Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Helena Kang -- 173 2026-10-09 07:53:33

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Kang, H. Ion Trap Spectrometry. Encyclopedia. Available online: https://encyclopedia.pub/entry/60710 (accessed on 12 November 2026).
Kang H. Ion Trap Spectrometry. Encyclopedia. Available at: https://encyclopedia.pub/entry/60710. Accessed November 12, 2026.
Kang, Helena. "Ion Trap Spectrometry" Encyclopedia, https://encyclopedia.pub/entry/60710 (accessed November 12, 2026).
Kang, H. (2026, October 09). Ion Trap Spectrometry. In Encyclopedia. https://encyclopedia.pub/entry/60710
Kang, Helena. "Ion Trap Spectrometry." Encyclopedia. Web. 09 October, 2026.

Ion Trap Spectrometry

Edit

Radiofrequency electric fields that confine ions in a three-dimensional or linear quadrupole trap, with subsequent mass-selective ejection or isolation, define ion-trap spectrometry. Ions of a chosen mass-to-charge window are stored, optionally fragmented by resonant excitation or ion–molecule reactions, and then scanned out to a detector, so that the trap is both an ion store and a mass analyzer [1]. Quadrupole ion traps coupled to gas or liquid chromatography therefore provide tandem mass spectra from a single analyzer rather than from a beam-type collision cell [2]. Conceptual boundaries exclude magnetic-sector, time-of-flight, and Fourier-transform ICR analyzers, and they exclude ion-mobility spectrometry that separates ions by collision cross section in a drift gas without RF trapping as the mass-analysis principle. Essential features are an RF trapping potential, a means of mass-selective instability or resonance ejection, and, for tandem work, a controlled activation step inside the trap [3]. The recorded observable remains the mass-to-charge ratio of precursor and product ions.

ion trap quadrupole ion trap tandem mass spectrometry mass-selective ejection
Help expand this entry Share your expertise by adding detailed content and references to improve this entry.
Add content

References

  1. Zhi-Rong Tan; Dong-Sheng Ouyang; Gan Zhou; Lian-Sheng Wang; Zhi Li; Dan Wang; Hong-Hao Zhou; Sensitive bioassay for the simultaneous determination of pseudoephedrine and cetirizine in human plasma by liquid-chromatography–ion trap spectrometry. J. Pharm. Biomed. Anal. 2006, 42, 207-212. [CrossRef]
  2. S Blair; M Song; B Hall; J Brodbelt; Determination of Gamma-hydroxybutyrate in Water and Human Urine by Solid Phase Microextraction-Gas Chromatography/Quadrupole Ion Trap Spectrometry. J. Forensic Sci. 2001, 46, 688-693. [CrossRef]
  3. Pei-Xi Zhu; Dan-Hua Wang; Cui-Rong Sun; Zhi-Quan Shen; Characterization of impurities in the bulk drug lisinopril by liquid chromatography/ion trap spectrometry. J. Zhejiang Univ. B 2008, 9, 385-390. [CrossRef]
More
Upload a video for this entry
Information
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Helena Kang
View Times: 11
Entry Collection: Analytical Chemistry
Revision: 1 time (View History)
Update Date: 21 Oct 2026
Notice
You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
OK
Confirm
Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
Yes
No
${ textCharacter }/${ maxCharacter }
Submit
Cancel
There is no comment~
${ textCharacter }/${ maxCharacter }
Submit
Cancel
${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
Submit
Cancel
Confirm
Are you sure to Delete?
Yes No
Write an Entry