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Topic Review
The Danish Pharmacy Practice Network
The Danish Network for Pharmacy Practice Research and Development (NUAP) is a network of Danish pharmacy owners and employees and Danish pharmacy practice researchers. The overall aim of the network is to strengthen pharmacy practice and pharmacy practice research in Denmark by providing a forum where researchers and representatives of community pharmacies meet to share knowledge and support evidence-based community pharmacy practice.
  • 864
  • 02 Jul 2021
Topic Review
Antimicrobial Use in COVID-19 Patients
There is an urgent need for further research and guidance in this field, from producing evidence-based guidelines, reassessing biomarkers for antimicrobial stewardship in COVID-19 patients, understanding drivers, benefits, and disbenefits of antibiotic use, and assessing the wider impact of the pandemic on antimicrobial use (AMU) and AMR. In this scoping review, we aim to: add to the research evidence on prevalence and patterns of antimicrobial use in the treatment of COVID-19 patients; identify the most commonly used antibiotics and clinical scenarios associated with AMU; and to explore any impact of AMU on patient treatment outcomes.
  • 863
  • 30 Jun 2021
Topic Review
Effectiveness of COVID-19 Vaccines against Delta (B.1.617.2) Variant
The high transmissibility, mortality, and morbidity rate of the SARS-CoV-2 Delta (B.1.617.2) variant have raised concerns regarding vaccine effectiveness (VE). The short-term effectiveness of the Pfizer-BioNTech, Moderna, AstraZeneca, Bharat Biotech, and CoronaVac vaccines for the prevention of infection and the reduction in the severity of illness and hospitalizations associated with the Delta variant are supported. 
  • 863
  • 06 Jan 2022
Topic Review
Ireland's Experience of Covid-19 and Eating Disorders
Irish society went into one of the most stringent lockdowns in March 2020 due to the COVID-19 pandemic, and barring a few weeks, remains highly restricted at time of writing. This has produced a wide range of challenges for those affected by eating disorders, as well as treatment services and Bodywhys, The Eating Disorders Association of Ireland. Current research indicates that COVID-19 has impacted across three key areas—the experience of those with an eating disorder, the experience of service provision, and the impact on the family situation.
  • 863
  • 29 Mar 2022
Topic Review
Dietary Intake Influences Vitamin Needs during Pregnancy
Numerous approaches demonstrate how nutritional intake can be sufficient to ensure the necessary supply of vitamins. However, it is evident that not all vitamins are contained in all foods, so it is necessary either to combine different food groups or to use a vitamin supplement to be well-fed. During pregnancy, deficiencies are often exacerbated due to increased energy and nutritional demands, causing adverse outcomes in mother and child. Micronutrient supplementation could lead to optimal pregnancy outcomes being essential for proper metabolic activities that are involved in tissue growth and functioning in the developing fetus. In order to establish adequate vitamin supplementation, various conditions should be considered, such as metabolism, nutrition and genetic elements.
  • 863
  • 14 Jun 2022
Topic Review
Dietary Assessment Tools and Metabolic Syndrome
Metabolic syndrome (MS) is associated with a range of chronic diseases, for which lifestyle interventions are considered the cornerstone of treatment. Dietary interventions have primarily focused on weight reduction, usually via energy restricted diets. While this strategy can improve insulin sensitivity and other health markers, weight loss alone is not always effective in addressing all risk factors associated with MS.
  • 862
  • 13 Apr 2022
Topic Review
Impact of Premenstrual Syndrome on Quality of Life
Most women who menstruate experience various physical, psychological, and behavioral changes during the period between ovulation and menstruation. 
  • 862
  • 29 Jan 2024
Topic Review
QoL of Cancer Patients Receiving Enteral Nutrition
Most studies supported the positive influence of enteral nutrition on the quality of life, either assessed based on the psychological measures of the quality of life or by considering the other potential determinants (e.g., malnutrition, complications, etc.). Taking this into account, enteral nutrition should be applied whenever possible, both to prevent and treat malnutrition in cancer patients. However, considering the limited number of studies conducted so far, further research conducted in homogenic populations of patients is necessary.
  • 860
  • 20 Jan 2022
Topic Review
Autonomous Wheelchair Navigation
As automated driving system (ADS) technology is adopted in wheelchairs, clarity on the vehicle’s imminent path becomes essential for both users and pedestrians. For users, understanding the imminent path helps mitigate anxiety and facilitates real-time adjustments. For pedestrians, this insight aids in predicting their next move when near the wheelchair.
  • 860
  • 19 Jan 2024
Topic Review
Spaceflight Associated Neuro-Ocular Syndrome (SANS)
Spaceflight associated neuro-ocular syndrome (SANS) is a unique neuro-ophthalmic phenomenon that has been observed in astronauts who have undergone long-duration spaceflight. The syndrome is characterized by distinct imaging and clinical findings including optic disc edema, hyperopic refractive shift, posterior globe flattening, and choroidal folds. SANS serves a large barrier to planetary spaceflight such as a mission to Mars and has been noted by the National Aeronautics and Space Administration (NASA) as a high risk based on its likelihood to occur and its severity to human health and mission performance. While it is a large barrier to future spaceflight, the underlying etiology of SANS is not well understood. However, several well-developed hypotheses have been proposed and countermeasures have been developed.
  • 859
  • 10 Aug 2023
Topic Review
Pregnancy Calcium-Deficiency, Offspring Insulin Resistance
Adverse nutritional conditions during pregnancy may permanently alter the structure or function of specific organs in the offspring, leading to various chronic diseases in adulthood. Maternal undernutrition, and the consequent low birth weight of offspring, predisposes the offspring to various diseases, including adult-onset insulin resistance syndrome. Calcium (Ca) plays an important role in the pathogenesis of insulin resistance syndrome. Cortisol, the most important glucocorticoid, is considered to lead to insulin resistance and metabolic syndrome. 11β-hydroxysteroid dehydrogenase-1 is a key enzyme that catalyzes the intracellular conversion of cortisone to physiologically active cortisol. 
  • 857
  • 02 Aug 2021
Topic Review
Urine HPV Testing
Urine HPV detection has the potential to become a most promising tool that could expand the possibilities in changing genital and cervical cancer prevention strategies as well as in the surveillance and management of genital precancer.
  • 856
  • 21 Apr 2021
Topic Review
Simulation-Based Education in Trauma Management
Trauma injuries are an important healthcare problem and one of the main leading causes of death worldwide. Researchers analyzed current practices in teaching trauma management using simulations, with the aim of summarizing them, identifying gaps and providing a critical overview on what has already been achieved.
  • 856
  • 25 Nov 2022
Topic Review
Asthma and Chronic Obstructive Pulmonary Diseases
Asthma and chronic obstructive pulmonary disease (COPD) are prevalent chronic pulmonary diseases requiring ongoing self-management. According to the World Health Organization, approximately 339 million people worldwide have asthma, and over 65 million suffer from moderate-to-severe COPD, making it the third leading cause of death worldwide. Asthma typically starts early in life and is related to an allergy, whereas COPD is typically caused by air pollutants such as cigarette smoke or biomass fuel.
  • 853
  • 19 Nov 2021
Topic Review
Undergraduate Students' Online Health Information-Seeking Behavior during COVID-19
As the COVID-19 pandemic has swept across the world, the amount of health-related information available has skyrocketed. Individuals can easily access health information through the internet, which may influence their thoughts or behavior, causing potential technological risks that may affect their lives. 
  • 853
  • 29 Dec 2021
Topic Review
Preventing Complications of Type-2 Diabetes
Diabetes is a major public health concern that is approaching epidemic proportions globally [1]. About 422 million people worldwide have diabetes, and 1.6 million deaths are directly attributed to diabetes each year. The most common is the type 2 diabetes. In the past three decades, the prevalence of type 2 diabetes has risen dramatically in countries of all income levels [2].
  • 852
  • 20 Aug 2021
Topic Review
Impact of ERK5 on the Hallmarks of Cancer
Extracellular signal-regulated kinase 5 (ERK5) belongs to the mitogen-activated protein kinase (MAPK) family that consists of highly conserved enzymes expressed in all eukaryotic cells and elicits several biological responses, including cell survival, proliferation, migration, and differentiation.
  • 852
  • 14 Jan 2022
Topic Review
Metabolic Syndrome, Cognitive Impairment and Diet
Early MetS detection may be helpful to prevent or delay cognitive decline. Moreover, this study highlights the importance of healthy nutritional habits to reverse such conditions and the urgency of early lifestyle interventions. 
  • 851
  • 18 Jan 2022
Topic Review
Gastrointestinal Symptoms in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that presents with restrictive, repetitive patterns of behavior, interests, and activities, and/or deficits in communication and social interactions, which typically manifest within the first three years of life. Individuals with ASD frequently have comorbidities and they are at greater risk of experiencing co-occurring gastrointestinal (GI) symptoms, including constipation, diarrhea, and abdominal pain.
  • 851
  • 11 Apr 2022
Topic Review
COVID-19 Vaccination in Developing Nations
Vaccines offer a hope toward ending the global pandemic caused by SARS-CoV2. Mass vaccination of the global population offers hope to curb the spread. Developing nations, however, face monumental challenges in procurement, allocation, distribution and uptake of vaccines. Inequities in vaccine supply are already evident with resource-rich nations having secured a large chunk of the available vaccine doses for 2021. Once supplies are made available, vaccines will have to be distributed and administered to entire populations—with considerations for individual risk level, remote geography, cultural and socio-economic factors. This would require logistical and trained personnel support that can be hard to come by for resource-poor nations. Several vaccines also require ultra-cold temperatures for storage and transport and therefore the need for specialized equipment and reliable power supply which may also not be readily available. Lastly, attention will need to be paid to ensuring adequate uptake of vaccines since vaccine hesitancy has already been reported for COVID vaccines. However, existing strengths of local and regional communities can be leveraged to provide innovative solutions and mitigate some of the challenges. Regional and international cooperation can also play a big role in ensuring equity in vaccine access and vaccination.
  • 850
  • 21 May 2021
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