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All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
ITGA2B Gene
Integrin subunit alpha 2b
  • 686
  • 23 Dec 2020
Topic Review
CLCNKB Gene
chloride voltage-gated channel Kb
  • 686
  • 24 Dec 2020
Topic Review
LIMK1 Gene
LIM domain kinase 1
  • 685
  • 23 Dec 2020
Topic Review
ATP6V0A2 Gene
ATPase H+ transporting V0 subunit a2
  • 685
  • 24 Dec 2020
Topic Review
Combined Oxidative Phosphorylation Deficiency 1
Combined oxidative phosphorylation deficiency 1 is a severe condition that primarily impairs neurological and liver function.
  • 685
  • 24 Dec 2020
Topic Review
CEP57 Gene
centrosomal protein 57
  • 685
  • 24 Dec 2020
Topic Review
Chilling Requirement Validation
The introduction of herbaceous peony (Paeonia lactiflora Pall.) in low-latitude areas is of great significance to expand the landscape application of this world-famous ornamental. With the hazards of climate warming, warm winters occurs frequently, which makes many excellent northern herbaceous peony cultivars unable to meet their chilling requirements (CR) and leads to their poor growth and flowering in southern China. Exploring the endodormancy release mechanism of underground buds is crucial for improving low-CR cultivar screening and breeding. 
  • 685
  • 31 Aug 2021
Topic Review
Genetic Control of Avian Migration
Twice-a-year, large-scale movement of billions of birds across latitudinal gradients is one of the most fascinating behavioral phenomena seen among animals. These seasonal voyages in autumn southwards and in spring northwards occur within a discrete time window and, as part of an overall annual itinerary, involve close interaction of the endogenous rhythm at several levels with prevailing photoperiod and temperature. The overall success of seasonal migrations thus depends on their close coupling with the other annual sub-cycles, namely those of the breeding, post-breeding recovery, molt and non-migratory periods. There are striking alterations in the daily behavior and physiology with the onset and end of the migratory period, as shown by the phase inversions in behavioral (a diurnal passerine bird becomes nocturnal and flies at night) and neural activities. Interestingly, there are also differences in the behavior, physiology and regulatory strategies between autumn and spring (vernal) migrations. Concurrent molecular changes occur in regulatory (brain) and metabolic (liver, flight muscle) tissues, as shown in the expression of genes particularly associated with 24 h timekeeping, fat accumulation and the overall metabolism.
  • 685
  • 16 Jun 2023
Topic Review
Other Histone Modifications Dynamics in Early Embryonic Development
Mammalian fertilization initiates the reprogramming of oocytes and sperm, forming a totipotent zygote. During this intricate process, the zygotic genome undergoes a maternal-to-zygotic transition (MZT) and subsequent zygotic genome activation (ZGA), marking the initiation of transcriptional control and gene expression post-fertilization. Histone modifications are pivotal in shaping cellular identity and gene expression in many mammals. 
  • 685
  • 30 Jan 2024
Topic Review
ANKH Gene
ANKH inorganic pyrophosphate transport regulator
  • 684
  • 24 Dec 2020
Topic Review
MTOR Gene
mechanistic target of rapamycin kinase
  • 683
  • 23 Dec 2020
Topic Review
STK11 Gene
Serine/threonine kinase 11: The STK11 gene (also called LKB1) provides instructions for making an enzyme called serine/threonine kinase 11.
  • 683
  • 24 Dec 2020
Topic Review
Otospondylomegaepiphyseal Dysplasia
Otospondylomegaepiphyseal dysplasia (OSMED) is a condition characterized by skeletal abnormalities, distinctive facial features, and severe hearing loss.
  • 683
  • 24 Dec 2020
Topic Review
CIITA Gene
class II major histocompatibility complex transactivator
  • 683
  • 24 Dec 2020
Topic Review
COL11A1 Gene
collagen type XI alpha 1 chain
  • 683
  • 24 Dec 2020
Topic Review
Multiple Epiphyseal Dysplasia
Multiple epiphyseal dysplasia is a disorder of cartilage and bone development primarily affecting the ends of the long bones in the arms and legs (epiphyses). There are two types of multiple epiphyseal dysplasia, which can be distinguished by their pattern of inheritance. Both the dominant and recessive types have relatively mild signs and symptoms, including joint pain that most commonly affects the hips and knees, early-onset arthritis, and a waddling walk. Although some people with multiple epiphyseal dysplasia have mild short stature as adults, most are of normal height. The majority of individuals are diagnosed during childhood; however, some mild cases may not be diagnosed until adulthood.
  • 682
  • 23 Dec 2020
Topic Review
ISCU Gene
Iron-sulfur cluster assembly enzyme
  • 681
  • 23 Dec 2020
Topic Review
KANK2 Gene
KN motif and ankyrin repeat domains 2
  • 681
  • 23 Dec 2020
Topic Review
SLC22A12 Gene
solute carrier family 22 member 12
  • 681
  • 24 Dec 2020
Topic Review
Pseudogene Transcripts in Head/Neck Cancer
Once considered nonfunctional, pseudogene transcripts are now known to provide valuable information for cancer susceptibility, including head and neck cancer (HNC), a serious health problem worldwide, with about 50% unimproved overall survival over the last decades. The present review focuses on the role of pseudogene transcripts involved in HNC risk and prognosis. Our study can guide new research to HNC understanding and development of new target therapies.
  • 681
  • 29 Mar 2022
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