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Topic Review
Bladder Exstrophy Epispadias Complex
The bladder exstrophy–epispadias complex (BEEC) is an abdominal midline malformation comprising a spectrum of congenital genitourinary abnormalities of the abdominal wall, pelvis, urinary tract, genitalia, anus, and spine. The vast majority of BEEC cases are classified as non-syndromic and the etiology of this malformation is still unknown.
  • 720
  • 05 Aug 2021
Topic Review
Hereditary Diffuse Gastric Cancer
Hereditary diffuse gastric cancer (HDGC) is an inherited disorder that greatly increases the chance of developing a form of stomach(gastric) cancer.
  • 719
  • 23 Dec 2020
Topic Review
Valuing the Wild
Warming and drought are reducing global crop production with a potential to substantially worsen global malnutrition. As with the green revolution in the last century, plant genetics may offer concrete opportunities to increase yield and crop adaptability. However, the rate at which the threat is happening requires powering new strategies in order to meet the global food demand.
  • 719
  • 09 Oct 2021
Topic Review
JUP Gene
Junction plakoglobin
  • 718
  • 23 Dec 2020
Topic Review
SUCLG1 Gene
Succinate-CoA ligase alpha subunit: The SUCLG1 gene provides instructions for making one part, the alpha subunit, of an enzyme called succinate-CoA ligase.
  • 718
  • 24 Dec 2020
Topic Review
Rothmund-Thomson Syndrome
Rothmund-Thomson syndrome is a rare condition that affects many parts of the body, especially the skin.
  • 718
  • 24 Dec 2020
Topic Review
SOX10 Gene
SRY-box 10
  • 718
  • 24 Dec 2020
Topic Review
FKRP Gene
Fukutin related protein: The FKRP gene provides instructions for making a protein called fukutin-related protein (FKRP). 
  • 718
  • 25 Dec 2020
Topic Review
Raynaud Phenomenon
Raynaud phenomenon is a condition in which the body's normal response to cold or emotional stress is exaggerated, resulting in abnormal spasms (vasospasms) in small blood vessels called arterioles.
  • 717
  • 24 Dec 2020
Topic Review
CRISPR/Cas9-Mediated Gene Editing System
The natural CRISPR-Cas9 system are composed of Cas9, crRNA, and tracrRNA. The artificial CRISPR/Cas9 system usually consists of two components: the Cas9 endonuclease and the sgRNA, which form the ribonucleoprotein complex via base pairing to mediate the gene editing. 
  • 717
  • 11 Jan 2024
Topic Review
Genitopatellar Syndrome
Genitopatellar syndrome is a rare condition characterized by genital abnormalities, missing or underdeveloped kneecaps (patellae), intellectual disability, and abnormalities affecting other parts of the body.
  • 716
  • 23 Dec 2020
Topic Review
IL36RN Gene
Interleukin 36 receptor antagonist
  • 716
  • 23 Dec 2020
Topic Review
Other Histone Modifications Dynamics in Early Embryonic Development
Mammalian fertilization initiates the reprogramming of oocytes and sperm, forming a totipotent zygote. During this intricate process, the zygotic genome undergoes a maternal-to-zygotic transition (MZT) and subsequent zygotic genome activation (ZGA), marking the initiation of transcriptional control and gene expression post-fertilization. Histone modifications are pivotal in shaping cellular identity and gene expression in many mammals. 
  • 716
  • 30 Jan 2024
Topic Review
KRT6B Gene
Keratin 6B
  • 716
  • 23 Dec 2020
Topic Review
McLeod Neuroacanthocytosis Syndrome
McLeod neuroacanthocytosis syndrome is primarily a neurological disorder that occurs almost exclusively in boys and men.
  • 715
  • 23 Dec 2020
Topic Review
Melorheostosis
Melorheostosis is a rare bone disease.
  • 715
  • 23 Dec 2020
Topic Review
HNF1B Gene
HNF1 homeobox B
  • 715
  • 23 Dec 2020
Topic Review
LAMB3 Gene
Laminin subunit beta 3
  • 715
  • 23 Dec 2020
Topic Review
RAG1 Gene
recombination activating 1
  • 715
  • 23 Dec 2020
Topic Review
ERCC2 Gene
ERCC excision repair 2, TFIIH core complex helicase subunit
  • 715
  • 24 Dec 2020
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