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Topic Review
SBA-15 synthesis variables
SBA-15 synthetized at different values of time and temperature of the hydrothermal treatment were mixture with tobacco in order to determine the capacity of reduction of toxic and carcirogenic compounds on tobacco smoke. The effect of temperature is not significative but time presents a remarked effect. And a parameter not frequently studied, the aparent density, has been shown the most relevant relation with the results on smoking experimentos. Finally, the effect of reduce the supernatant liquor also has been studied and the results have shown that the material properties remain practically unchanged.
  • 1.4K
  • 01 Nov 2020
Topic Review
Detecting VOC Biomarkers in the Exhaled Breath
In general, volatile organic compounds (VOCs) have a high vapor pressure at room temperature (RT). It has been reported that all humans generate unique VOC profiles in their exhaled breath which can be utilized as biomarkers to diagnose disease conditions. The aforementioned discussions show that the human breath contains a variety of VOCs that serve as biomarkers for various diseases and metabolic problems. Therefore, the real-time monitoring of such VOCs in the exhaled human breath is highly essential to enable non-invasive illness detection. A detailed discussion has been carried out to understand various techniques developed to detect VOCs in very low concentrations of part per million volumes (ppmv), part per billion volumes (ppbv), and part per trillion volumes (pptv).
  • 1.3K
  • 09 Feb 2023
Topic Review
Visual pH Sensors
The pH sensors are gaining widespread attention as non-destructive tools, visible to the human eye, and are capable of real-time and in-situ response.
  • 1.3K
  • 31 May 2021
Topic Review
Fall Risk Assessment Using Wearable Sensors
Fall risk assessment based on wearable sensors can be performed from a long-term perspective, in which sensor data is used to predict subject’s long-term fall risk based on clinical scale scores, or from a short-term approach, where data collected is used to detect pre-fall/unbalanced situations in real-time and consequently identify fall risk events.
  • 1.3K
  • 24 Feb 2022
Topic Review
Bone-Conducted Ultrasound
Bone-conducted ultrasound (BCU) has unique characteristics since ultrasound is audible when it is presented through bone conduction. The most interesting is its perception in patients with profound deafness. Some patients can perceive it and discriminate speech-modulated BCU. Previous reports have suggested that BCU can be used for a hearing aid or tinnitus sound therapy.
  • 1.3K
  • 09 Jun 2021
Topic Review
Chemical Gas Sensors
Nowadays, there is increasing interest in fast, accurate, and highly sensitive smart gas sensors with excellent selectivity boosted by the high demand for environmental safety and healthcare applications. Significant research has been conducted to develop sensors based on novel highly sensitive and selective materials. However, there are still great challenges, specifically in terms of selectivity, which raises the need for combining interdisciplinary fields to build smarter and high-performance gas/chemical sensing devices. This review is divided into two parts: In the first part, we cover the recent developments and limitations of chemresistive gas sensors and in the second part, machine learning is proposed as a potential approach to efficiently tackle these issues through pattern recognition algorithms.
  • 1.3K
  • 27 Apr 2021
Topic Review
Wet Nanotechnology
Wet nanotechnology (also known as wet nanotech) involves working up to large masses from small ones. Wet nanotechnology requires water in which the process occurs. The process also involves chemists and biologists trying to reach larger scales by putting together individual molecules. While Eric Drexler put forth the idea of nano-assemblers working dry, wet nanotech appears to be the likely first area in which something like a nano-assembler may achieve economic results. Pharmaceuticals and bioscience are central features of most nanotech start-ups. Richard A.L. Jones calls nanotechnology that steals bits of natural nanotechnology and puts them in a synthetic structure biokleptic nanotechnology. He calls building with synthetic materials according to nature's design principles biomimetic nanotechnology. Using these guiding principles could lead to trillions of nanotech robots, that resemble bacteria in structural properties, entering a person's blood stream to do medical treatments.
  • 1.3K
  • 29 Sep 2022
Topic Review
Engineering Drug Delivery Systems
Engineering drug delivery systems (DDS) aim to release bioactive cargo to a specific site within the human body safely and efficiently. Hydrogels have been used as delivery matrices in different studies due to their biocompatibility, biodegradability, and versatility in biomedical purposes. Microparticles have also been used as drug delivery systems for similar reasons. The combination of microparticles and hydrogels in a composite system has been the topic of many research works. These composite systems can be injected in loco as DDS. The hydrogel will serve as a barrier to protect the particles and retard the release of any bioactive cargo within the particles. Additionally, these systems allow different release profiles, where different loads can be released sequentially, thus allowing a synergistic treatment. The reported advantages from several studies of these systems can be of great use in biomedicine for the development of more effective DDS.
  • 1.3K
  • 04 Oct 2021
Topic Review
Optical Properties of Mn-Doped CuGa(In)S-ZnS Nanocrystals (NCs)
Mn-doped binary NCs have average fluorescence lifetimes in the range of sub-milliseconds and/or need high energy for excitation, or they contain the toxic elements of Cd and/or Se against biosensing/imaging applications.
  • 1.3K
  • 11 Apr 2022
Topic Review
Digital Twins for Home Remote Motor Rehabilitation
The COVID-19 pandemic created the need for telerehabilitation development, while Industry 4.0 brought the key technology. As motor therapy often requires the physical support of a patient’s motion, combining robot-aided workouts with remote control is a promising solution. This may be realised with the use of the device’s digital twin so as to give it an immersive operation. Such technology may be used for manual remote kinesiotherapy, combined with the safety systems predicting potentially harmful situations. The concept is universally applicable to rehabilitation robots.
  • 1.3K
  • 18 Jan 2023
Topic Review
Neuroprotection and Non-Invasive Brain Stimulation
Non-Invasive Brain Stimulation (NIBS) techniques, such as transcranial Direct Current Stimulation (tDCS) and repetitive Magnetic Transcranial Stimulation (rTMS), are well-known non-pharmacological approaches to improve both motor and non-motor symptoms in patients with neurodegenerative disorders. Their use is of particular interest especially for the treatment of cognitive impairment in Alzheimer’s Disease (AD), as well as axial disturbances in Parkinson’s (PD), where conventional pharmacological therapies show very mild and short-lasting effects. However, their ability to interfere with disease progression over time is not well understood; recent evidence suggests that NIBS may have a neuroprotective effect, thus slowing disease progression and modulating the aggregation state of pathological proteins. 
  • 1.3K
  • 23 Nov 2022
Topic Review
Stimuli-Responsive Hydrogels in Drug Delivery
Stimuli-responsive hydrogels, also known as smart hydrogels, exhibit responsiveness to diverse external stimuli. These gels can undergo reversible or irreversible changes in physical or chemical properties upon exposure to stimuli, enabling a highly controllable drug release pattern. This capability contributes to achieving precise drug administration and enhancing treatment effectiveness and safety.
  • 1.3K
  • 24 Oct 2023
Topic Review
Smartphone-Based Biosensor Devices for Healthcare
Electrochemical biosensors are undoubtedly the most popular among POC devices due to their high sensitivity, simplicity, low cost, and reliability. The development of these electrochemical devices has continued to grow exponentially since Clark designed the first enzymatic glucose biosensor, which was then improved and became the most commercialized healthcare biosensor. Electrochemical biosensors that use smartphones received great attention as they use a friendly semi-automated user interface with minimum extra tailored hardware. They can also be used at home, offering an interesting, cost-effective alternative.
  • 1.3K
  • 11 Mar 2022
Topic Review
Hyperlipidemic Rabbit Models
Hyperlipidemia is a major risk factor for atherosclerotic diseases. Experimental animals play an important role in elucidating the molecular mechanisms of the pathophysiology of hyperlipidemia as well as in drug development. Rabbits are one of the most suitable models to study human hyperlipidemia because many features of the lipoprotein metabolism of rabbits are similar to those of humans. Currently, three types of rabbit models are commonly used for studying hyperlipidemia: (1) diet-induced hyperlipidemic rabbits, (2) spontaneous hyperlipidemic rabbits, and (3) gene-manipulated rabbits (transgenic and knockout rabbits).
  • 1.3K
  • 07 Jan 2021
Topic Review
Endoscopy Lifetime Systems Architecture
Systems engineering captures the desires and needs of the customer to conceptualize a system from the overall goal down to the small details prior to any physical development. While many systems projects tend to be large and complicated (i.e., cloud-based infrastructure, long-term space travel shuttles, missile defense systems), systems engineering can also be applied to smaller, complex systems. The system of interest is the endoscope, a standard biomedical screening device used in laparoscopic surgery, screening of upper and lower gastrointestinal tracts, and inspection of the upper airway.
  • 1.3K
  • 25 Oct 2022
Topic Review
Fe0-based environmental remediation
The technology of using metallic iron (Fe0) for in situ generation of iron oxides for water treatment is a very old one. The Fe0 remediation technology has been re-discovered in the framework of groundwater remediation using permeable reactive barriers (PRBs). Despite its simplicity, the improvement of Fe0 PRBs is fraught with difficulties regarding their operating modes. The literature dealing with Fe0 remediation contains ambiguities regarding its invention and its development. The present paper examines the sequence of contributions prior to the advent of Fe0 PRBs in order to clarify the seemingly complex picture.
  • 1.3K
  • 26 Aug 2020
Topic Review
Advances in Translational Nanotechnology
       The burgeoning field of nanotechnology aims to create and deploy nanoscale structures, devices, and systems with novel, size-dependent properties and functions. The nanotechnology revolution has sparked radically new technologies and strategies across all scientific disciplines, with nanotechnology now applied to virtually every area of research and development in the US and globally. NanoFlorida was founded to create a forum for scientific exchange, promote networking among nanoscientists, encourage collaborative research efforts across institutions, forge strong industry-academia partnerships in nanoscience, and showcase the contributions of students and trainees in nanotechnology fields. The 2019 NanoFlorida International Conference expanded this vision to emphasize national and international participation, with a focus on advances made in translating nanotechnology. This review highlights notable research in the areas of engineering especially in optics, photonics and plasmonics and electronics; biomedical devices, nano-biotechnology, nanotherapeutics including both experimental nanotherapies and nanovaccines; nano-diagnostics and -theranostics; nano-enabled drug discovery platforms; tissue engineering, bioprinting, and environmental nanotechnology, as well as challenges and directions for future research.
  • 1.3K
  • 30 Oct 2020
Topic Review
Polymeric Platforms and Delivery Systems of Probiotics
The selection of optimal material for probiotic encapsulation and the appropriate processing route are key parameters to ensure an efficient delivery strategy, where early degradation by GIT stimuli and harsh conditions are largely avoided. Nevertheless, selecting the materials for superior performance in complex physiological environments such as the GIT is a task made challenging not only by the obstacles to be overcome to reach the target site but also by the need to maintain high biological activities and positive responses to the changing surroundings. The fast-growing notion that encapsulates can be composed of active biomaterials should be driven by matching the material’s properties with expected responses through the GIT. Particularly, polymers exhibit versatile molecular moieties that have been widely exploited to fabricate chemical and physical delivery platforms with properties that can be finely tuned by adjusting interchain interactions. Chemical polymeric scaffolds are formed by covalent bonds between adjacent chains, while the physical ones are maintained together by charged polyvalent surfactants or ion interactions. Moreover, their versatile processability schemes facilitate obtaining different morphologies, functionalities, and the possibility to form composites with nanostructured materials in search of an enhanced response when subjected to a stimulus. Typical polymeric encapsulates comprise microparticles, microspheres, microcapsules, hydrogels, and, more recently, nanocomposite 3D matrices.
  • 1.3K
  • 17 Mar 2022
Topic Review
BAW-Based Separation
Bulk acoustic waves have been applied to microfluidic separations with many benefits, such as flexible placement of transducer, simple, and versatile setups. A BAW-based microfluidic device typically operates with bulk acoustic standing waves in a microchannel between two parallel opposite walls. BAW-based microfluidic separation techniques have been applied in separating various types of particles and biological samples based on their size, density and compressibility.
  • 1.3K
  • 26 Oct 2020
Topic Review
Biological Killing by Cold Plasma
Cold Atmospheric Plasma (CAP) is a near-room-temperature partially ionized gas, composed of reactive oxygen and nitrogen species. CAP also generates physical factors, including ultraviolet irradiation, thermal emission, and an electromagnetic (EM) effect. The multimodal chemical and physical nature of CAP makes it a suitable, controllable, flexible, and even a self-adaptive tool for many medical and biological applications, ranging from microorganism sterilization, dermatitis, wound healing, and cancer therapy. It is promising that CAP could help to mitigate the COVID 19 pandemic by effectively inactivating the SARS-CoV-2 virus on diverse surfaces.  Biological killing is a foundation to understand these applications. Reactive species and their radical effects are the foundation to cause the CAP-based biological destruction in most cases. Basically, plasma medicine has even been regarded as a reactive species-based medicine. Here, we provide a systematic introduction and critical summary of the entire picture of biological killing due to CAP treatment and corresponding mechanisms based on the latest discoveries. This work provides guiding principles for diverse applications of CAP in modern biotechnology and medicine.
  • 1.3K
  • 28 Sep 2021
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