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Xu, C. Legg-Calvé-Perthes Disease. Encyclopedia. Available online: https://encyclopedia.pub/entry/4504 (accessed on 16 September 2026).
Xu C. Legg-Calvé-Perthes Disease. Encyclopedia. Available at: https://encyclopedia.pub/entry/4504. Accessed September 16, 2026.
Xu, Camila. "Legg-Calvé-Perthes Disease" Encyclopedia, https://encyclopedia.pub/entry/4504 (accessed September 16, 2026).
Xu, C. (2020, December 23). Legg-Calvé-Perthes Disease. In Encyclopedia. https://encyclopedia.pub/entry/4504
Xu, Camila. "Legg-Calvé-Perthes Disease." Encyclopedia. Web. 23 December, 2020.
Legg-Calvé-Perthes Disease
Edit

Legg-Calvé-Perthes disease is a bone disorder that affects the hips. Usually, only one hip is involved, but in about 10 percent of cases, both hips are affected. Legg-Calvé-Perthes disease begins in childhood, typically between ages 4 and 8, and affects boys more frequently than girls.

genetic conditions

References

  1. Chaudhry S, Phillips D, Feldman D. Legg-Calvé-Perthes disease: an overviewwith recent literature. Bull Hosp Jt Dis (2013). 2014;72(1):18-27. Review.
  2. Kannu P, Irving M, Aftimos S, Savarirayan R. Two novel COL2A1 mutationsassociated with a Legg-Calvé-Perthes disease-like presentation. Clin Orthop RelatRes. 2011 Jun;469(6):1785-90. doi: 10.1007/s11999-011-1850-x.
  3. Miyamoto Y, Matsuda T, Kitoh H, Haga N, Ohashi H, Nishimura G, Ikegawa S. Arecurrent mutation in type II collagen gene causes Legg-Calvé-Perthes disease in a Japanese family. Hum Genet. 2007 Jun;121(5):625-9.
  4. Park KW, Rejuso CA, Cho WT, Song HR. Timing of premature physeal closure inLegg-Calve-Perthes Disease. Int Orthop. 2014 Oct;38(10):2137-42. doi:10.1007/s00264-014-2394-y.
  5. Su P, Li R, Liu S, Zhou Y, Wang X, Patil N, Mow CS, Mason JC, Huang D, Wang Y.Age at onset-dependent presentations of premature hip osteoarthritis, avascularnecrosis of the femoral head, or Legg-Calvé-Perthes disease in a single family,consequent upon a p.Gly1170Ser mutation of COL2A1. Arthritis Rheum. 2008Jun;58(6):1701-6. doi: 10.1002/art.23491.
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Entry Collection: MedlinePlus
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Update Date: 23 Dec 2020
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