
Topic Review
Role of Klotho in Hyperglycemia
Hyperglycemic conditions (HG), at early stages of diabetic nephropathy (DN), cause a decrease in podocyte numbers and an aberration of their function as key cells for glomerular plasma filtration. Klotho protein was shown to overcome some negative effects of hyperglycemia. Klotho is also a coreceptor for fibroblast growth factor receptors (FGFRs), the signaling of which, together with a proper rate of glycolysis in podocytes, is needed for a proper function of the glomerular filtration barrier. 
  • 716
  • 10 Aug 2021
Topic Review
Diet in Autosomal Polycystic Kidney Disease
Autosomal polycystic kidney disease (ADPKD) is the most common inherited kidney disease and is characterized by a gradual and slow formation and growth of kidney cysts leading to end-stage kidney disease. Dietary interventions are a fundamental part of chronic kidney disease (CKD) treatment, demonstrated by their impact on slowing the progression of CKD and reducing the accumulation of metabolic products, helping in lowering symptoms of uremia and metabolic acidosis and lowering phosphate levels. Among the dietary regimens, plant-based diets and dietary approaches to stop hypertension (DASH) may be beneficial in slowing CKD progression with their low sodium, saturated fat, phosphate apport, and high fiber intake. In addition, plant-based regimens are alkaline-forming, helping in the reduction of acidosis condition in advanced chronic kidney disease. Similarly, the Mediterranean diet is advantageous in slowing kidney damage progression and cardiovascular disease thanks to the reduction in oxidative stress.
  • 715
  • 15 Jun 2023
Topic Review
Dietary Fibre and Colorectal Adenoma
Colorectal cancer is the third most common cancer among men (after lung and prostate cancer) and the second among women (after breast cancer) worldwide, with approximately 2 new million cases (among both men and women) in 2020. Colorectal cancer is one of the few cancers for which a population screening program is in place practically all over the world. Fibre might play a protective role through several mechanisms, including physical mechanisms, anti-inflammatory properties and prebiotic effects. Results from two extensive and recent meta-analyses confirm the protective role of fibre on colon and rectal cancer risk
  • 710
  • 27 Apr 2021
Topic Review
Nutrition and Health-Related Problems in Super-Aging Societies
Many countries are facing the advent of super-aging societies, where sarcopenia and frailty will become pertinent problems. The prevalence of comorbidities is a major problem in countries with aged populations as elderly people suffer from various diseases, such as diabetes, heart failure, chronic kidney disease and dementia. All of these diseases are associated with sarcopenia and frailty, and they frequently cause falls, fractures, and a decline in activities of daily living. Fractures in the elderly people are associated with bone fragility, which is influenced by diabetes and chronic kidney disease. Nutritional support for chronic disease patients and sarcopenic individuals with adequate energy and protein intake, vitamin D supplementation, blood glucose level management for individuals with diabetes, obesity prevention, nutritional education for healthy individuals, and the enlightenment of society could be crucial to solve the health-related problems in super-aging societies.
  • 707
  • 14 Jul 2023
  • Page
  • of
  • 40
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of COVID-19
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Academic Video Service
Feedback